Closing Date: 15 March 2021
We are looking for a highly motivated PhD student to study development and regeneration of the thalamus in zebrafish.
Stroke is a prevalent and devastating disorder, and no treatment is currently available to restore lost neuronal function after stroke. In 10% of all stroke patients, a remote damage of the thalamus has been documented.
We utilize the genetic model organism zebrafish to explore innovative strategies for the improvement of regeneration by means of tissue engineering. The main focus is on the analysis of the development of the zebrafish thalamus and on the design, and testing of an 3D-cell culture system for reconstructing this complex brain part in-vitro. In order to optimize the strategy for tissue engineering, the project is aimed at reaching a new level of innovation which brings together (in a transdisciplinary approach) the main pillars of tissue engineering, namely 1) Developmental biology, 2) Microsurgery and Transplantation of tissues and cells, and 3) Material science. The project is set in a collaboration Dr Stefan Giselbrecht (IBG1, KIT; http://www.ibg.kit.edu/ibg1/57.php ).
The ability to quickly integrate into a team and to work within an academic research environment is essential. You must show initiative, should be well organized and must pay attention to detail. General laboratory management skills are required. You should have a very good degree in a subject related to molecular biology or cell culture. Previous experience with zebrafish would be an advantage.
The position is implemented in the Graduate School of the Biointerfaces Program of the KIT ( www.bif-igs.kit.edu ) and is available for 3 years. The project could start any time.
For further information and/or application with CV and a short statement of your current research please contact:
Dr. Steffen Scholpp