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Displaying posts in the category: Research

Just because it looks like a duct, doesn’t mean it is the duct

Posted by , on 25 January 2011

The Node’s staff has kindly given me the opportunity to write a background piece, placing into context the results of our studies described in the paper, “Sox9+ ductal cells are ...

RNAi in the Nucleus ~ It’s no longer limited to the cytoplasm

Posted by , on 18 January 2011

Hot off the press from the holidays is an article from PNAS that’s worth a gander if you’re into RNAi. We know RNAi associated with epigenetics is possible in the ...

Arrested Development in Plant miRNA Mutants

Posted by , on 11 January 2011

Animals and Plants have hundreds of miRNAs with diverse roles in gene regulation. In humans, each miRNA family can control up to several hundred genes (or 500 to be exact, ...

modENCODE

Posted by , on 6 January 2011

The modENCODE project (model organism encyclopedia of DNA elements) is a collaborative effort to identify all sequence-based functional elements of Drosophila and C. elegans. The project has now produced almost ...

Intestinal stem cell regeneration

Posted by , on 5 January 2011

Cancer and stem cells are two very loaded biology concepts, and more frequently can be found in the same discussion.  Stem cells within tumors are able to divide and provide ...

In Development this week (Vol. 138, Issue 3)

Posted by , on 4 January 2011

Here are the research highlights from the new issue of Development: Wnt/PCP signalling, microtubules and gastrulation During vertebrate gastrulation, convergence and extension (C&E) movements shape the germ layers to form ...

Celebrating NYE with Bioluminescence

Posted by , on 31 December 2010

Let me take you on a Bioluminescent journey across many kingdoms. If you’re not well acquainted with the term, it’s the ability of living things to chemically produce light. It’s also ...

GFP, YFP and RFP = Christmas Themes!

Posted by , on 22 December 2010

The other beauty of Fluorescent Reporter Gene Systems is its unbearable likeness to holiday colours.

In Development this week (Vol. 138, Issue 2)

Posted by , on 21 December 2010

Boning up on stem cell Igf2-P2 function The insulin-like growth factor (IGF)/insulin signalling pathway regulates cell proliferation, differentiation, aging and life span. During embryonic development, transcription of the mouse and ...

A Farewell to (frog) Arms (apologies to Hemingway)

Posted by , on 15 December 2010

  The backstory to our recent Developmental Biology paper “The secreted integrin ligand nephronectin is necessary for forelimb formation in Xenopus tropicalis”  includes scenes of several members of the Zimmerman ...

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