Welcome to our monthly trawl for developmental and stem cell biology (and related) preprints.

The preprints this month are hosted on bioRxiv and arXiv – use these links below to get to the section you want:

Developmental biology

• Patterning & signalling
• Morphogenesis & mechanics
• Genes & genomes
• Stem cells, regeneration & disease modelling
• Plant development
• Evo-devo

Cell Biology

Modelling

Tools & Resources

Developmental biology

| Patterning & signalling

Torsion of the heart tube by shortage of progenitor cells : identification of Greb1l as a genetic determinant of criss-cross heart in mice

 Segolene Bernheim,  Adrien Borgel,  Jean Francois Le Garrec,  Emeline Perthame,  Audrey Desgrange,  Wojciech Krezel,  Francesca Raimondi, Damien Bonnet,  Lucile Houyel,  Sigolene Meilhac

A population intrinsic timer controls Hox gene expression and cell dispersion during progenitor addition to the body axis

Lara Busby, Guillermo Serrano Nájera,  Ben Steventon

Lack of apoptosis causes cellular senescence and tumorigenesis in drosophila epithelial cells

Juan Manuel Garcia-Arias, Noelia Pinal, Sara Cristóbal Vargas,  Carlos Estella, Ginés Morata

Opposing roles for TGFβ- and BMP-signaling during nascent alveolar differentiation in the developing human lung

 Tristan Frum,  Peggy P. Hsu,  Renee F.C. Hein,  Ansley S. Conchola,  Charles J. Zhang, Olivia R. Utter, Abhinav Anand, Yi Zhang, Sydney G. Clark,  Ian Glass,  Jonathan Z. Sexton,  Jason R. Spence

OptIC Notch reveals mechanism that regulates receptor interactions with CSL

 Jonathan M. Townson,  Maria J. Gomez-Lamarca,  Carmen Santa Cruz Mateos,  Sarah J. Bray

A short isoform of the UNC-6/Netrin receptor UNC-5 is required for growth cone polarity and robust growth cone protrusion in Caenorhabditis elegans

 Snehal S. Mahadik,  Erik A. Lundquist

Regenerative growth is constrained by brain tumor to ensure proper patterning in Drosophila

 Syeda Nayab Fatima Abidi, Felicity Ting-Yu Hsu,  Rachel K. Smith-Bolton

Apical-driven cell sorting optimised for tissue geometry ensures robust patterning

 Prachiti Moghe,  Roman Belousov,  Takafumi Ichikawa, Chizuru Iwatani,  Tomoyuki Tsukiyama,  Francois Graner,  Anna Erzberger,  Takashi Hiiragi

Dkk2 interacts with Pax9 in palate mesenchyme to pattern and tune osteogenesis

 Jeremie Oliver Pina,  Daniela M Roth,  Resmi Raju,  Emma Wentworth Winchester,  Parna Chattaraj, Fahad K Kidwai,  Fabio R Faucz,  James Iben, Cameron Padilla,  Justin L Cotney,  Rena N D’Souza

Hypoxia delays steroid-induced developmental maturation in Drosophila by suppressing EGF signaling

Michael J Turingan, Tan Li, Jenna Wright, Savraj S Grewal

Wnt/β-catenin signaling controls mouse eyelid growth by mediating epithelial-mesenchymal interactions

 Xuming Zhu, Makoto Senoo,  Sarah E. Millar, Gang Ma

Embryonic organizer specification in the mud snail Ilyanassa obsoleta depends on intercellular signaling

Jessica E. Wandelt, Ayaki Nakamoto,  Morgan Q Goulding,  Lisa Nagy

SRC-1 controls growth cone polarity and protrusion with the UNC-6/Netrin receptor UNC-5 in Caenorhabditis elegans

 Snehal S. Mahadik, Emily K. Burt,  Erik A. Lundquist

Wnt4a is indispensable for genital duct elongation but not for gonadal sex differentiation in the medaka Oryzias latipes

 Akira Kanamori, Ryota Kitani, Atsuko Oota, Koudai Hirano, Taijun Myosho, Tohru Kobayashi, Kouichi Kawamura, Naoyuki Kato, Satoshi Ansai, Masato Kinoshita

Embryonic organizer specification in the mud snail Ilyanassa obsoleta depends on intercellular signaling

Jessica E. Wandelt, Ayaki Nakamoto,  Morgan Q Goulding,  Lisa M. Nagy

| Morphogenesis & mechanics

Contractile ring mechanosensation and its anillin-dependent tuning during early embryogenesis

Christina Rou Hsu, Gaganpreet Sangha, Wayne Fan, Joey Zheng,  Kenji Sugioka

Specification of distinct cell types in a sensory-adhesive organ for metamorphosis in the Ciona larva

Christopher J. Johnson, Florian Razy-Krajka, Fan Zeng, Katarzyna M. Piekarz, Shweta Biliya,  Ute Rothbächer,  Alberto Stolfi

The Role of Lrig1 in the Development of the Colonic Epithelium

 Rachel E. Hopton, Nicholas J. Jahahn,  Anne E. Zemper

Mechanical regulation of substrate adhesion and de-adhesion drives a cell contractile wave during tissue morphogenesis

