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Research Highlight #2: Blood stem cells heterogeneity arises from accessible chromatin

Posted by on May 18th, 2020

Hi there! Today’s highlight is focusing on a major question for the haematology community: what is causing blood stem cell heterogeneity? Please do not hesitate to let me know your thoughts in the comments here or on Twitter (@BioRugby)!   Highlight #2: Chromatin accessibility is the main source of heterogeneity in foetal haematopoiesis We have[…]

Marie Curie PhD fellowship / Molecular profiling of cells during regeneration: cell diversity and evolution across phyla

Posted by on December 5th, 2017

A 3-year PhD fellowship in evolutionary developmental biology and genomics is available in the lab of Michalis Averof, at the Institut de Génomique Fonctionnelle de Lyon (IGFL) in France. The fellowship is funded by the Marie Curie ITN programme EvoCELL. Some animals have the ability to regenerate parts of their body (limbs, tail, internal organs)[…]

Looking back on the adventure: exploring cell fate conversion with single cell RNA-seq

Posted by on November 21st, 2017

The story behind our recent paper: Liu Z*, Wang L*, Welch JD*, Ma H, Zhou Y, Vaseghi HR, Yu S, Wall JB, Alimohamadi S, Zheng M, Yin CY, Shen WN, Prins JF, Liu JD, Qian L (2017). Single cell transcriptomics reconstructs lineage conversion from fibroblast to cardiomyocyte. Nature, 551, 100-104 *: co-first author. https://www.nature.com/articles/nature24454  […]