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Displaying posts with the tag: is_archive

Dissecting modes of pattern formation using live imaging and Hidden Markov Models

Posted by , on 30 April 2020

Background/History In the early fly embryo, information encoded in a handful of maternally deposited protein gradients is fed forward through increasingly intricate layers of interacting genes, culminating in the differentiation ...

Post-doctoral position: Chromatin dynamics in early embryogenesis.

Posted by , on 5 December 2019

The Blythe Lab at Northwestern University seeks to recruit a motivated postdoctoral fellow to investigate chromatin dynamics in early Drosophila embryogenesis.   Research in the Blythe Lab focuses on a ...

A biology-modeling crosstalk to uncover feather pattern evolution

Posted by , on 20 November 2019

Richard Bailleul, Jonathan Touboul and Marie Manceau   Patterning in question: 60 years of mathematical and biological studies The coat of Vertebrates displays a stunning diversity of motifs created by ...

The serpent's maw: mouth function and the dynamics of Hydra regeneration

Posted by , on 30 September 2019

One of the biggest open questions in biology is how organisms can form complex patterns (limbs, organs, entire body plans) from initially disordered or very simple states. Every animal does ...

The people behind the papers – Heidi Connahs, Sham Tlili, Timothy Saunders and Antónia Monteiro

Posted by , on 28 May 2019

This interview, the 63rd in our series, was recently published in Development Butterfly eyespots are striking examples of animal patterning, but their developmental origins are still relatively poorly understood. A new paper in ...

Alan Turing’s patterning system can explain the arrangement of shark scales

Posted by , on 7 November 2018

Understanding how complex biological patterns arise is a long standing and fascinating area of scientific research. The patterning, or spatial arrangement, of vertebrate skin appendages (such as feathers, hair and ...

How do pigment cells wander around?

Posted by , on 29 June 2018

The story behind melanocyte BACE2, posted by Yan Zhang and Richard White. You can read our recently published full article at Developmental Cell using this link.   Our story began six ...

Lighting Up the Central Dogma in Development

Posted by , on 19 June 2018

We recently published a manuscript in Cell that describes a method to image transcription factor concentration dynamics in real time, in living embryos, using a nanobody-based protein tag that we ...

Borders and communities: solving old puzzles with new tools

Posted by , on 10 May 2018

An important question in developmental biology is how regions with distinct identity are established despite the intermingling of cells that occurs during growth and morphogenesis. Our recent work revisited some ...

The people behind the papers - David Turner & Peter Baillie-Johnson

Posted by , on 6 November 2017

Embryonic patterning is dependent on the establishment of the anteroposterior (AP) and dorsoventral axes early in development. In mammals this occurs by a breaking of symmetry in the epiblast, however ...

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