 Claudio Collinet, Anaïs Bailles,  Thomas Lecuit

Hierarchical Morphogenesis of Swallowtail Butterfly Wing Scale Nanostructures

Kwi Shan Seah,  Vinodkumar Saranathan

Developmental biomechanics and age polyethism in leaf-cutter ants

 Frederik Püffel, Lara Meyer, Natalie Imirzian, Flavio Roces, Richard Johnston,  David Labonte

Inverse blebs operate as hydraulic pumps during mouse blastocyst formation

Markus F. Schliffka, Julien G. Dumortier, Diane Pelzer, Arghyadip Mukherjee,  Jean-Léon Maître

A chemo-mechanical model of endoderm movements driving elongation of the amniote hindgut

 Nandan Nerurkar,  Panagiotis Oikonomou, Helena C Cirne

Quantifying the relationship between cell proliferation and morphology during development of the face

 Rebecca M. Green,  Lucas D. Lo Vercio,  Andreas Dauter,  Elizabeth C. Barretto,  Jay Devine,  Marta Vidal-García,  Marta Marchini,  Samuel Robertson, Xiang Zhao, Anandita Mahika, M. Bilal Shakir, Sienna Guo,  Julia C. Boughner,  Wendy Dean,  Arthur D. Lander,  Ralph S. Marcucio,  Nils D. Forkert,  Benedikt Hallgrímsson

Cardiac competence of the paraxial head mesoderm fades concomitant with a shift towards the head skeletal muscle programme

 Afnan Alzamrooni, Petra Mendes Vieira,  Nicoletta Murciano, Matthew Wolton,  Frank R. Schubert,  Samuel C. Robson,  Susanne Dietrich

EBF1 limits the numbers of cochlear hair and supporting cells and forms the scala tympani and spiral limbus during inner ear development

Hiroki Kagoshima,  Hiroe Ohnishi, Ryosuke Yamamoto, Akiyoshi Yasumoto, Koichi Omori, Rudolf Grosschedl,  Norio Yamamoto

Mitochondrial citrate carrier SLC25A1 is a dosage-dependent regulator of metabolic reprogramming and morphogenesis in the developing heart

Chiemela Ohanele, Jessica N. Peoples, Anja Karlstaedt, Joshua T. Geiger, Ashley D. Gayle, Nasab Ghazal, Fateemaa Sohani, Milton E. Brown, Michael E. Davis, George A. Porter Jr.,  Victor Faundez,  Jennifer Q. Kwong

Endodermal BRD4 mediates epithelial-mesenchymal crosstalk during lung development

Derek C. Liberti, Hongbo Wen, Kwaku K. Quansah, Prashant Chandrasekaran, Josh Pankin,  Nigel S. Michki, Annabelle Jin, MinQi Lu, Maureen Peers De Nieuwburgh, Lisa R. Young, Rajan Jain,  David B. Frank

DNA-guided transcription factor cooperativity shapes face and limb mesenchyme

 Seungsoo Kim,  Ekaterina Morgunova,  Sahin Naqvi, Maram Bader,  Mervenaz Koska,  Alexander Popov,  Christy Luong,  Angela Pogson,  Peter Claes,  Jussi Taipale,  Joanna Wysocka

A role for DNA methylation in bumblebee morphogenesis hints at female-specific developmental erasure

 B. J. Hunt,  M. Pegoraro,  H. Marshall,  E. B. Mallon

Actomyosin remodeling regulates biomineral formation, growth and morphology during eukaryote skeletogenesis

Eman Hijaze, Tsvia Gildor, Ronald Seidel, Majed Layous,  Mark Winter, Luca Bertinetti, Yael Politi,  Smadar Ben-Tabou de-Leon

Inhibitory G proteins play multiple roles to polarize sensory hair cell morphogenesis

 Amandine Jarysta,  Abigail L.D. Tadenev, Matthew Day, Barry Krawchuk, Benjamin E. Low, Michael V. Wiles,  Basile Tarchini

A combination of convergent extension and differential adhesion explains the shapes of elongating gastruloids

Martijn A. de Jong, Esmée Adegeest, Noémie M. L. P. Bérenger-Currias, Maria Mircea, Roeland M. H. Merks,  Stefan Semrau

Endodermal BRD4 mediates epithelial-mesenchymal crosstalk during lung development

Derek C. Liberti, Hongbo Wen, Kwaku K. Quansah, Prashant Chandrasekaran, Josh Pankin,  Nigel S. Michki, Annabelle Jin, MinQi Lu, Maureen Peers De Nieuwburgh, Lisa R. Young, Rajan Jain,  David B. Frank

SPLIT HAND/FOOT VARIANTS FAIL TO RESCUE PRDM1A MUTANT CRANIOFACIAL DEFECTS

Brittany T. Truong, Lomeli C. Shull, Ezra Lencer, Kristin B. Artinger

| Genes & genomes

Chromosome-specific maturation of the epigenome in the Drosophila male germline

James Anderson,  Steven Henikoff,  Kami Ahmad

DMRT1 is a Testis Determining Gene in Rabbits and is Also Essential for Female Fertility

 Emilie Dujardin, Marjolaine Andre, Aurelie Dewaele, Beatrice Mandon-Pepin, Francis Poulat, Anne Frambourg, Dominique Thepot, Luc Jouneau, Genevieve Jolivet, Eric Pailhoux, Maelle Pannetier

