November in preprints
Posted by the Node, on 15 December 2021
Welcome to our monthly trawl for developmental biology (and related) preprints.
The preprints this month are hosted on bioRxiv, arXiv and preprints.org – use these links to get to the section you want.
- Patterning & signalling
- Morphogenesis & mechanics
- Genes & genomes
- Stem cells, regeneration & disease modelling
- Plant development
- Evo-devo
Developmental biology
| Patterning & signalling
An RNA-based feed-forward mechanism ensures motor switching in oskar mRNA transport
Imre Gáspár, Ly Jane Phea, Mark A. McClintock, Simone Heber, Simon L. Bullock, Anne Ephrussi
Quantitative imaging in whole-mount zebrafish embryos traces morphogen gradient maintenance and noise propagation in BMP signaling
Xu Wang, Linlin Li, Ye Bu, Yixuan Liu, Tzu-Ching Wu, David M. Umulis
The Drosophila RNA binding protein Nab2 patterns dendritic arbors and axons via the planar cell polarity pathway
Edwin B. Corgiat, Sara M. List, J. Christopher Rounds, Dehong Yu, Ping Chen, Anita H. Corbett, Kenneth H. Moberg
Netrins and receptors control Drosophila optic lobe organization and transmedullary neuron axon targeting
Yu Zhang, Scott Lowe, Xin Li
Target of Rapamycin drives unequal responses to essential amino acid depletion in egg laying
André N. Alves, Carla M. Sgrò, Matthew D. Piper, Christen K. Mirth
Live imaging YAP signaling in mouse embryo development
Bin Gu, Brian Bradshaw, Min Zhu, Yu Sun, Sevan Hopyan, Janet Rossant
The expression of essential selenoproteins during zebrafish development requires SECIS binding protein 2-like
Nora T. Kiledjian, Rushvi Shah, Michael B. Vetick, Paul R. Copeland
Adar1 deletion causes degeneration of exocrine pancreas via Mavs-dependent interferon signaling
Dhwani N. Rupani, Robert W. Cowan, Fredrik I. Thege, Vidhi Chandra, Sonja M. Wörmann, Hajar Rajaei, Prerna Malaney, Olivereen Le Roux, Sara L. Manning, Jack Hashem, Jennifer Bailey-Lundberg, Florencia McAllister, Andrew D. Rhim
Fendrr synergizes with Wnt signalling to regulate fibrosis related genes during lung development
Tamer Ali, Sandra Rogala, Maria-Theodora Melissari, Sandra Währisch, Bernhard G Herrmann, Phillip Grote
A microRNA cluster downstream of the selector gene Fezf2 coordinates fate specification with dendritic branching in cortical neurons
Asha Iyer, Verl B Siththanandan, Victoria Lu, Ramesh Nair, Lee O. Vaasjo, Maria J Galazo, Suzanne Tharin
A life cycle alteration can correct molting defects in Caenorhabditis elegans
Shaonil Binti, Rosa V. Melinda, Braveen B. Joseph, Phil Edeen, Sam D. Miller, David S. Fay
Mechanisms underlying microglial colonization of developing neural retina in zebrafish
Nishtha Ranawat, Ichiro Masai
A comprehensive series of temporal transcription factors in the fly visual system
Nikolaos Konstantinides, Anthony M. Rossi, Aristides Escobar, Liébaut Dudragne, Yen-Chung Chen, Thinh Tran, Azalia Martinez Jaimes, Mehmet Neset Özel, Félix Simon, Zhiping Shao, Nadejda M. Tsankova, John F. Fullard, Uwe Walldorf, Panos Roussos, Claude Desplan
Live imaging YAP signaling in mouse embryo development
Bin Gu, Brian Bradshaw, Min Zhu, Yu Sun, Sevan Hopyan, Janet Rossant
TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling
Sushama Sivakumar, Shutao Qi, Ningyan Cheng, Adwait A. Sathe, Mohammed Kanchwala, Ashwani Kumar, Bret M. Evers, Chao Xing, Hongtao Yu
TGFβ signaling is required for sclerotome resegmentation during development of the spinal column in Gallus gallus
Sade W. Clayton, Ronisha McCardell, Rosa Serra
A neural progenitor mitotic wave is required for asynchronous axon outgrowth and morphology
Jérôme Lacoste, Hédi Soula, Angélique Burg, Agnès Audibert, Pénélope Darnat, Michel Gho, Sophie Louvet-Vallée
Selective YAP activation in Procr cells is essential for ovarian stem/progenitor expansion and epithelium repair
Jingqiang Wang, Lingli He, Zhiyao Xie, Wentao Yu, Lanyue Bai, Zuoyun Wang, Yi Lu, Chunye Liu, Junfen Fu, Lei Zhang, Yi Arial Zeng
Omics profiling identifies MAPK/ERK pathway as a gatekeeper of nephron progenitor metabolism
Hyuk Nam Kwon, Kristen Kurtzeborn, Xing Jin, Abigail Loh, Nathalie Escande-Beillard, Bruno Reversade, Sunghyouk Park, Satu Kuure
How do avian embryos resume development following diapause? A new role for TGF-β in regulating pluripotency-related genes
Narayan Pokhrel, Olga Genin, Dalit Sela-Donenfeld, Yuval Cinnamon
A non-transcriptional function of Yap orchestrates the DNA replication program
Rodrigo Meléndez García, Olivier Haccard, Albert Chesneau, Hemalatha Narassimprakash, Jérôme E Roger, Muriel Perron, Kathrin Marheineke, Odile Bronchain
Pre-implantation mouse embryo movement under hormonally altered conditions
Hannah Lufkin, Diana Flores, Zachary Raider, Manoj Madhavan, Madeline Dawson, Anna Coronel, Dhruv Sharma, Ripla Arora
STAT3 and HIF1α cooperatively mediate the transcriptional and physiological responses to hypoxia
Alberto Dinarello, Riccardo Massimiliano Betto, Chiara Cioccarelli, Linda Diamante, Giacomo Meneghetti, Margherita Peron, Annachiara Tesoriere, Claudio Laquatra, Natascia Tiso, Graziano Martello, Francesco Argenton
CLASS-II KNOX genes coordinate spatial and temporal patterns of the tomato ripening
Alexandra Keren-Keiserman, Amit Shtern, Daniel Chalupowicz, Chihiro Furumizu, John Paul Alvarez, Ziva Amsalem, Tzahi Arazi, Sharon Tuvia-Alkalai, Idan Efroni, Elazar Fallik, Alexander Goldshmidt
Connexinplexity: The spatial and temporal expression of connexin genes during vertebrate organogenesis
Rachel M. Lukowicz-Bedford, Dylan R. Farnsworth, Adam C. Miller
PDFGRα+ Stromal Cells Promote Salivary Gland Proacinar Differentiation Through FGF2-dependent BMP7 Signaling
Nicholas Moskwa, Ayma Mahmood, Deirdre A. Nelson, Amber L. Altrieth, Paolo Forni, Melinda Larsen
GPI-anchored FGF directs cytoneme-mediated bidirectional signaling to self-regulate tissue-specific dispersion
