Postdoctoral position to study the developmental basis of neurodegeneration
Posted by Natalia Rodriguez-Muela, on 4 March 2024
Location: Dresden, Germany
Closing Date: 31 March 2024
Postdoctoral position to study the developmental basis of neurodegeneration
Location: German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany
Closing date: 31 March 2024
Position Overview
This competitive position is available from Spring 2024, for three years, although successful candidates are expected to apply for postdoctoral fellowships. The position is funded through the German Research Foundation (DFG).
The Rodriguez-Muela’s aims to understand the molecular principles that govern the selective neuronal vulnerability characteristic of all neurodegenerative diseases. We specifically focus on the motor neuron diseases SMA and ALS and in Alzheimer’s disease and use as main model system human iPSC-derived 2D and 3D models. For this interdisciplinary project, the recruited postdoc will study SMA and ALS from a development angle and investigate whether these diseases have a neurodevelopmental component that triggers the onset in the postnatal/adult life and which are the underlying mechanistic events.
Education and Experience Requirement
We are searching for an outstanding researcher with a genuine enthusiasm for our research topics and strong background in neuroscience, developmental neurobiology and genetics.
Required:
· PhD degree in biology, biomedicine or related subject
· High quality first-author publication/s in a relevant field
· Human iPSC work, organoid technology, strong cellular and biochemistry techniques (experience in cloning and genome editing are a plus)
· Experience on single cell RNAseq analysis (basic computational knowledge on ATACseq and epigenetics are a plus)
· Strong English communication, organization and interpersonal skills
· Most importantly, lots of curiosity, motivation, creativity and enthusiasm!
The Institute
The Rodríguez-Muela’s lab is a European Research Council (ERC) funded lab and it is based in the German Center for Neurodegenerative Diseases (DZNE-Dresden), a research institute focused on fundamental neuroscience with a translational outlook (www.dzne.de). In addition, Rodríguez-Muela’s lab is also part of the Center for Regenerative Therapies (CRTD) at the TU Dresden, focused on regeneration and stem cell research (www.crt-dresden.de), as well as the Max Planck Institute of Molecular Cell Biology and Genetics (MPI-CBG), pioneering basic research on cell biology, stem cells and organoids (www.mpi-cbg.de). The three of them are multidisciplinary and international research institutes, a couple of minutes walking distance from each other, offering an outstanding research environment and all types of cutting-edge technology platforms.
We offer:
· The opportunity to implement your own ideas and lead an exciting, clinically relevant, research project working in a young, friendly and innovative team of highly motivated scientists.
· Outstanding research environment in biomedicine, neuroscience and stem cell biology that promotes an interdisciplinary and international exchange and offers numerous possibilities for your professional and personal development.
· Access to cutting-edge scientific infrastructure and collaborations with clinical teams.
How to Apply
To apply, please, submit a single PDF with your CV, a statement of research interests and what you would bring to the position, and contact details for at least two references via the link below.
Informal enquiries to discuss the positions are very welcome (natalia.rodriguez-muela@dzne.de, natalia.rodriguez_muela@mailbox.tu-dresden.de).
Closing Date: 31 March 2024
Duration: Fixed term
Minimum qualifications: PhD