Transcriptional and epigenomic profiling identifies YAP signaling as a key regulator of intestinal epithelium maturation

Laura Pikkupeura, Raul Bressan, Jordi Guiu, Yun Chen, Martti Maimets, Daniela Mayer, Pawel Schweiger, Stine Hansen, Grzegorz Maciag, Hjalte Larsen, Kadi Lohmussaar, Marianne Pedersen, Joji Teves, Jette Lange,  Vladimir Benes,  Albin Sandelin,  Kim Jensen

Parallels and contrasts between the cnidarian and bilaterian maternal-to-zygotic transition are revealed in Hydractinia embryos

Taylor N Ayers,  Matthew Nicotra,  Miler T Lee

Rapid evolution of piRNA clusters in the Drosophila melanogaster ovary

 Satyam Srivastav,  Cédric Feschotte, Andrew G. Clark

Spatial transcriptomics reveals novel genes during the remodelling of the embryonic human arterial valves

Rachel Queen, Moira Crosier, Lorraine Eley, Janet Kerwin, Jasmin E. Turner, Jianshi Yu, Tamil Dhanaseelan, Lynne Overman, Hannah Soetjoadi, Richard Baldock, Jonathon Coxhead, Veronika Boczonadi,  Alex Laude,  Simon J. Cockell, Maureen A. Kane,  Steven Lisgo,  Deborah J. Henderson

Molecular signatures associated with successful implantation of the human blastocyst

 Jennifer N. Chousal, Srimeenakshi Srinivasan,  Katherine Lee, Cuong To, Kyucheol Cho, Wei Zhang, Ana Lisa Yeo, V. Gabriel Garzo, Mana M. Parast, Louise C. Laurent,  Heidi Cook-Andersen

Using CRISPR/Cas9 to identify genes required for mechanosensory neuron development and function

Christopher J. Johnson, Akhil Kulkarni, William J. Buxton, Tsz Y. Hui, Anusha Kayastha, Alwin A. Khoja, Joviane Leandre, Vanshika V. Mehta, Logan Ostrowski, Erica G. Pareizs, Rebecca L. Scotto, Vanesa Vargas, Raveena M. Vellingiri, Giulia Verzino, Rhea Vohra, Saurabh C. Wakade, Veronica M. Winkeljohn, Victoria M. Winkeljohn,  Travis M. Rotterman,  Alberto Stolfi

Gene regulatory patterning codes in early cell fate specification of the C. elegans embryo

 Alison G. Cole,  Tamar Hashimshony,  Zhuo Du,  Itai Yanai

Complex aneuploidy triggers autophagy and p53-mediated apoptosis and impairs the second lineage segregation in human preimplantation embryos

 Marius Regin, Yingnan Lei,  Edouard Couvreu De Deckersberg, Yves Guns,  Pieter Verdyck,  Greta Verheyen, Hilde Van de Velde,  Karen Sermon,  Claudia Spits

Identification of a core transcriptional program driving the human renal mesenchymal-to-epithelial transition

 John-Poul Ng-Blichfeldt,  Benjamin J. Stewart,  Menna R. Clatworthy, Julie M. Williams,  Katja Röper

Single cell transcriptomics of the human parasite Schistosoma mansoni first intra-molluscan stage reveals tentative tegumental and stem cell regulators

 Carmen L. Diaz Soria,  Teresa Attenborough,  Zhigang Lu, Jennie Graham, Christopher Hall, Sam Thompson, Toby G. R. Andrews,  Kate A. Rawlinson,  Matthew Berriman,  Gabriel Rinaldi

Comparative single-cell analyses identify shared and divergent features of human and mouse kidney development

 Sunghyun Kim, Kari Koppitch, Riana K. Parvez, Jinjin Guo, MaryAnne Achieng, Jack Schnell,  Nils O. Lindstrom,  Andrew P. McMahon

Single cell transcriptomics of human prenatal anterior foregut-derived organs identifies distinct developmental signatures directing commitment and specialization of the thymic epithelial stroma

Abdulvasey Mohammed,  Priscila Ferreira Slepicka,  Benjamin Solomon,  Kelsea M Hubka, Hanh Dan Nguyen, Michael G Chavez,  Christine Y Yeh,  Virginia D Winn,  Casey A Gifford,  Purvesh Khatri,  Andrew Gentles,  Katja Gabrielle Weinacht

Novel metrics reveal new structure and unappreciated heterogeneity in C. elegans development

Gunalan Natesan, Timothy Hamilton,  Eric J. Deeds,  Pavak K. Shah

The Drosophila drop-dead gene is required for eggshell integrity

 Tayler D. Sheahan, Amanpreet Grewal, Laura E. Korthauer,  Edward M. Blumenthal

Phase transition of maternal RNAs during vertebrate oocyte-to-embryo transition

Hyojeong Hwang, Sijie Chen, Meng Ma, Divyanshi, Hao-Chun Fan, Elizabeth Borwick, Elvan Böke, Wenyan Mei, Jing Yang

Two distinct waves of transcriptome and translatome remodelling drive germline stem cell differentiation

 Tamsin J. Samuels,  Jinghua Gui,  Daniel Gebert,  Felipe K. Teixeira

Warming During Embryogenesis Induces a Lasting Transcriptomic Signature in Fishes