Lijuan Du, Alex Sohr, Yujia Li, Sougata Roy
Mechanisms underlying the cooperation between loss of epithelial polarity and Notch signaling during neoplastic growth in Drosophila
Rémi Logeay, Charles Géminard, Patrice Lassus, Miriam Rodríguez-Vázquez, Diala Kantar, Lisa Héron-Milhavet, Bettina Fischer, Sarah J. Bray, Jacques Colinge, Alexandre Djiane
Using light-sheet microscopy to study spontaneous activity in the developing lateral-line system
Qiuxiang Zhang, Katie Kindt
SELENOT deficiency alters projection neuron migration during corticogenesis in mice
Emmanuelle Carpentier, Anthony Falluel-Morel, Lisa Brunet, Magalie Bénard, David Godefroy, Loubna Boukhzar, Arnaud Arabo, Youssef Anouar
SRSF3 is a key regulator of epicardial formation
Irina-Elena Lupu, Andia N. Redpath, Nicola Smart
Mural cell SRF controls pericyte migration, vessel patterning and blood flow
Michael Martin Orlich, Rodrigo Diéguez-Hurtado, Regine Muehlfriedel, Vithiyanjali Sothilingam, Hartwig Wolburg, Cansu Ebru Oender, Pascal Woelffing, Christer Betsholtz, Konstantin Gaengel, Mathias Seeliger, Ralf H. Adams, Alfred Nordheim
Charting ESCRT function reveals distinct and non-compensatory roles in blood progenitor maintenance and lineage choice in Drosophila
Arindam Ray, Yashashwinee Rai, Maneesha S Inamdar
Reemployment of Kupffer’s vesicle cells into axial and paraxial mesoderm via transdifferentiation
Takafumi Ikeda, Kiichi Inamori, Toru Kawanishi, Hiroyuki Takeda
Retinoid-X Receptor Agonists Increase Thyroid Hormone Competence in Lower Jaw Remodeling of Pre-Metamorphic Xenopus laevis tadpoles
Brenda J. Mengeling, Lara F. Vetter, J. David Furlow
ESR2 regulates indian hedgehog signaling in neonatal rat ovary
Iman Dilower, V. Praveen Chakravarthi, Eun B. Lee, Subhra Ghosh, Shaon Borosha, Richita Roy, Saeed Masumi, Anohita Paul, Hindole Ghosh, Michael W. Wolfe, M. A. Karim Rumi
Ikaros family proteins regulate developmental windows in the mouse retina through convergent and divergent transcriptional programs
Awais Javed, Pierre Mattar, Allie Cui, Michel Cayouette
Maternal parity affects Day 8 embryo gene expression in old mares
Emilie Derisoud, Luc Jouneau, Clothilde Gourtay, Anne Margat, Catherine Archilla, Yan Jaszczyszyn, Rachel Legendre, Nathalie Daniel, Nathalie Peynot, Michèle Dahirel, Laurie Briot, Frédéric De Geoffroy, Véronique Duranthon, Pascale Chavatte-Palmer
Cell-state transitions and collective cell movement generate an endoderm-like region in gastruloids
Ali Hashmi, Sham Tlili, Pierre Perrin, Alfonso Martinez-Arias, Pierre-François Lenne
The molecular logic of synaptic wiring at the single cell level
Jessica Velten, Rashi Agarwal, Patrick van Nierop, Katrin Domsch, Lena Bognar, Malte Paulsen, Lars Velten, Ingrid Lohmann
Coupling adipose tissue architecture and metabolism via cytoophidia
Jingnan Liu, Yuanbing Zhang, Youfang Zhou, Qiao-Qi Wang, Kang Ding, Suwen Zhao, Pengfei Lu, Ji-Long Liu
From the formation of embryonic appendages to the color of wings: Conserved and novel roles of aristaless1 in butterfly development
Erick X. Bayala, Nicholas VanKuren, Darli Massardo, Marcus Kronforst
CTP synthase does not form cytoophidia in Drosophila interfollicular stalks
Zheng Wu, Ji-Long Liu
Neighbor-specific gene expression revealed from physically interacting cells during mouse embryonic development
Junil Kim, Michaela Mrugala Rothová, Linbu Liao, Siyeon Rhee, Guangzheng Weng, Eyal David, Ido Amit, Morteza Chalabi Hajkarim, Joshua M. Brickman, Kyoung Jae Won
A Notch-dependent transcriptional mechanism controls expression of temporal patterning factors in Drosophila medulla
Alokananda Ray, Xin Li
Prdm16 and Notch functionally and physically interact during artery development
Manu Beerens, Jore Van Wauwe, Sander Craps, Margo Daems, KC Ashmita, Chris Finck, Shane Wright, Nicholas D. Leigh, Calum A. MacRae, Aernout Luttun
The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing
Jessica Kim, Masafumi Muraoka, Rieko Ajima, Hajime Okada, Atsushi Toyoda, Hiroshi Mori, Yumiko Saga
IGF1 Signaling in Temporomandibular Joint Fibrocartilage Stem Cells Regulates Cartilage Growth and Homeostasis in Mice
Ruiye Bi, Xueting Luo, Qianli Li, Peiran Li, Yi Fan, Binbin Ying, Songsong Zhu
| Morphogenesis & mechanics
Spontaneous rotations in epithelia as an interplay between cell polarity and RhoA activity at boundaries
S. Lo Vecchio, O. Pertz, M. Szopos, L. Navoret, D. Riveline
The roles of distinct Ca2+ signaling mediated by Piezo and inositol triphosphate receptor (IP3R) in the remodeling of E-cadherin during cell dissemination
Alejandra J.H. Cabrera, Barry M. Gumbiner, Young V. Kwon
Cell Wall Biochemistry Drives Pollen Tube Mechanics and Affects Growth Rate
Hannes Vogler, Gautam Munglani, Tohnyui Ndinyanka Fabrice, Christian Draeger, Jan T. Burri, Christof Eichenberger, J. Paul Knox, Jean Claude Mollet, Bradley J. Nelson, Hans J. Herrmann, Christoph Ringli, Ueli Grossniklaus
A myosin chaperone, UNC-45A, is a novel regulator of intestinal epithelial barrier integrity and repair
Susana Lechuga, Alexander X. Cartagena-Rivera, Afshin Khan, Bert I. Crawford, Vani Narayanan, Daniel E. Conway, Jaakko Lehtimäki, Pekka Lappalainen, Florian Rieder, Michelle S. Longworth, Andrei I. Ivanov
Multifaceted control of E-cadherin dynamics by the Adaptor Protein Complex 1 during epithelial morphogenesis
Miguel Ramírez Moreno, Katy Boswell, Helen L. Casbolt, Natalia A. Bulgakova
Calcium fluctuations drive morphological patterning at the onset of Hydra morphogenesis
Erez Braun
Integration of vascular progenitors into functional blood vessels represents a novel mechanism of vascular growth
Sanjeeva Metikala, Michael Warkala, Satish Casie Chetty, Brendan Chestnut, Elizabeth Plender, Olivia Nester, Sophie Astrof, Saulius Sumanas
A lateral protrusion latticework connects neuroepithelial cells and is regulated during neurogenesis
