Closing Date: 15 March 2021
We are interested in understanding how tissue compartmentalization and cell fate decisions take place in the Central Nervous System during embryonic development. We use the developing brain of the vertebrates – the hindbrain – as model to analyze the molecular mechanisms of tissue subdivision and cell differentiation. The project will focus in understanding how morphogenesis and cell fate acquisition are intertwined during neurogenesis. Imaging tools (3D+time imaging), and genome-editing technology will be combined using zebrafish embryos.
- Terriente, J, Pujades, C. Cell segregation in the hindbrain: do boundaries matter?. Cell Mol Life Sci, DOI: 10.1007/s00018-015-1953-8, 2015
- Zecca, A, Dyballa, S, Voltes, A, Bradley, R, Pujades, C. The order and place of neuronal differentiation establish the topography of sensory projections and the entry points within the hindbrain, J Neuroscience 35(19):7475-86, 2015
- Calzolari, S, Terriente, J, Pujades, C. Cell segregation in the vertebrate hindbrain relies on actomyosin cables located at the interhombomeric boundaries. EMBO J Apr 1;33(7):686-701, 2014
We are seeking for highly motivated and enthusiastic candidates with Graduate studies related to Biomedicine and good English communication skills. They will integrate the International PhD Program in Biomedicine of the Department of Experimental and Health Sciences (UPF), which has been awarded with the Quality Mention by ANECA (National Agency for Quality and Assessment, Spain).
The fellowship covers the stipend of the PhD student for 4 years.
The candidates will benefit from working in a dynamic group http://pujadeslab.upf.edu, at a university department which recently received the Maria de Maetzu Award for its scientific excellence https://www.upf.edu/cexs/. We are located within the PRBB in Barcelona, a vibrant scientific park harboring several research institutions.
Interested candidates are encouraged to contact Cristina Pujades. To apply, send a letter of interest, CV, and contact details of 2 referees to email@example.com