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BBSRC-funded position to study resolution of inflammation

Posted by , on 4 February 2025

Job type:

Location: University of Sheffield

Closing Date: 13 February 2025

A BBSRC-funded Postdoctoral Research Associate position is available (18 months) to study resolution of inflammation using the Drosophila model is available in the Evans lab.

We are looking for an enthusiastic Postdoctoral Research Associate to join us in the School of Medicine and Population Health (https://staff.sheffield.ac.uk/smph) at the University of Sheffield. We have an exciting opportunity for someone with a passion for cell and developmental biology looking to use their skills in genetics and live imaging to make an impact on inflammation. We use fruit flies (Drosophila melanogaster) to understand macrophage cell biology in vivo. Note that Drosophila experience is not a prequisite for this role.

Through our BBSRC-funded project grant, you will address the mechanisms by which macrophages are retained at sites of inflammation: control of immune cell numbers at these locations has important consequences for a broad range of human pathological conditions including chronic wounds, cancer, neurodegenerative diseases and atherosclerosis.

Using fly genetics and live imaging techniques, you will uncover how macrophages are maintained at wounds, while a proteomic approach will be used to identify novel regulators of this process. This will build upon our recent study published in PLoS Biology (Roddie et al., 2019).

Please visit the link below for more information:

https://www.jobs.ac.uk/job/DLQ588/research-associate

Please don’t hesitate to get in touch if you are interested in applying via i.r.evans@sheffield.ac.uk. Drosophila experience is not a prerequisite but would be helpful. Lots of live imaging and genetics here in Sheffield using our amazing fly facilty and imaging set ups.

Sheffield is a lovely place to live and work – it’s close to the beautiful Peak District and is one of the greenest cities in Europe. There is a lot going on in this youthful, dynamic and arty city and it is within easy reach of London, Manchester, Birmingham and Leeds. We share lab space and have great interactions with a range of labs using a variety of models to investigate the cell biology of immune cell behaviour including the Renshaw, Johnston, Elks, Prince, Wilson and King labs.

The closing date for applications is 13th Feb 2025.

 

Salary: £37,999

Closing Date: 13 February 2025

Scientific fields: Cell biology, Development and disease, Haematopoiesis, Homeostasis and aging, Signalling, Regeneration

Model systems: Drosophila

Duration: Fixed term

Minimum qualifications: PhD

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