 Daniel M. Ripley, Terence Garner, Samantha A. Hook, Ana Veríssimo,  Bianka Grunow,  Timo Moritz, Peter Clayton,  Holly A. Shiels,  Adam Stevens

Genetics of skeletal proportions in two different populations

 Eric Bartell,  Kuang Lin,  Kristin Tsuo,  Wei Gan,  Sailaja Vedantam,  Joanne B Cole,  John M Baronas,  Loic Yengo,  Eirini Marouli,  Tiffany Amariuta, GIANT Consortium,  Nora E Renthal, Christina M Jacobsen,  Rany Salem,  Robin G Walters,  Joel N Hirschhorn

Enhancer status in the primitive endoderm supports unrestricted lineage plasticity in regulative development

 Madeleine Linneberg-Agerholm, Annika Charlotte Sell,  Alba Redo-Riveiro,  Martin Proks, Teresa E. Knudsen,  Marta Perera,  Joshua M. Brickman

Single Cell Transcriptomics Identifies Distinct Choroid Cell Populations Involved in Visually Guided Eye Growth

 Jody A Summers, Kenneth L Jones

Dissection of anterior mesendoderm segregation at single cell level in zebrafish

 Tao Cheng, Xiang Liu,  Yang Dong, Yan-Yi Xing, Cong Liu, Yun-Fei Li, Ying Huang, Jing-Yun Luan,  Hong-Qing Liang,  Peng-Fei Xu

The Crucial Role of CTCF in Mitotic Progression during Early Development of Sea Urchin

Kaichi Watanabe, Megumi Fujita, Kazuko Okamoto, Hajime Yoshioka, Miki Moriwaki, Hideki Tagashira, Akinori Awazu, Takashi Yamamoto, Naoaki Sakamoto

Extensive DNA methylome rearrangement during early lamprey embryogenesis

 Allegra Angeloni,  Skye Fissette, Deniz Kaya,  Jillian M. Hammond,  Hasindu Gamaarachchi,  Ira W. Deveson,  Robert J. Klose, Weiming Li, Xiaotian Zhang,  Ozren Bogdanovic

| Stem cells, regeneration & disease modelling

The E3 Ubiquitin Ligase Nedd4L Acts as a Checkpoint Against Activation in Quiescent Muscle Stem Cells

Darren Blackburn, Korin Sahinyan, Aldo Hernnandez Corchado, Felicia Lazure, Vincent Richard, Laura Raco, Rene Zahedi, Christoph Borchers, Christoph Lepper, Hiroshi Kawabe, Arezu Jahani-asl,  Hamed S Najafabadi, Vahab D Soleimani

Adrenergic signaling stimulates body-wide stem cell activation for limb regeneration

 Duygu Payzin-Dogru, Sarah E. Wilson, Steven J. Blair,  Aaron M. Savage, Emil Kriukov, Victor Cat, Louis V. Cammarata, Burcu Erdogan, Shifa Hossain,  Noah Lopez, Julia Losner, Juan C. Velazquez Matos, Sangwon Min, Kelly Dooling, Bobby Groves, Alan Y. Wong,  Petr Baranov, Hani Singer,  Isaac M. Chiu,  Brian J. Haas,  Jessica L. Whited

CRISPRi Gene Modulation and All-Optical Electrophysiology in Post-Differentiated Human iPSC-Cardiomyocytes

 Julie L. Han,  Yuli W. Heinson, Christianne J. Chua,  Wei Liu,  Emilia Entcheva

Nutrient-driven dedifferentiation of enteroendocrine cells promotes adaptive intestinal growth

Hiroki Nagai, Luis Augusto Eijy Nagai, Sohei Tasaki,  Ryuichiro Nakato, Daiki Umetsu, Erina Kuranaga, Masayuki Miura,  Yu-ichiro Nakajima

Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury

Natalia A. Veniaminova, Yunlong Jia, Adrien M. Hartigan, Thomas J. Huyge, Shih-Ying Tsai, Marina Grachtchouk, Seitaro Nakagawa, Andrzej A. Dlugosz, Scott X. Atwood, Sunny Y. Wong

Hindbrain boundaries as niches of neural progenitor/stem cells regulated by the extracellular matrix proteoglycan chondroitin sulphate

Carmel Hutchings, Yarden Nuriel, Daniel Lazar, Ayelet Kohl,  Elizabeth Muir, Yuval Nevo, Hadar Benyamini,  Dalit Sela-Donenfeld

A primary microcephaly-associated sas-6 mutation perturbs centrosome duplication, dendrite morphogenesis, and ciliogenesis in Caenorhabditis elegans

Mary Bergwell, Amy Smith, Ellie Smith, Carter Dierlam, Ramon Duran, Erin Haastrup, Rebekah Napier-Jameson, Rory Seidel, William Potter, Adam Norris,  Jyoti Iyer

VEGF-C overexpression in kidney progenitor cells is a model of renal lymphangiectasia

 Michael D. Donnan,  Dilip K. Deb, Valentin David,  Susan E. Quaggin

Six3 and Six6 jointly regulate the identities and developmental trajectories of multipotent retinal progenitor cells in the mouse retina