Ioannis Kasioulis, Alwyn Dady, John James, Alan Prescott, Pamela A. Halley, Kate G. Storey
The C. elegans gonadal sheath Sh1 cells extend asymmetrically over a differentiating germ cell population in the proliferative zone
Xin Li, Noor Singh, Camille Miller, India Washington, Bintou Sosseh, Kacy Lynn Gordon
Optogenetic dissection of the roles of actomyosin in the mechanics underlying tissue fluidity
R. Marisol Herrera-Perez, Christian Cupo, Cole Allan, Alicia B. Dagle, Karen E. Kasza
Visceral organ morphogenesis via calcium-patterned muscle contractions
Noah P. Mitchell, Dillon Cislo, Suraj Shankar, Yuzheng Lin, Boris I. Shraiman, Sebastian J. Streichan
Cell cycle difference creates cortical tension difference that separates germ layer fates
Naohito Takatori, Yuuya Tachiki
Morphological aspects of opossum (Didelphis aurita) pancreas during intramarsupial development
Priscila Izabel Santos de Tótaro, Tarcísio De Souza Duarte, Clóvis Andrade Neves, Cláudio Cesar Fonseca, Silene Souza Rodrigues Sartori
Esrrγa regulates nephron development and ciliogenesis by controlling prostaglandin synthesis and cooperation with Ppargc1a
Hannah M. Wesselman, Ana L. Flores-Mireles, Rebecca A. Wingert
Competition for endothelial cell polarity drives vascular morphogenesis
Pedro Barbacena, Maria Dominguez-Cejudo, Catarina G. Fonseca, Manuel Gómez-González, Laura M. Faure, Georgia Zarkada, Andreia A. Pena, Anna Pezzarossa, Daniela Ramalho, Ylenia Giarratano, Marie Ouarné, David Barata, Isabela Fortunato, Lenka H. Misiková, Ian Mauldin, Yulia Carvalho, Xavier Trepat, Pere Roca-Cusachs, Anne Eichmann, Miguel O. Bernabeu, Cláudio A. Franco
Vertebrate hemicentin-1 interacts physically and genetically with nidogen-2
Jin-Li Zhang, Stefania Richetti, Thomas Ramezani, Daniela Welcker, Steffen Lütke, Hans-Martin Pogoda, Julia Hatzold, Frank Zaucke, Douglas R. Keene, Wilhelm Bloch, Gerhard Sengle, Matthias Hammerschmidt
Tetraspanin Cd9b and Cxcl12a/Cxcr4b have a synergistic effect on the control of collective cell migration
KS Marsay, S Greaves, H Mahabaleshwar, CM Ho, H Roehl, PN Monk, T. J. Carney, LJ Partridge
The developing kidney actively negotiates geometric packing conflicts to avoid defects
Louis S. Prahl, John M. Viola, Jiageng Liu, Alex J. Hughes
An interplay between cellular growth and atypical fusion defines morphogenesis of a modular glial niche
Maria Alexandra Rujano, David Briand, Bojana Ðelić, Pauline Spéder
Local mechanical stimuli shape tissue growth in vertebrate joint morphogenesis
Ester Comellas, Johanna E Farkas, Giona Kleinberg, Katlyn Lloyd, Thomas Mueller, Timothy J Duerr, Jose J Muñoz, James R Monaghan, Sandra J Shefelbine
Patterned mechanical feedback establishes a global myosin gradient
Hannah J. Gustafson, Nikolas Claussen, Stefano De Renzis, Sebastian J. Streichan
Tissue-specific inhibition of protein sumoylation uncovers diverse SUMO functions during C. elegans vulval development
Aleksandra Fergin, Gabriel Boesch, Nadja R. Greter, Simon Berger, Alex Hajnal
Spatiotemporal expression of regulatory kinases directs the transition from mitosis to cellular morphogenesis
Shuo Yang, Jennifer McAdow, Yingqiu Du, Jennifer Trigg, Paul H. Taghert, Aaron N. Johnson
Effective mechanical potential of cell–cell interaction explains basic structures of three-dimensional morphogenesis
Hiroshi Koyama, Hisashi Okumura, Atsushi M. Ito, Tetsuhisa Otani, Kazuyuki Nakamura, Kagayaki Kato, Toshihiko Fujimori
Mechanics of cell integration in vivo
Guilherme B. Ventura, Aboutaleb Amiri, Raghavan Thiagarajan, Mari Tolonen, Amin Doostmohammadi, Jakub Sedzinski
| Genes & genomes
Interpreting ruminant specific conserved non-coding elements by developmental gene regulatory network
Xiangyu Pan, Zhaoxia Ma, Xinqi Sun, Hui Li, Tingting Zhang, Chen Zhao, Nini Wang, Rasmus Heller, Wing Hung Wong, Wen Wang, Yu Jiang, Yong Wang
Mitochondrial DNA variants segregate during human preimplantation development into genetically different cell lineages that are maintained postnatally
Joke Mertens, Marius Regin, Neelke De Munck, Edouard Couvreu de Deckersberg, Florence Belva, Karen Sermon, Herman Tournaye, Christophe Blockeel, Hilde Van de Velde, Claudia Spits
Nucleolar-based Dux repression is essential for 2-cell stage exit
Sheila Q. Xie, Bryony J. Leeke, Chad Whidling, Ryan T. Wagner, Ferran Garcia-Llagostera, Paul Chammas, Nathan T-F. Cheung, Dirk Dormann, Michael T. McManus, Michelle Percharde
Cellular remodeling and JAK inhibition promote zygotic gene expression in the Ciona germline
Naoyuki Ohta, Lionel Christiaen
A feedback loop between heterochromatin and the nucleopore complex controls germ-cell to oocyte transition during Drosophila oogenesis
Kahini Sarkar, Noor M Kotb, Alex Lemus, Elliot T Martin, Alicia McCarthy, Justin Camacho, Ayman Iqbal, Alex M. Valm, Morgan A Sammons, Prashanth Rangan
An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype
Kathleen C. Keough, Parisha P. Shah, Ketrin Gjoni, Garrett T. Santini, Nadeera M. Wickramasinghe, Carolyn E. Dundes, Ashley Karnay, Angela Chen, Rachel E.A. Salomon, Patrick J. Walsh, Son C. Nguyen, Sean Whalen, Eric F. Joyce, Kyle M. Loh, Nicole Dubois, Katherine S. Pollard, Rajan Jain
ASC proneural transcription factors mediate the timely initiation of the neural program during neuroectodermal to neuroblast transition ensuring progeny fidelity
Vasiliki Theodorou, Aikaterini Stefanaki, Minas Drakos, Dafne Triantafyllou, Christos Delidakis
Comprehensive identification of fetal cis-regulatory elements in the human genome by single-cell multi-omics analysis
Hao Yu, Na Ai, Ping Peng, Yuwen Ke, Xuepeng Chen, Yun Li, Ting Zhao, Shan Jiang, Jiang Liu, Lan Jiang
Pan-primate DNA methylation clocks
Steve Horvath, Amin Haghani, Joseph A. Zoller, Ake T. Lu, Jason Ernst, Matteo Pellegrini, Anna J. Jasinska, Julie A. Mattison, Adam B. Salmon, Ken Raj, Markus Horvath, Kimberly C. Paul, Beate R. Ritz, Todd R. Robeck, Maria Spriggs, Erin E. Ehmke, Susan Jenkins, Cun Li, Peter W. Nathanielsz
