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Moving proteins within living embryos using light

Posted by , on 24 February 2016

By Clare Buckley and Rachel Moore One of the things that we find most challenging about working with whole vertebrate organisms is how we can tie ourselves in knots trying ...

Controlling development in a flash: optogenetic modulation of cell contractility during Drosophila morphogenesis

Posted by , on 24 February 2016

Morphogenesis, the shaping of tissues and organs, is driven by a series of events that proceed in a coordinated manner, both spatially and temporally. Such events include changes in cell ...

Identification of a mechanism by which cells interact with their milieu

Posted by , on 23 February 2016

Researchers at IRB Barcelona and CSIC discover a mechanism through which the cells of an organism interact with their extracellular matrix   The cells of an organism interact not only ...

From our sister journals- February 2016

Posted by , on 22 February 2016

Here is some developmental biology related content from other journals published by The Company of Biologists.           Using the developmental biology toolkit to study cancer Aiello ...

Forgotten classics- T. H. Morgan and planarian regeneration

Posted by , on 16 February 2016

  Morgan, T.H. (1898) Experimental studies of the regeneration of Planaria maculata. Archiv für Entwicklungsmechanik der Organismen 7, 364-397 Recommended by Alejandro Sánchez Alvarado (Stowers Institute)   Some classic papers ...

In Development this week (Vol. 143, Issue 4)

Posted by , on 16 February 2016

Here are the highlights from the current issue of Development:   Fishing out a new role for endocannabinoids Endocannabinoids (ECs) are signalling molecules that regulate appetite, mood and pain, and ...

FISHing fish

Posted by , on 15 February 2016

By L. Carine Stapel and Nadine L.Vastenhouw   In developmental biology, the ability to analyze gene expression patterns is essential to address questions about gene regulation and cell fate. In ...

Scientists shed light on how cells with an incorrect number of chromosomes lead to tumour development

Posted by , on 9 February 2016

Aneuploid cells—that is to say those with an abnormal number of chromosomes—are found in most human tumours. A study conducted at IRB Barcelona on the fly Drosophila reveals how surviving ...

Pluripotency in the mouse and beyond…

Posted by , on 4 February 2016

Preimplantation development establishes the founding cell population of the adult mammal in the epiblast. This naïve pluripotent state employs a unique hand of transcription factors to ensure epigenetic resetting and ...

Using the mouse to model human disease: increasing validity and reproducibility

Posted by , on 3 February 2016

This editorial by Monica J. Justice and Paraminder Dhillon was first published in Disease Models & Mechanisms.   ABSTRACT Experiments that use the mouse as a model for disease have recently ...

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