Alexander Ferrena, Xusheng Zhang, Rupendra Shrestha, Deyou Zheng, Wei Liu

Parallel genome-scale CRISPR screens distinguish pluripotency and self-renewal

Bess P. Rosen, Qing V. Li, Hyunwoo Cho, Dingyu Liu, Dapeng Yang, Sarah Graff, Jielin Yan, Renhe Luo, Nipun Verma, Jeyaram R. Damodaran, Michael A. Beer, Simone Sidoli, Danwei Huangfu

Optimizing spinal cord injury in zebrafish larvae: effects of age on the injury response

 Kirsten L Underwood,  Whitney J Walker,  Patrick I Garrett, Shannon Linch,  Thomas P Rynes,  Karen Mruk

Dual-topology of collagen XV and tenascin C acts in concert to guide and shape developing motor axons

 Laurie Nemoz-Billet,  Martial Balland,  Laurent Gilquin,  Benjamin Gillet,  Isabelle Stevant,  Emilie Guillon,  Sandrine Hughes,  Gilles Carpentier,  Elisabeth Vaganay,  Mary-Julieth Gonzalez-Melo,  Manuel Koch,  Yad Ghavi-Helm,  Florence Ruggiero,  Sandrine Bretaud

Telocytes are a critical source of Wnts essential for hair follicle regeneration

Marco Canella, Simcha Nalick, Noa Corem, Amal Gharbi, Ittai Ben-Porath,  Michal Shoshkes Carmel

Cbl and Cbl-b Ubiquitin Ligases are Essential for Intestinal Epithelial Stem Cell Maintenance

Neha Zutshi,  Bhopal C Mohapatra, Pinaki Mondal, Wei An, Benjamin T Goetz, Shou Wang, Scong Li, Matthew D Storck, David Mercer, Adrian R Black, Sarah P Thayer, Jennifer Black, Chi Lin,  Vimla Band,  Hamid Band

MuSK-BMP signaling in adult muscle stem cells maintains quiescence and regulates myofiber size

Laura Ann Madigan, Diego Jaime, Justin R Fallon

New permanent stem cell niche for development and regeneration in a chordate

 Virginia Vanni,  Federico Caicci,  Anna Peronato,  Graziano Martello,  Davide Asnicar,  Fabio Gasparini,  Loriano Ballarin,  Lucia Manni

The emergence of human gastrulation upon in vitro attachment

Riccardo De Santis, Eleni Rice, Gist Croft, Min Yang, Edwin A. Rosado-Olivieri, Ali H. Brivanlou

Investigating the developmental onset of regenerative potential in the annelid Capitella teleta

 Alicia A. Boyd,  Elaine C. Seaver

Epithelial-Mesenchymal Transition: An Organizing Principle of Mammalian Regeneration

Kamila Bedelbaeva, Benjamin Cameron, Jack Latella, Azamat Aslanukov, Dmitri Gourevitch,  Ramana Davuluri,  Ellen Heber-Katz

Cardiopharyngeal Mesoderm specification into cardiac and skeletal muscle lineages in gastruloids

 Laurent Argiro, Céline Chevalier,  Caroline Choquet,  Nitya Nandkishore, Adeline Ghata,  Anaïs Baudot,  Stéphane Zaffran,  Fabienne Lescroart

DNA damage primes hematopoietic stem cells for direct megakaryopoiesis

Corey M. Garyn, Oriol Bover, John W. Murray, Ma Jing, Karen Jeanina Salas Briceno,  Susan R Ross,  Hans-Willem Snoeck

Accessibility and activity of transcriptional regulatory elements during sea urchin embryogenesis and differentiation

 Cesar Arenas-Mena, Serhat Akin

Fgf10 mutant newts can regenerate normal limbs despite severe developmental hindlimb defects

 Miyuki Suzuki, Akinori Okumrura, Yuki Shibata, Tetsuya Endo, Machiko Teramoto, Akane Chihara, Kiyokazu Agata,  Marianne E. Bronner, Ken-ichi T Suzuki

Cbl and Cbl-b Ubiquitin Ligases are Essential for Intestinal Epithelial Stem Cell Maintenance

Neha Zutshi,  Bhopal C. Mohapatra, Pinaki Mondal, Wei An, Benjamin T. Goetz, Shuo Wang, Sicong Li, Matthew D. Storck, David F. Mercer, Adrian R. Black, Sarah P. Thayer, Jennifer D. Black, Chi Lin,  Vimla Band,  Hamid Band

Differentiation and quality control of smooth muscle cells from human pluripotent stem cells via the neural crest lineage

Peter J Holt, Hongorzul Davaapil, Deeti K Shetty, Aishwarya G Jacob, Sanjay Sinha

Arp2/3 Complex Activity Enables Nuclear YAP for Naive Pluripotency of Human Embryonic Stem Cells

 Nathaniel P Meyer,  Tania Singh,  Matthew L Kutys,  Todd Nystul, Diane L Barber

Modeling kidney development, disease, and plasticity with clonal expandable nephron progenitor cells and nephron organoids