Trim41 is essential for preventing X chromosome chaotic synapsis in male mice
Seiya Oura, Toshiaki Hino, Takashi Satoh, Taichi Noda, Takayuki Koyano, Ayako Isotani, Makoto Matsuyama, Shizuo Akira, Kei-ichiro Ishiguro, Masahito Ikawa
Reciprocal zebrafish-medaka hybrids reveal maternal control of zygotic genome activation timing
Krista R. Gert, Luis Enrique Cabrera Quio, Maria Novatchkova, Yixuan Guo, Bradley R. Cairns, Andrea Pauli
Maternally-inherited anti-sense piRNAs antagonize transposon expression in teleost embryos
Yixuan Guo, Krista R. Gert, Svetlana Lebedeva, Magdalena E. Potok, Candice L. Wike, Edward J. Grow, René F. Ketting, Andrea Pauli, Bradley R. Cairns
STAG2 promotes the myelination transcriptional program in oligodendrocytes
Ningyan Cheng, Mohammed Kanchwala, Bret M. Evers, Chao Xing, Hongtao Yu
The Ets protein Pointed P1 represses Asense expression in type II neuroblasts by activating Tailless
Rui Chen, Xiaobing Deng, Sijun Zhu
Parental genomes segregate into different blastomeres during multipolar zygotic divisions leading to mixoploid and chimeric blastocysts
Tine De Coster, Heleen Masset, Olga Tšuiko, Maaike Catteeuw, Nicolas Dierckxsens, Sophie Debrock, Karen Peeraer, Katrien Smits, Ann Van Soom, Joris Robert Vermeesch
Identification and characterization of BEND2 as a novel and key regulator of meiosis during mouse spermatogenesis
Longfei Ma, Dan Xie, Xiwen Lin, Hengyu Nie, Jian Chen, Chenxu Gao, Shuguang Duo, Chunsheng Han
Loss of histone methyltransferase SETD1B in oogenesis results in the redistribution of genomic histone 3 lysine 4 trimethylation
Courtney W. Hanna, Jiahao Huang, Christian Belton, Susanne Reinhardt, Andreas Dahl, Simon Andrews, A. Francis Stewart, Andrea Kranz, Gavin Kelsey
Feedforward regulatory logic underlies robustness of the specification-to-differentiation transition and fidelity of terminal cell fate during C. elegans endoderm development
Chee Kiang Ewe, Erica M. Sommermann, Josh Kenchel, Sagen E. Flowers, Morris F. Maduro, Joel H. Rothman
Interchromosomal interaction of homologous Stat92E alleles regulates transcriptional switch during stem-cell differentiation
Matthew Antel, Madona Masoud, Romir Raj, Ziwei Pan, Sheng Li, Barbara G. Mellone, Mayu Inaba
Cellular remodeling and JAK inhibition promote zygotic gene expression in the Ciona germline
Naoyuki Ohta, Lionel Christiaen
Defining the Transcriptional and Epigenetic Basis of Organotypic Endothelial Diversity in the Developing and Adult Mouse
Manuel E. Cantu Gutierrez, Matthew C. Hill, Gabrielle Largoza, James F. Martin, Joshua D. Wythe
Sperm Histone H3 Lysine 4 tri-methylation serves as a metabolic sensor of paternal obesity and is associated with the inheritance of metabolic dysfunction
Anne-Sophie Pepin, Christine Lafleur, Romain Lambrot, Vanessa Dumeaux, Sarah Kimmins
The distinct effects of MEK and GSK3 inhibition upon the methylome and transcriptome of mouse embryonic stem cells
Julia Spindel, Christel Krueger, Felix Krueger, Evangelia K. Papachristou, Kamal Kishore, Clive S. D’Santos, Wolf Reik
Investigation of Human Endogenous Retrovirus-K (ERVK) Expression and Function in Normal Placentation and Preterm Pregnancy
Jimi L. Rosenkrantz, Michael Martinez, Adithi Mahankali, Lucia Carbone, Shawn L. Chavez
Genome-wide mapping of histone modification H3K4me3 in bovine oocytes and early embryos
Yanna Dang, Lei Luo, Yan Shi, Shuang Li, Shaohua Wang, Kun Zhang
Mouse CHD4-NURD is required for neonatal spermatogonia survival and normal gonad development
Rodrigo O. de Castro, Luciana Previato, Agustin Carbajal, Victor Goitea, Courtney T. Griffin, Roberto J. Pezza
Young transposable elements rewired gene regulatory networks in human and chimpanzee hippocampal intermediate progenitors
Sruti Patoori, Samantha Barnada, Marco Trizzino
TFAP2 paralogs pioneer chromatin access for MITF and directly inhibit genes associated with cell migration
Colin Kenny, Ramile Dilshat, Hannah Seberg, Eric Van Otterloo, Gregory Bonde, Annika Helverson, Eiríkur Steingrímsson, Robert A. Cornell
Non-random sister chromatid segregation mediates rDNA copy number maintenance in Drosophila
George J. Watase, Yukiko M. Yamashita
Intron dynamics reveal principles of gene regulation during the maternal-to-zygotic transition
Kent Riemondy, Jesslyn C. Henriksen, Olivia S. Rissland
Critical role of H3K27 methylation in cell fate determination of two cell lineages in male gametophyte
Xiaorong Huang, Meng-Xiang Sun
Dynamics of sex-biased gene expression during development in the stick insect Timema californicum
Djordjevic Jelisaveta, Dumas Zoé, Robinson-Rechavi Marc, Schwander Tanja, Parker Darren James
A Unified Genomic Mechanism of Cell-Fate Change
Masa Tsuchiya, Alessandro Giuliani, Giovanna Zimatore, Jekaterina Erenpreisa, Kenichi Yoshikawa
Analysis of transcriptional changes associated with pubertal development
Justyna Resztak, Jane Choe, Julong Wei, Rachel Bruinsma, Russell Houpt, Adnan Alazizi, Henriette E. Mair-Meijers, Richard B. Slatcher, Samuele Zilioli, Roger Pique-Regi, Francesca Luca
| Stem cells, regeneration & disease modelling
Identification and Characterization of Stem Cells in Mammalian Esophageal Stratified Squamous Epithelia
Yanan Yang, Guodong Deng, Lili Qiao, Hui Yuan, Xiaohong Yu, Lei Xu, Shih-Hsin Lu, Wei Jiang, Xiying Yu
Trisomy 21 induces pericentrosomal crowding disrupting early stages of primary ciliogenesis and mouse cerebellar development
Cayla E Jewett, Bailey L McCurdy, Eileen T O’Toole, Katherine S Given, Carrie H Lin, Valerie Olsen, Whitney Martin, Laura G Reinholdt, Joaquin M Espinosa, Kelly D Sullivan, Wendy B Macklin, Rytis Prekeris, Chad G Pearson
Pluripotency-Independent Induction of Human Trophoblast Stem Cells from Fibroblasts
