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In Development this week (Vol. 138, Issue 11)

Posted by , on 10 May 2011

Here are the highlights from the current issue of Development: Dronc regulates Numb and neuroblast formation The ability of stem cells to maintain a balance between self-renewal and differentiation is ...
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Zinc Finger Nucleases targeting genes in a frog near you!

Posted by , on 9 May 2011

Loss-of-function studies in Xenopus have been, until recently, limited to transient knockdowns by injection of morpholino antisense oligonucleotides.  In part because of X. laevis’ complex allotetraploid genome, the system lacked ...
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The story behind the screen - flashbacks from the first RNAi screen in a whole vertebrate

Posted by , on 9 May 2011

The story of our recently released Development paper ‘FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools’ (http://dev.biologists.org/content/138/10/1893.full) involves hundreds of dozens ...
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Healing an injured heart

Posted by , on 5 May 2011

Regenerative medicine and stem cell research go hand-in-hand when it comes to dreaming up future strategies for treating disease and injury in humans.  Today’s image is from a recent Development ...
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March of Dimes Prize Announced

Posted by , on 4 May 2011

The March of Dimes Prize in Developmental Biology was jointly awarded this April to David Page, Director of the Whitehead Institute, and Patricia Ann Jacobs, professor of human genetics at ...
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An After Thought to Evolution: Exceptional ways of Controlling Gene “Expression”

Posted by , on 3 May 2011

More and more, the central dogma is becoming well, dogged, for being a dogma at all. As humans, we have 3 billion nucleotides. Only 1% of it makes up our ...
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Science – The Bigger Picture

Posted by , on 1 May 2011

This is a retelling of the student and post-doc workshop from the second day of the BSDB/BSCB joint spring meeting that took place in Canterbury at the University of Kent. ...
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Rethinking X-chromosome Inactivation

Posted by , on 30 April 2011

I’ve been asked to present the back-story behind our recently published manuscript in Development “Transcription precedes loss of Xist coating and depletion of H3K27me3 during X-chromosome reprogramming in the mouse ...
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Stem cell patent case could have far-reaching impact

Posted by , on 28 April 2011

Last month, the advocate-general of the European Court of Justice gave his opinion on a long-running legal debate about a patent filed several years ago in Germany. If the Court follows his ...
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Got the Blues? How Plants Respond to Blue Light

Posted by , on 28 April 2011

Physiologically speaking of course.... As humans we can see a limited assortment of light wavelengths, known as the visible spectrum of light, a.k.a. colours. (Other wavelengths we cannot see include UV ...
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