Biao Huang, Zipeng Zeng, Hui Li, Zexu Li, Xi Chen, Jinjin Guo, Chennan C. Zhang, Megan E. Schreiber, Ariel C. Vonk, Tianyuan Xiang, Tadrushi Patel, Yidan Li, Riana K. Parvez, Balint Der, Jyun Hao Chen, Zhenqing Liu, Matthew E. Thornton, Brendan H. Grubbs, Yarui Diao, Yali Dou, Ksenia Gnedeva,  Nils O. Lindström, Qilong Ying, Nuria M. Pastor-Soler, Teng Fei, Kenneth R. Hallows, Andrew P. McMahon, Zhongwei Li

A single cell transcriptomic fingerprint of stressed premature, imbalanced differentiation of embryonic stem cells

Ximena Ruden, Aditi Singh, Teya Marben, Wen Tang, Awoniyi Awonuga, Douglas M. Ruden, Elizabeth Puscheck, Hao Feng,  Daniel Rappolee

Fgf10 mutant newts can regenerate normal limbs despite severe developmental hindlimb defects

 Miyuki Suzuki, Akinori Okumura, Yuki Shibata, Tetsuya Endo, Machiko Teramoto, Akane Chihara, Kiyokazu Agata,  Marianne E. Bronner, Ken-ichi T. Suzuki

Stem cells tightly regulate dead cell clearance to maintain tissue fitness

 Katherine S Stewart, Kevin AU Gonzales, Shaopeng Yuan, Matthew T Tierney, Alain R Bonny, Yihao Yang, Nicole R Infarinato, Christopher J Cowley, John M Levorse, Hilda Amalia Pasolli, Sourav Ghosh, Carla V Rothlin, Elaine Fuchs

Native extracellular matrix promotes human neuromuscular organoid morphogenesis and function

 Beatrice Auletta,  Lucia Rossi, Francesca Cecchinato, Gilda Barbato, Agnese Lauroja, Pietro Chiolerio, Giada Cecconi,  Edoardo Maghin,  Maria Easler,  Paolo Raffa,  Silvia Angiolillo, Wei Qin, Sonia Calabrò, Chiara Villa,  Onelia Gagliano,  Cecilia Laterza,  Davide Cacchiarelli,  Matilde Cescon,  Monica Giomo,  Yvan Torrente,  Camilla Luni,  Martina Piccoli,  Nicola Elvassore,  Anna Urciuolo

Ampk activation by glycogen expenditure primes the exit of naïve pluripotency

 Seong-Min Kim, Eun-Ji Kwon, Ji-Young Oh, Han Sun Kim, Sunghyouk Park, Goo Jang, Jeong Tae Do,  Keun-Tae Kim, Hyuk-Jin Cha

| Plant development

Gibberellin and the miRNA156-targeted SlSBPs synergistically regulate tomato floral meristem activity and fruit patterning

Leticia F. Ferigolo,  Mateus H. Vicente,  Joao P. O. Correa,  Carlos H. Barrera-Rojas,  Eder M. Silva,  Geraldo F.F. Silva,  Airton Carvalho Jr,  Lazaro E.P. Peres,  Guilherme B. Ambrosano,  Gabriel R. A. Margarido,  Robert Sablowski,  Fabio T.S. Nogueira

Three-dimensional fruit growth analysis clarifies developmental mechanisms underlying complex shape diversity in persimmon fruit

Akane Kusumi,  Soichiro Nishiyama,  Ryutaro Tao

3D imaging reveals apical stem cell responses to ambient temperature

 Christian Wenzl,  Jan U. Lohmann

An elastic proteinaceous envelope encapsulates the early Arabidopsis embryo

 Yosapol Harnvanichvech,  Cecilia Borassi, Diaa Eldin S. Daghma,  Hanne M. van der Kooij,  Joris Sprakel,  Dolf Weijers

A mitochondrial regulon for developmental ferroptosis in rice blast

Qing Shen, Fan Yang,  Naweed I Naqvi

An integrative multi-omics approach to draft gene regulatory networks at a cell type resolution

 Danila Voronov,  Periklis Paganos,  Marta S. Magri, Claudia Cuomo,  Ignacio Maeso, Jose Luis Gómez-Skarmeta,  Maria Ina Arnone

Growth and tension in explosive fruit

Gabriella Mosca, Ryan Eng, Milad Adibi, Saiko Yoshida, Brendan Lane, Leona Bergheim, Gaby Weber, Richard S. Smith,  Angela Hay

Histone Deacetylase 19 Regulates Shoot Meristemless Expression In The Carpel Margin Meristem Contributing To Ovule Number Determination And Transmitting Tract Differentiation

S Manrique,  A Cavalleri, A Guazzotti, GH Villarino, S Simonini, A Bombarely, T Higashiyama, U Grossniklaus, C Mizzotti, AM Pereira, S Coimbra, S Sankaranarayanan, E Onelli,  S Masiero, RG Franks, L Colombo

An SMR cell-cycle inhibitor inducible by a carotenoid metabolite resets root development and drought tolerance in Arabidopsis

Jeanne Braat, Meryl Jaonina, Pascale David, Maïté Leschevin, Bertrand Légeret, Stefano D’Alessandro, Frédéric Beisson,  Michel Havaux

SEPALLATA-driven MADS transcription factor tetramerization is required for inner whorl floral organ development

 Veronique Genevieve Hugouvieux,  Romain Blanc-Mathieu,  Michel Paul,  Aline Janeau,  Xiaocai Xu, Jeremy Lucas, Xuelei Lai, Antonin Galien,  Wenhao Yan, Max H Nanao,  Kerstin Kaufmann,  Francois Parcy,  Chloë Zubieta