Moriyah Naama, Ahmed Radwan, Valery Zayat, Shulamit Sebban, Moran Rahamim, Rachel Lasry, Mohammad Jaber, Ofra Sabag, Hazar Yassen, Dana Orzech, Areej Khatib, Silvina Epsztejn-Litman, Michal Novoselsky-Persky, Kirill Makedonski, Noy Deri, Debra Goldman-Wohl, Howard Cedar, Simcha Yagel, Rachel Eiges, Yosef Buganim
MTG16 (CBFA2T3) represses E protein-dependent transcription to regulate colonic secretory cell differentiation, epithelial regeneration, and tumorigenesis
Rachel E. Brown, Justin Jacobse, Shruti A. Anant, Koral M. Blunt, Bob Chen, Paige N. Vega, Chase T. Jones, Jennifer M. Pilat, Frank Revetta, Aidan H. Gorby, Kristy R. Stengel, Yash A. Choksi, Kimmo Palin, M. Blanca Piazuelo, M. Kay Washington, Ken S. Lau, Jeremy A. Goettel, Scott W. Hiebert, Sarah P. Short, Christopher S. Williams
MicroRNA-24-3p promotes skeletal muscle differentiation and regeneration by regulating HMGA1
Paromita Dey, Miles A. Soyer, Bijan K. Dey
Notch-dependent DNA cis-regulatory elements and their dose-dependent control of C. elegans stem cell self-renewal
Tina R Lynch, Mingyu Xue, Cazza W. Czerniak, ChangHwan Lee, Judith Kimble
Base editing in bovine embryos reveals a species-specific role of SOX2 in regulation of pluripotency
Lei Luo, Yan Shi, Huanan Wang, Zizengchen Wang, Yanna Dang, Shuang Li, Shaohua Wang, Kun Zhang
Transgenerational impact of aberrant inflammation in rat pregnancy
Takafumi Ushida, Tiziana Cotechini, Nicole Protopappas, Aline Atallah, Charlotte Collyer, Shannyn K. Macdonald-Goodfellow, M. Yat Tse, Louise M. Winn, Stephen C. Pang, Michael A. Adams, Maha Othman, Tomomi Kotani, Hiroaki Kajiyama, Charles H. Graham
Interchromosomal interaction of homologous Stat92E alleles regulates transcriptional switch during stem-cell differentiation
Matthew Antel, Madona Masoud, Romir Raj, Ziwei Pan, Sheng Li, Barbara G. Mellone, Mayu Inaba
Transcriptional evaluation of the ductus arteriosus at the single-cell level uncovers a requirement for vimentin for complete closure
Jocelynda Salvador, Gloria E. Hernandez, Feiyang Ma, Cyrus W. Abrahamson, Matteo Pellegrini, Robert Goldman, Karen M. Ridge, M. Luisa Iruela-Arispe
Oxytocin promotes epicardial cell activation and heart regeneration after cardiac injury
Aaron H. Wasserman, Yonatan R. Lewis-Israeli, Amanda R. Huang, McKenna D. Dooley, Allison L. Mitchell, Manigandan Venkatesan, Aitor Aguirre
Transcription factor induction of vascular blood stem cell niches in vivo
Elliott J. Hagedorn, Julie R. Perlin, Rebecca J. Freeman, Samuel J. Wattrus, Tianxiao Han, Clara Mao, Ji Wook Kim, Inés Fernández-Maestre, Madeleine L. Daily, Christopher D’Amato, Michael J. Fairchild, Raquel Riquelme, Brian Li, Dana A.V.E. Ragoonanan, Khaliun Enkhbayar, Emily L. Henault, Helen G. Wang, Shelby E. Redfield, Samantha H. Collins, Asher Lichtig, Song Yang, Yi Zhou, Balvir Kunar, Jesus Maria Gomez-Salinero, Thanh T. Dinh, Junliang Pan, Karoline Holler, Henry A. Feldman, Eugene C. Butcher, Alexander van Oudenaarden, Shahin Rafii, J. Philipp Junker, Leonard I. Zon
Impaired ability in visual-spatial attention in Chinese children with developmental dyslexia
Mengyu Tian, Runzhou Wang, Hong-Yan Bi
Chigno/CG11180 and SUMO are Chinmo-Interacting Proteins with a Role in Drosophila Testes Stem Cells
Leanna Rinehart, Wendy E. Stewart, Natalie Luffman, Matthew Wawersik, Oliver Kerscher
Coronary blood vessels from distinct origins converge to equivalent states during mouse and human development
Ragini Phansalkar, Josephine Krieger, Mingming Zhao, Sai Saroja Kolluru, Robert C. Jones, Stephen R Quake, Irving Weissman, Daniel Bernstein, Virginia D. Winn, Gaetano D’Amato, Kristy Red-Horse
Krüppel-like factor 4 is required for development and regeneration of germline and yolk cells from somatic stem cells in planarians
Melanie Issigonis, Akshada B. Redkar, Tania Rozario, Umair W. Khan, Rosa Mejia-Sanchez, Sylvain W. Lapan, Peter W. Reddien, Phillip A. Newmark
Somatic regulation of female germ cell regeneration and development in planarians
Umair W. Khan, Phillip A. Newmark
Highly efficient Runx1 enhancer eR1-mediated genetic engineering for fetal, child and adult hematopoietic stem cells
Cai Ping Koh, Avinash Govind Bahirvani, Chelsia Qiuxia Wang, Tomomasa Yokomizo, Cherry Ee Lin Ng, Linsen Du, Vinay Tergaonkar, Dominic Chih-Cheng Voon, Hiroki Hosoi, Takashi Sonoki, Mok Meng Huang Michelle, Akiko Niibori-Nambu, Yi Zhang, Archibald S. Perkins, Zakir Hossain, Daniel G. Tenen, Yoshiaki Ito, Byrappa Venkatesh, Motomi Osato
Systematic mapping of rRNA 2’-O methylation during frog development and involvement of the methyltransferase Fibrillarin in eye and craniofacial development in Xenopus laevis
Jonathan Delhermite, Lionel Tafforeau, Sunny Sharma, Virginie Marchand, Ludivine Wacheul, Ruben Lattuca, Simon Desiderio, Yuri Motorin, Eric Bellefroid, Denis L.J. Lafontaine
Over 400 million years of cooperation: Untangling the chondrocranium-dermatocranium connection
Susan M. Motch Perrine, M. Kathleen Pitirri, Emily L. Durham, Mizuho Kawasaki, Hao Zheng, Danny Z. Chen, Kazuhiko Kawasaki, Joan T. Richtsmeier
Transient grb10a Knockdown Permanently Alters Growth, Cardiometabolic Phenotype and the Transcriptome in Danio rerio
Bridget L Evans, Terence Garner, Chiara De Leonibus, Oliver H Wearing, Holly A Shiels, Adam F L Hurlstone, Peter E Clayton, Adam Stevens
Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism
Mírian Romitti, Barbara de Faria da Fonsecaa, Gilles Doumont, Pierre Gillotay, Adrien Tourneur, Sema Elif Eski, Gaetan Van Simaeys, Laura Chomette, Helene Lasolle, Olivier Monestier, Dominika Figini Kasprzyk, Vincent Detours, Sumeet Pal Singh, Serge Goldman, Samuel Refetoff, Sabine Costagliola
HSC-independent definitive hematopoietic cells persist into adult life
Michihiro Kobayashi, Haichao Wei, Takashi Yamanashi, David J Shih, Nathalia Azevedo Portilho, Samuel Cornelius, Noemi Valiente, Chika Nishida, Wenjin J Zheng, Joonsoo Kang, Jun Seita, Jia Qian Wu, Momoko Yoshimoto
