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Postdoctoral Position in eye development

Posted by , on 8 March 2019

Closing Date: 15 March 2021

A postdoctoral position is available to study cell signaling mechanism using eye development as a model.  Among the current projects, we are studying how extracellular signals induce cytoskeletal dynamics to control cell shape and adhesion. We are also interested in the crosstalk between FGF and other signaling pathways. The aim is to combine mechanistic studies in vitro with mouse genetics in vivo. Potential candidate should be highly motivated with a Ph.D. degree in biomedical science and a strong background in biochemistry and cell biology.  Experience in mouse genetics is desirable but not necessary.  The successful postdoc candidate will receive training in genetic, molecular and biochemical approaches in vision research, interacting with basic scientists and physicians in a multidisciplinary environment. For details of the research projects, please visit:  https://www.pathology.columbia.edu/profile/xin-zhang-phd

 

Relevant Publications

  1. Li H, Mao Y, Bouaziz M, Yu H, Qu X, Wang F, Feng GS, Shawber C, Zhang X. Lens differentiation is controlled by the balance between PDGF and FGF signaling. 2019. PLoS Biol. 17(2):e3000133.
  2. Collins TN, Mao Y, Li H, Bouaziz M, Hong A, Feng GS, Wang F, Quilliam LA, Chen L, Park T, Curran T, Zhang X. Crk proteins transduce FGF signaling to promote lens fiber cell elongation. eLife. 7:e32586.
  3. Garg A, Hannan A, Wang Q, Collins T, Teng S, Bansal M, Zhong J, Xu K, Zhang X. FGF-induced Pea3 transcription factors program the genetic landscape for cell fate determination. PLoS Genetics. 14(9):e1007660.

 

Please send CV with names and contact information of three references to: Xin Zhang, Ph.D., Departments of Ophthalmology, Pathology & Cell Biology, Columbia University, New York, NY 10032.  Email: xz2369@columbia.edu

 

The Columbia University Medical Center is located in New York City, which offers world-class museums, performing arts and numerous culture opportunities.  With top ranked Ph.D. programs, medical school and affiliated hospitals, it presents a collaborative and stimulating academic environment for research excellence.

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