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developmental and stem cell biologists
Posted by Christele Gonneau, on 26 October 2014
Starting with the one fertilized egg that we all once were, embryonic development is made of cell divisions and most importantly of cell decisions. These first life decisions are the ...Posted by Seema Grewal, on 21 October 2014
Here are the highlights from the new issue of Development: Two top tips for angiogenesis The widely accepted model of angiogenic sprouting proposes that a single cell – the ...Posted by Mizushima S, on 18 October 2014
The eggs of domestic birds have been used in the study of developmental biology, leading to the extensive accumulation of knowledge on embryonic development. However, the early events involved in ...Posted by IRBBarcelona, on 8 October 2014
Researchers generate for the first time Drosophila melanogaster with intestinal cancer and reveal key genetic factors behind human colon cancer. The scientists identify a human gene that favours the proliferation ...Posted by Seema Grewal, on 7 October 2014
Here are the highlights from the current issue of Development: Small (molecule) steps to making bone The repair of cartilage and bone following damage remains a clinical challenge. Current ...Posted by Misato Iwashita, on 3 October 2014
To form complex organs, somatic stem cells proliferate and then differentiate during development. In this process, intrinsic factors, i.e. the sequential expression of transcriptional genes, and extrinsic factors, i.e. extracellular ...Posted by pknoepfler, on 2 October 2014
This post was originally published in the Knoepfler Lab Stem Cell Blog. Sometimes in science there are unexpected threads tying seemingly very different things together. Unraveling the ...Posted by Aryeh Warmflash, on 24 September 2014
Waddington, whose writings on the epigenetic landscape continue to influence developmental biology to this day, called the developing embryo “the most intriguing object that nature has to offer”(Waddington, 1966). The ...Posted by Sylvain Bessonnard, on 23 September 2014
During mouse preimplantation development, the zygote divides and forms three distinct lineages: one embryonic called the Epiblast (Epi) and two extraembryonic called trophectoderm (TE) and Primitive Endoderm (PrE). The first ...Posted by Seema Grewal, on 23 September 2014
Here are the highlights from the current issue of Development: Modelling fate decisions in the early mouse embryo In the early embryo, the first fate decision separates the trophectoderm ...