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Displaying posts in the category: Research

Research Highlight #3: IL-1 regulates haematopoietic stem cell pool size via PU.1

Posted by , on 25 May 2020

Today, we move to mouse adult haematopoiesis, with an elegant work on inflammation and stem cell biology. As always, feedback is more than welcome! Chronic inflammation is one of the ...

Research Highlight #2: Blood stem cells heterogeneity arises from accessible chromatin

Posted by , on 18 May 2020

Hi there! Today’s highlight is focusing on a major question for the haematology community: what is causing blood stem cell heterogeneity? Please do not hesitate to let me know your ...

Cilia, Reissner Fiber and Crooked Spines

Posted by , on 18 May 2020

Perhaps the most exciting aspect of attending any scientific meeting is the privilege of becoming aware of novel research findings in our fields of interest, prior to their appearance in ...

Shaping the embryo towards gastrulation

Posted by , on 13 May 2020

Kyprianou, C., Christodoulou, N., Hamilton, R.S. et al. Basement membrane remodelling regulates mouse embryogenesis. Nature (2020). doi.org/10.1038/s41586-020-2264-2 Morphogenesis is a complicated network of processes that involve cell shape changes, cell movements ...

Research Highlight #1: Inhibition of cell cycle regulators alters the EHT

Posted by , on 12 May 2020

Hello everyone! My name is Alessandro, I am a postdoc in love with science, stem cells and blood! I am also a big fan of the Node, The Company of ...

Birds take flight with help from Sonic hedgehog

Posted by , on 6 May 2020

A Press Release from Development Flight feathers are amazing evolutionary innovations that allowed birds to conquer the sky. A study led by Matthew Towers (University of Sheffield, UK) and Marian ...

Crafting plots for movies

Posted by , on 6 May 2020

In a previous blog I explained how animated plots can be made to illustrate the dynamics of data. Animated plots go nicely together with the movies from which the data ...

Dynamic display of data with animated plots

Posted by , on 27 April 2020

Data from time-lapse experiments is often displayed in a graph or plot, to visualize the dynamics of biological systems (Goedhart, 2020). Ironically, the perception of the dynamics is largely lost ...

Zipping up the neural tube

Posted by , on 21 April 2020

Matteo A. Molè & Andrew J. Copp Molè et al., Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure. Dev. Cell. 52, 321-334.e6 (2020). Zippering is a striking ...

Writing ideas for the Node

Posted by , on 16 April 2020

The Node is a community site for developmental biologists, and is driven by content written by the community – once registered, you are free to post without requiring authorisation or ...

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