Drosophila renal stem cells enhance fitness by delayed remodeling of adult Malpighian tubules
Chenhui Wang, Allan C. Spradling
Single cell profiling of Hofbauer cells and fetal brain microglia reveals shared programs and functions
Alexis M Ceasrine, Rebecca Batorsky, Lydia L. Shook, Sezen Kislal, Evan A. Bordt, Benjamin A. Devlin, Roy H. Perlis, Donna K. Slonim, Staci D. Bilbo, Andrea G. Edlow
Stem cell specific interferon stimulated gene expression is regulated by the formative pluripotency network through IRF1
Merrit Romeike, Stephanie Spach, Marie Huber, Songjie Feng, Gintautas Vainorius, Ulrich Elling, Christa Buecker
Chemical induction of gut β-like-cells by combined FoxO1/Notch inhibition as a glucose-lowering treatment for diabetes
Takumi Kitamoto, Yun-Kyoung Lee, Wendy M. McKimpson, Hitoshi Watanabe, Nishat Sultana, Wen Du, Jason Fan, Bryan Diaz, Hua V. Lin, Rudolph L. Leibel, Sandro Belvedere, Domenico Accili
A phenotypic rescue approach identifies lineage regionalization defects in a mouse model of DiGeorge syndrome
Gabriella Lania, Monica Franzese, Adachi Noritaka, Marchesa Bilio, Annalaura Russo, Erika D’Agostino, Claudia Angelini, Robert G. Kelly, Antonio Baldini
β-catenin perturbations control differentiation programs in mouse embryonic stem cells
Elisa Pedone, Mario Failli, Gennaro Gambardella, Rossella De Cegli, Antonella La Regina, Diego di Bernardo, Lucia Marucci
Circadian regulation of lung repair and regeneration
Amruta Naik, Kaitlyn Forrest, Yasmine Issah, Utham Valekunja, Akhilesh B Reddy, Elizabeth Hennessy, Thomas S. Brooks, Apoorva Babu, Mike Morley, Gregory R. Grant, Garret A. FitzGerald, Amita Sehgal, G. Scott Worthen, David B. Frank, Edward E Morrisey, Shaon Sengupta
Re-entry into mitosis and regeneration of intestinal stem cells through enteroblast dedifferentiation in Drosophila midguts
Aiguo Tian, Virginia Morejon, Sarah Kohoutek, Yi-Chun Huang, Wu-Min Deng, Jin Jiang
Simple and efficient differentiation of human iPSCs into contractible skeletal muscles for muscular disease modeling
Muhammad Irfanur Rashid, Takuji Ito, Daisuke Shimojo, Kanae Arimoto, Kazunari Onodera, Rina Okada, Takunori Nagashima, Kazuki Yamamoto, Zohora Khatun, Hideyuki Okano, Hidetoshi Sakurai, Kazunori Shimizu, Manabu Doyu, Yohei Okada
Directing iPSC Differentiation into iTenocytes using Combined Scleraxis Overexpression and Cyclic Loading
Angela Papalamprou, Victoria Yu, Angel Chen, Tina Stefanovic, Giselle Kaneda, Khosrowdad Salehi, Chloe Castaneda, Arkadiusz Gertych, Juliane D Glaeser, Dmitriy Sheyn
The IRE1/XBP1 signaling axis promotes skeletal muscle regeneration through a cell non-autonomous mechanism
Anirban Roy, Meiricris Tomaz da Silva, Raksha Bhat, Kyle R. Bohnert, Takao Iwawaki, Ashok Kumar
Single-cell Transcriptomic Analysis Reveals the Cellular Heterogeneity of Mesenchymal Stem Cells
Chen Zhang, Xueshuai Han, Jingkun Liu, Lei Chen, Ying Lei, Kunying Chen, Jia Si, Tian-yi Wang, Hui Zhou, Xiaoyun Zhao, Xiaohui Zhang, Yihua An, Yueying Li, Qian-fei Wang
| Plant development
Initiation of organ maturation and fruit ripening in grapevine is controlled by the CARPO-NAC transcription factor
Erica D’Incà, Chiara Foresti, Luis Orduña, Alessandra Amato, Elodie Vandelle, Antonio Santiago, Alessandro Botton, Stefano Cazzaniga, Edoardo Bertini, Mario Pezzotti, James Giovannoni, Julia Vrebalov, José Tomás Matus, Giovanni Battista Tornielli, Sara Zenoni
Jasmonic Acid coordinates with Light, Glucose and Auxin signalling in Regulating Branching Angle of Arabidopsis Lateral Roots
Manvi Sharma, Mohan Sharma, K Muhammed Jamsheer, Ashverya Laxmi
Dosage of duplicated and antifunctionalized homeobox proteins influences spikelet development in barley
Venkatasubbu Thirulogachandar, Geetha Govind, Götz Hensel, Sandip M. Kale, Markus Kuhlmann, Lennart Eschen-Lippold, Twan Rutten, Ravi Koppolu, Jeyaraman Rajaraman, Sudhakar Reddy Palakolanu, Christiane Seiler, Shun Sakuma, Murukarthick Jayakodi, Justin Lee, Jochen Kumlehn, Takao Komatsuda, Thorsten Schnurbusch, Nese Sreenivasulu
A vacuolar hexose transport is required for xylem development in the inflorescence stem of Arabidopsis
Emilie Aubry, Beate Hoffmann, Françoise Vilaine, Françoise Gilard, Patrick A.W. Klemens, Florence Guérard, Bertrand Gakière, H. Ekkehard Neuhaus, Catherine Bellini, Sylvie Dinant, Rozenn Le Hir
TWISTED DWARF1 regulates Arabidopsis stamen development by differential activation of ABCB-mediated auxin transport
Jie Liu, Roberta Ghelli, Maura Cardarelli, Markus Geisler
SCARECROW is deployed in distinct developmental contexts during rice and maize leaf development
Thomas. E. Hughes, Jane A. Langdale
The regeneration factors ERF114 and ERF115 act as transducers of mechanical cues to developmental pathways
Balkan Canher, Fien Lanssens, Ai Zhang, Anchal Bisht, Shamik Mazumdar, Jefri Heyman, Frauke Augstein, Sebastian Wolf, Annelie Carlsbecker, Charles W. Melnyk, Lieven De Veylder
The transcription factor AtHB23 modulates starch turnover for root development and plant survival under salinity
María Florencia Perotti, Agustín Lucas Arce, Federico Damián Ariel, Carlos María Figueroa, Raquel Lía Chan
The annotation and analysis of complex 3D plant organs using 3DCoordX
Athul Vijayan, Soeren Strauss, Rachele Tofanelli, Tejasvinee Atul Mody, Karen Lee, Miltos Tsiantis, Richard S. Smith, Kay Schneitz
CHIQUITA1 maintains temporal transition between proliferation and differentiation in Arabidopsis thaliana
Flavia Bossi, Benjamin Jin, Elena Lazarus, Heather Cartwright, Yanniv Dorone, Seung Y. Rhee
The dynamics of HD-ZIP III – ZPR protein interactions play essential roles in embryogenesis, meristem function and organ development
Anna Vitlin Gruber, Melissa Kosty, Yasaman Jami-Alahmadi, James A. Wohlschlegel, Jeff A. Long
| Evo-devo
Natural variation in the maternal and zygotic mRNA complements of the early embryo in Drosophila melanogaster
