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developmental and stem cell biologists

Addgene Resources to Grow Your Developmental Biology Toolkit

Posted by , on 8 November 2017

Addgene is a global, nonprofit repository that was created to help scientists share plasmids. Before we go over the developmental biology resources available at Addgene, here’s a little background on ...

The people behind the papers - David Turner & Peter Baillie-Johnson

Posted by , on 6 November 2017

Embryonic patterning is dependent on the establishment of the anteroposterior (AP) and dorsoventral axes early in development. In mammals this occurs by a breaking of symmetry in the epiblast, however ...

October in preprints

Posted by , on 2 November 2017

Our latest monthly trawl for developmental biology (and other cool) preprints. Let us know if we missed anything.   October was a monster month for preprinting (a burst of post-summer ...

The people behind the papers - Sabrina Jan, Tinke Vormer, Sjoerd Repping & Ans MM van Pelt

Posted by , on 18 October 2017

During spermatogenesis, progenitor cells must undergo tightly regulated changes to produce functional gametes. However, the genetic control of this process in humans has eluded researchers. This week we feature a ...

Adhesion and signaling by Collagen IV intercellular concentrations (CIVICs)

Posted by , on 16 October 2017

The Great Wall of Collagen IV During the long history of evolution, the key innovation that gave rise to animals with true tissues was the extracellular matrix, very conserved from ...

An interview with Jayaraj Rajagopal

Posted by , on 5 October 2017

This interview by Aidan Maartens appeared in Development, Vol 144 Issue 19   Jayaraj (Jay) Rajagopal is a Principal Investigator at the Center for Regenerative Medicine at Massachusetts General Hospital and ...

September in preprints

Posted by , on 3 October 2017

Our latest monthly trawl for developmental biology (and other cool) preprints. See last year’s introductory post for background, and let us know if we missed anything.   This month features butterfly eyespots, brain development in ...

The people behind the papers - Dan Dickinson

Posted by , on 29 September 2017

Cell polarisation is crucial for normal development and controlled by complex molecular interactions in the cytoplasm and at the membrane. Today we feature a paper recently published in Developmental Cell that describes  a single-cell biochemistry technique ...

Layered patterning systems in hair development

Posted by , on 28 September 2017

The story behind our recent paper  ‘Hierarchical patterning modes orchestrate hair follicle morphogenesis‘ , finding that distinct patterning mechanisms can co-exist during embryonic organ formation.   From the spots of ...

A new role for Insulin as a Vital Factor in Maintaining Stem Cells

Posted by , on 26 September 2017

New research conducted at the stem cell centre, DanStem, at the University of Copenhagen shows that insulin is a key determinant of embryonic stem cell potency in mammals. When large ...

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