Altered methionine metabolism impacts phenylpropanoid production and plant development in Arabidopsis thaliana

Doosan Shin, Veronica C Perez, Gabriella K Dickinson, Haohao Zhao, Ru Dai, Breanna M Tomiczek, Keun Ho Cho, Ning Zhu, Jin Koh, Alexander Grenning, Jeongim Kim

ROP GTPase regulates polarised cell growth and cell division orientation during tissue development and organogenesis in Marchantia polymorpha

 Hugh Mulvey,  Liam Dolan

| Evo-devo

Dynamic cell differentiation in multicellularity with specialized cell types

 Yuanxiao Gao,  Román Zapién-Campos, Arne Traulsen

Identifying candidate de novo genes expressed in the somatic female reproductive tract of Drosophila melanogaster

Kaelina D. Lombardo, Hayley K. Sheehy, Julie M. Cridland, David J. Begun

Phenotypic innovation in one tooth induced concerted developmental evolution in another

 Marie Sémon, Klara Steklikova, Marion Mouginot, Manon Peltier, Philippe Veber, Laurent Guéguen,  Sophie Pantalacci

Balancing selection at a wing pattern locus is associated with major shifts in genome-wide patterns of diversity and gene flow

María Ángeles Rodríguez de Cara,  Paul Jay,  Quentin Rougemont, Mathieu Chouteau, Annabel Whibley, Barbara Huber, Florence Piron-Prunier, Renato Rogner Ramos, André V. L. Freitas, Camilo Salazar, Karina Lucas Silva-Brandão, Tatiana Teixeira Torres,  Mathieu Joron

Cytoplasmic polyadenylation is an ancestral hallmark of early development in animals

 Labib Rouhana,  Allison Edgar,  Fredrik Hugosson, Valeria Dountcheva, Mark Q. Martindale,  Joseph F. Ryan

Ascidian cells with traits of neural crest and tailbud cells of vertebrates

Tasuku Ishida,  Yutaka Satou

Using developmental rules to align microevolution with macroevolution

 Fabio Andrade Machado,  Carrie S. Mongle, Graham Slater,  Anna Penna,  Anna Wisniewski, Anna Soffin, Vitor Dutra,  Josef C. Uyeda

Plasticity-led evolution as an intrinsic property of developmental gene regulatory networks

 Akira R. Kinjo,  Eden Tian Hwa Ng

Evolutionary conservation of embryonic DNA methylome remodelling in distantly related teleost species

Samuel E. Ross, Javier Vázquez-Marín, Krista R.B. Gert, Álvaro González-Rajal,  Marcel E. Dinger,  Andrea Pauli,  Juan Ramon Martínez-Morales,  Ozren Bogdanovic

Using developmental rules to align microevolution with macroevolution

 Fabio Andrade Machado,  Carrie S. Mongle, Graham Slater,  Anna Penna,  Anna Wisniewski, Anna Soffin, Vitor Dutra,  Josef C. Uyeda

Cell Biology

Tudor domain containing protein 5-like (Tdrd5l) identifies a novel germline body and regulates maternal RNAs during oogenesis

 Caitlin Pozmanter, Leif Benner, Sydney Kelly,  Harrison Curnutte,  Mark Van Doren

Neuronal IL-17 controls C. elegans developmental diapause through CEP-1/p53

Abhishiktha Godthi, Sehee Min, Srijit Das, Johnny Cruz-Corchado, Andrew Deonarine, Kara Misel-Wuchter,  Priya D. Issuree,  Veena Prahlad

Phosphorylation of 53BP1 by ATM enforce neurodevelopmental programs in cortical organoids

Bitna Lim, Mohamed Nadhir Djekidel,  Yurika Matsui, Seunghyun Jung, Zuo-Fei Yuan, Xusheng Wang, Xiaoyang Yang, Abbas Shirinifard Pilehroud, Haitao Pan, Fang Wang, Shondra Pruett-Miller, Kanisha Kavdia, Vishwajeeth Pagala, Yiping Fan,  Junmin Peng, Beisi Xu, Jamy C. Peng

Piezo1-dependent regulation of pericyte proliferation by blood flow during brain vascular development

Huaxing Zi, Xiaolan Peng, Jianbin Cao, Jiwen Bu, Jiulin Du, Jia Li

Gap junction-dependent amino acid transfer promotes germ cell growth

Caroline Vachias, Camille Tourlonias, Louis Grelee, Nathalie Gueguen,  Yoan Renaud, Graziella Richard, Parvathy Venugopal,  Pierre Pouchin,  Emilie Brasset,  Vincent Mirouse

The cellular basis of feeding-dependent body size plasticity in sea anemones

 Kathrin Garschall, Belen Garcia-Pascual,  Eudald Pascual-Carreras, Daria Filimonova,  Annika Guse,  Iain G. Johnston,  Patrick R.H. Steinmetz

Chimeric PRMT6 protein produced by an endogenous retrovirus promoter regulates cell fate decision in mouse preimplantation embryos