Anna A. Feitzinger, Anthony Le, Ammon Thompson, Mehnoor Haseeb, Mohan K. Murugesan, Austin M. Tang, Susan E. Lott
How to align arthropod legs
Heather S. Bruce
The Daphnia carapace and the origin of novel structures
Heather S. Bruce, Nipam H. Patel
Krüppel-like factor 4 is required for development and regeneration of germline and yolk cells from somatic stem cells in planarians
Melanie Issigonis, Akshada B. Redkar, Tania Rozario, Umair W. Khan, Rosa Mejia-Sanchez, Sylvain W. Lapan, Peter W. Reddien, Phillip A. Newmark
Cephalopod Retinal Development Shows Vertebrate-like Mechanisms of Neurogenesis
Francesca Napoli, Christina M. Daly, Stephanie Neal, Kyle J. McCulloch, Alexandra Zaloga, Alicia Liu, Kristen M. Koenig
A tripartite structure, the complex nuclear receptor element (cNRE), is a cis-regulatory module of viral origin required for atrial chamber preferential gene expression
Luana Nunes Santos, Ângela Maria da Souza Costa, Martin Nikolov, Allysson Coelho Sampaio, Frank E. Stockdale, Gang F Wangø, Hozana Andrade Castillo, Mariana Bortoletto Grizante, Stefanie Dudczig, Michelle Vasconcelos, Nadia Rosenthal, Patricia Regina Jusuf, Paulo de Oliveira, Tatiana Guimarães de Freitas Matos, William Nikovits Jr., Michael Schubert, Mirana Ramialison, José Xavier-Neto
An evolutionarily conserved cis-regulatory element of Nkx3.2 contributes to early jaw joint morphology in zebrafish
Jake Leyhr, Laura Waldmann, Beata Filipek-Górniok, Hanqing Zhang, Amin Allalou, Tatjana Haitina
Life Strategies in Placozoa
Daria Y. Romanova, Mikhail A. Nikitin, Sergey V. Shchenkov, Leonid L. Moroz
Cell Biology
A novel mechanism of bulk cytoplasmic transport by cortical dynein in Drosophila ovary
Wen Lu, Margot Lakonishok, Anna S. Serpinskaya, Vladimir I. Gelfand
Single-particle tracking of dynein identifies PP2A B55/SUR-6 as a cell cycle regulator of cortical force generation
Alan Edwards, John B. Linehan, Vincent Boudreau, Paul S. Maddox
Sequestration of LINE-1 in novel cytosolic bodies by MOV10 restricts retrotransposition
Rajika Arora, Maxime Bodak, Laura Penouty, Cindy Hackman, Constance Ciaudo
Arp2/3 complex activity is necessary for mouse ESC differentiation, times formative pluripotency, and enables lineage specification
Francesca M. Aloisio, Diane L. Barber
Separable mechanisms drive local and global polarity establishment in the C. elegans intestinal epithelium
Melissa A. Pickett, Maria D. Sallee, Victor F. Naturale, Deniz Akpinaroglu, Joo Lee, Kang Shen, Jessica L. Feldman
Placental structure, function and mitochondrial phenotype relate to fetal size and sex in mice
Esteban Salazar-Petres, Daniela Pereira Carvalho, Jorge Lopez-Tello, Amanda Nancy Sferruzzi-Perri
Tracheal tube fusion in Drosophila involves release of extracellular vesicles from multivesicular bodies
Carolina Camelo, Anna Körte, Thea Jacobs, Stefan Luschnig
Mouse oocytes develop in cysts with the help of nurse cells
Wanbao Niu, Allan C. Spradling
Ubiquitin ligases and a processive proteasome facilitate protein clearance during the oocyte-to-embryo transition in Caenorhabditis elegans
Caroline A. Spike, Tatsuya Tsukamoto, David Greenstein
Shaping the size of a neuronal lineage: the role of Imp and Syp RBPs in the precise elimination of neurons by apoptosis
Wenyue Guan, Mathilde Bouchet, Aurélien Darmas, Jonathan Enriquez
The sperm protein Spaca6 is essential for fertilization in zebrafish
Mirjam I. Binner, Anna Kogan, Karin Panser, Alexander Schleiffer, Victoria E. Deneke, Andrea Pauli
Tetraspanin Cd9b plays a role in fertility in zebrafish
S Greaves, KS Marsay, PN Monk, H Roehl, LJ Partridge
Pre-meiotic pairing of homologous chromosomes during Drosophila male meiosis
Thomas Rubin, Nicolas Macaisne, Ana Maria Vallés, Clara Guilleman, Isabelle Gaugué, Jean-René Huynh
CADHERIN mediated AMIS localisation
Xuan Liang, Antonia Weberling, Chun Yuan Hii, Magdalena Zernicka-Goetz, Clare E Buckley
Daughter centrioles assemble preferentially towards the nuclear envelope in Drosophila syncytial embryos
Neil H. J. Cunningham, Imène B. Bouhlel, Paul T. Conduit
Modelling
Modeling the mechanics of growing epithelia with a bilayer plate theory
Joseph Ackermann, Paul-Qiuyang Qu, Loïc LeGoff, Martine Ben Amar
Cells use molecular working memory to navigate in changing chemoattractant fields
Akhilesh Nandan, Abhishek Das, Robert Lott, Aneta Koseska
insideOutside: an accessible algorithm for classifying interior and exterior points, with applications in embryology
Stanley E. Strawbridge, Agata Kurowski, Elena Corujo-Simon, Alexander G. Fletcher, Jennifer Nichols
Scaling dictates the decoder structure
Jingxiang Shen, Feng Liu, Chao Tang
Reconstruction of dynamic regulatory networks reveals signaling-induced topology changes associated with germ layer specification
Emily Y. Su, Abby Spangler, Qin Bian, Jessica Y. Kasamoto, Patrick Cahan
Adhesion strength between cells regulate non-monotonic growth by a biomechanical feedback mechanism
Abdul N Malmi-Kakkada, Sumit Sinha, Xin Li, D. Thirumalai
Active morphogenesis of patterned epithelial shells
Diana Khoromskaia, Guillaume Salbreux
A continuum mathematical model of substrate-mediated tissue growth
Maud El-Hachem, Scott W McCue, Matthew J Simpson
Mechanochemical models for calcium waves in embryonic epithelia
Katerina Kaouri, Paul E. Méndez, Ricardo Ruiz-Baier
Global cell-cell communication enables spatial segregation of cells in organoids of the inner cell mass
Simon Schardt, Sabine C. Fischer
Interfacial friction dictates long-range force propagation in tissues
Yuting Lou, Takumi Kawaue, Ivan Yow, Yusuke Toyama, Jacques Prost, Tetsuya Hiraiwa
Reviews
Morphomics via Next-generation Electron Microscopy
Raku Son, Kenji Yamazawa, Akiko Oguchi, Mitsuo Suga, Masaru Tamura, Yasuhiro Murakawa, Satoshi Kume
Self-organization in embryonic development: myth and reality
Stuart A. Newman
From Single Cells to Flowers – Biological Complexity Driving Plant Reproductive Development
