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Post-doctoral Fellow, Molecular Determinants of Glioma Initiation and Progression

Posted by , on 22 September 2020

Closing Date: 15 March 2021

Apply your developmental biology / neurobiology skills to the problem of brain cancer.

The lab of Dr. Jennifer Chan is seeking to recruit a motivated postdoctoral fellow to investigate cell fate decisions during the process of brain tumour development and progression.  Research activities in the lab focus on growth factor signalling and transcriptional regulation as determinants of neural precursor identity and fate. We use model systems that include patient-derived glioma cultures, xenografts, and engineered mouse models generated from in utero and post-natal electroporation to address our research questions.

The successful candidate will collaborate with investigators in bioinformatics to apply to apply tools of genomics, epigenomics, and transcriptomics to further define important alterations during neoplastic transformation, including interactions of tumour cells with other constituents in the microenvironment.  Early career-stage candidates (within 3 years of receiving PhD or equivalent) with experience in advanced immunohistochemistry / fluorescence microscopy; gene editing, and molecular biology; mouse modeling of disease; and/or experience in genomic approaches like RNA-seq, ChIP-seq, ATAC-seq will be preferentially considered.

The position is available immediately.

Other information

Located in Calgary, Alberta, Canada, the Chan Lab is part of the Charbonneau Cancer Institute at the University of Calgary’s Cumming School of Medicine. Within the Charbonneau Institute, we are part vibrant multidisciplinary research groups focused on childhood cancers and brain cancers. Calgary is a very ‘livable’ and family-friendly city located less than an hour’s drive from the Canadian Rocky Mountains – a haven for outdoor enthusiasts.

Application details:

Submit a brief letter of interest, your academic CV, and the names and contact information of at least three references.

Applications should be submitted as a single PDF file and sent as an email with the subject line “Post-Doctoral Fellowship, Glioma Biology” to: jawchan@ucalgary.ca

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