Shinnosuke Honda, Maho Hatamura, Yuri Kunimoto, Shuntaro Ikeda, Naojiro Minami

Luteinizing hormone stimulates ingression of granulosa cells within the mouse preovulatory follicle

 Corie M. Owen,  Laurinda A. Jaffe

A primary microcephaly-associated sas-6 mutation perturbs centrosome duplication, dendrite morphogenesis, and ciliogenesis in Caenorhabditis elegans

Mary Bergwell, Amy Smith, Ellie Smith, Carter Dierlam, Ramon Duran, Erin Haastrup, Rebekah Napier-Jameson, Rory Seidel, William Potter, Adam Norris,  Jyoti Iyer

Native extracellular matrix promotes human neuromuscular organoid morphogenesis and function

 Beatrice Auletta,  Lucia Rossi, Francesca Cecchinato, Gilda Barbato, Agnese Lauroja, Pietro Chiolerio, Giada Cecconi,  Edoardo Maghin,  Maria Easler,  Paolo Raffa,  Silvia Angiolillo, Wei Qin, Sonia Calabrò, Chiara Villa,  Onelia Gagliano,  Cecilia Laterza,  Davide Cacchiarelli,  Matilde Cescon,  Monica Giomo,  Yvan Torrente,  Camilla Luni,  Martina Piccoli,  Nicola Elvassore,  Anna Urciuolo

EMT induces cell-cycle-dependent changes of Rho GTPases and downstream effectors

Kamran Hosseini, Annika Frenzel,  Elisabeth Fischer-Friedrich

Tet Controls Axon Guidance in Early Brain Development through Glutamatergic Signaling

 Hiep Tran, Le Le, Badri Nath Singh, Joseph Kramer, Ruth Steward

Mapping of centriolar proteins onto the post-embryonic lineage of C. elegans

 Nils Kalbfuss, Antonin Berger, Pierre Gönczy

Cbl and Cbl-b Ubiquitin Ligases are Essential for Intestinal Epithelial Stem Cell Maintenance

Neha Zutshi,  Bhopal C. Mohapatra, Pinaki Mondal, Wei An, Benjamin T. Goetz, Shuo Wang, Sicong Li, Matthew D. Storck, David F. Mercer, Adrian R. Black, Sarah P. Thayer, Jennifer D. Black, Chi Lin,  Vimla Band,  Hamid Band

Modelling

The salt-and-pepper pattern in mouse blastocysts is compatible with signalling beyond the nearest neighbours

 Sabine C. Fischer,  Simon Schardt,  Joaquín Lilao-Garzón,  Silvia Muñoz Descalzo

Turing pattern formation in reaction-cross-diffusion systems with a bilayer geometry

 Antoine Diez,  Andrew L. Krause,  Philip K. Maini,  Eamonn A. Gaffney,  Sungrim Seirin-Lee

doi: https://doi.org/10.1101/2023.05.30.542795

How human-derived brain organoids are built differently from brain organoids derived of genetically-close relatives: A multi-scale hypothesis

Tao Zhang, Sarthak Gupta,  Madeline A. Lancaster, J. M. Schwarz

Self-organization of microtubules: complexity analysis of emergent patterns

Nikita Frolov, Bram Bijnens, Daniel Ruiz-Reynés, Lendert Gelens

Metabolic Regulatory Network Kinetic Modeling with Multiple Isotopic Tracers for iPSCs

Keqi Wang, Wei Xie, Sarah W. Harcum

A geometrical perspective on development

Archishman Raju, Eric D. Siggia

Tools & Resources

Gene Expression Detection in Developing Mouse Tissue Using In Situ Hybridization and µCT Imaging

 Vilma Väänänen,  Mona M. Christensen,  Heikki Suhonen,  Jukka Jernvall

Trans-scale live imaging of an E5.5 mouse embryo using incubator-type dual-axes light-sheet microscopy

Go Shioi, Tomonobu M Watanabe, Junichi Kaneshiro,  Yusuke Azuma,  Shuichi Onami

Unraveling cellular complexity with unlimited multiplexed super-resolution imaging

 Florian Schueder,  Felix Rivera-Molina,  Maohan Su,  Phylicia Kidd, James E Rothman,  Derek Toomre,  Joerg Bewersdorf

Atlas of Plasmodium falciparum intraerythrocytic development using expansion microscopy

 Benjamin Liffner,  Ana Karla Cepeda Diaz,  James Blauwkamp,  David Anaguano,  Sonja Frölich,  Vasant Muralidharan,  Danny W. Wilson,  Jeffrey Dvorin,  Sabrina Absalon

MSCProfiler: An image processing workflow to investigate Mesenchymal Stem Cell heterogeneity using imaging flow cytometry data

 A. Gupta, S. Kausar, L. Balasubramanian,  U. Chakraborty

MSCProfiler: An image processing workflow to investigate Mesenchymal Stem Cell heterogeneity using imaging flow cytometry data.

 Ayona Gupta, Safia Kousar Shaik, Lakshmi Balasubramanian,  Uttara Chakraborty

Gosha: a database of organisms with defined optimal growth temperatures

 Karla Helena-Bueno,  Charlotte R. Brown,  Sergey Melnikov

Automated counting of Drosophila imaginal disc cell nuclei

Pablo Sanchez Bosch, Jeffrey D. Axelrod

(No Ratings Yet)
Loading...