Isabel Schwarz , Manuel Neumann , Rosario Vega , Xiaocai Xu , Letizia Cornaro , Lucia Colombo, Teva Vernoux , Jian Xu , Sebastian Marquardt , Kerstin Kaufmann
Selective Drivers of Simple Multicellularity
Kai Tong , G. Ozan Bozdag , William C. Ratcliff
The Evolution of Hox Genes in Spiralia
Andreas Hejnol, Ludwik Gasiorowski , Jose-Maria Martin-Duran
Tools & Resources
MusMorph, a database of standardized mouse morphology data for morphometric meta-analyses
Jay Devine, Marta Vidal-García, Wei Liu, Amanda Neves, Lucas D. Lo Vercio, Rebecca M. Green, Heather A. Richbourg, Marta Marchini, Colton M. Unger, Audrey C. Nickle, Bethany Radford, Nathan M. Young, Paula N. Gonzalez, Robert E. Schuler, Alejandro Bugacov, Campbell Rolian, Christopher J. Percival, Trevor Williams, Lee Niswander, Anne L. Calof, Arthur D. Lander, Axel Visel, Frank R. Jirik, James M. Cheverud, Ophir Klein, Ramon Y. Birnbaum, Amy E. Merrill, Rebecca R. Ackermann, Daniel Graf, Myriam Hemberger, Wendy Dean, Nils D. Forkert, Stephen A. Murray, Henrik Westerberg, Ralph S. Marcucio, Benedikt Hallgrímsson
A toolkit to generate inducible and interconvertible Drosophila transgenes
Franz Wendler, Sangbin Park, Claire Hill, Alessia Galasso, Kathleen R. Chang, Iman Awan, Yulia Sudarikova, Mar Bustamante-Sequeiros, Sichen Liu, Ethan Sung, Gabrielle Aisabonoko, Seung K. Kim, Luis Alberto Baena-Lopez
Evaluation of CRISPR gene-editing tools in zebrafish
José M. Uribe-Salazar, Gulhan Kaya, Aadithya Sekar, KaeChandra Weyenberg, Cole Ingamells, Megan Y. Dennis
Self-organized emergence of hyaline cartilage in hiPSC-derived multi-tissue organoids
Manci Li, Juan E. Abrahante, Amanda Vegoe, Yi Wen Chai, Beth Lindborg, Ferenc Toth, Peter A. Larsen, Timothy D. O’Brien
A deep learning framework for quantitative analysis of actin microridges
Rajasekaran Bhavna, Mahendra Sonawane
Chromosome counting in the mouse zygote using low-invasive super-resolution live-cell imaging
Yu Hatano, Daisuke Mashiko, Mikiko Tokoro, Tatsuma Yao, Kazuo Yamagata
A powerful and versatile new fixation protocol for immunohistology and in situ hybridization that preserves delicate tissues in planaria
Carlos Guerrero-Hernández, Viraj Doddihal, Frederick G. Mann Jr., Alejandro Sánchez Alvarado
A method to quantitate maternal transcripts localized in sea urchin egg cortex by RT-qPCR with accurate normalization
Yulia O. Kipryushina, Mariia A. Maiorova, Konstantin V. Yakovlev
Robust temporal map of human in vitro myelopoiesis using single-cell genomics
Clara Alsinet, Maria Primo, Valentina Lorenzi, Andrew J Knights, Carmen Sancho-Serra, Jong-Eun Park, Beata S Wyspianska, David F Tough, Damiana Alvarez-Errico, Daniel J Gaffney, Roser Vento-Tormo
DeepProjection: Rapid and structure-specific projections of tissue sheets embedded in 3D microscopy stacks using deep learning
Daniel Haertter, Xiaolei Wang, Stephanie M. Fogerson, Nitya Ramkumar, Janice M. Crawford, Kenneth D. Poss, Stefano Di Talia, Daniel P. Kiehart, Christoph F. Schmidt
Paraxial mesoderm organoids model development of human somites
Christoph Budjan, Shichen Liu, Adrian Ranga, Senjuti Gayen, Olivier Pourquie, Sahand Hormoz
Single-cell Atlas Unveils Cellular Heterogeneity and Novel Markers in Human Neonatal and Adult Intervertebral Discs
Wensen Jiang, Juliane D. Glaeser, Khosrowdad Salehi, Giselle Kaneda, Pranav Mathkar, Anton Wagner, Ritchie Ho, Dmitriy Sheyn
Rapid and efficient adaptation of the dTAG system in mammalian development reveals stage specific requirements of NELF
Abderhman Abuhashem, Anna-Katerina Hadjantonakis
A single-cell transcriptome atlas of human early embryogenesis
Yichi Xu, Tengjiao Zhang, Qin Zhou, Mengzhu Hu, Yao Qi, Yifang Xue, Lihui Wang, Zhirong Bao, Weiyang Shi
Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary
Yulong Liu, Michelle E. Kossack, Matthew E. McFaul, Lana Christensen, Stefan Siebert, Sydney R. Wyatt, Caramai Kamei, Samuel Horst, Nayeli Arroyo, Iain Drummond, Celina E. Juliano, Bruce W. Draper
Spatial charting of single cell transcriptomes in tissues
Runmin Wei, Siyuan He, Shanshan Bai, Emi Sei, Min Hu, Alastair Thompson, Ken Chen, Savitri Krishnamurthy, Nicholas E. Navin
The Tabula Sapiens: a multiple organ single cell transcriptomic atlas of humans
The Tabula Sapiens Consortium, Stephen R Quake
When less is more – Endogenous tagging with TurboID increases the sensitivity of proximity labelling-based experiments
Alexander Stockhammer, Laila S. Benz, Christian Freund, Benno Kuropka, Francesca Bottanelli
Fast DNA-PAINT imaging using a deep neural network
Kaarjel K. Narayanasamy, Johanna V. Rahm, Siddharth Tourani, Mike Heilemann
Simultaneous multicolor DNA-PAINT without sequential fluid exchange using spectral demixing
Niclas Gimber, Sebastian Strauss, Ralf Jungmann, Jan Schmoranzer
Single organoid RNA-sequencing reveals high organoid-to-organoid variability
Kristin Gehling, Swati Parekh, Farina Schneider, Marcel Kirchner, Vangelis Kondylis, Chrysa Nikopoulou, Peter Tessarz
Stain-free Detection of Embryo Polarization using Deep Learning
Cheng Shen, Adiyant Lamba, Meng Zhu, Ray Zhang, Changhuei Yang, Magdalena Zernicka Goetz
4Dia: A tool for automated 4D microscope image alignment
Nimmy S. John, Michelle A. Urman, ChangHwan Lee
Research practice & education
Gender Imbalance in the Editorial Activities of a Researcher-led Journal
Tal Seidel Malkinson, Devin B. Terhune, Mathew Kollamkulam, Maria J. Guerreiro, Dani S. Bassett, Tamar R. Makin
Assessing Motivations and Barriers to Science Outreach within Academia: A Mixed-Methods Survey
Nicole C. Woitowich, Geoffrey C. Hunt, Lutfiyya N. Muhammed, Jeanne Garbarino
The Effect of COVID-19 on the Postdoctoral Experience: a comparison of pre-pandemic and pandemic surveys
Andréanne Morin, Britney A. Helling, Seetha Krishnan, Laurie E. Risner, Nykia D. Walker, Nancy B. Schwartz
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