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developmental and stem cell biologists
Posted by the Node Interviews, on 15 February 2017
Embryonic stem cells express genes necessary for self-renewal, and also ‘prime’ lineage-specific genes which stay silent until differentiation; the molecular players and pathways that govern the timely gene expression are still being ...Posted by the Node Interviews, on 8 February 2017
Radial glial cells are multipotent progenitors in the developing vertebrate brain. At their apical interface with the ventricular cavity around which the brain forms, they bear a primary cilium, a signalling ...Posted by the Node Interviews, on 1 February 2017
The brown alga Ectocarpus has emerged as a model system for the evolution of muticellularity. Today’s paper, from the current issue of Development, investigates the role and evolutionary history of a gene implicated ...Posted by the Node Interviews, on 25 January 2017
How does a developing embryo coordinate DNA replication with gene transcription? This fundamental question is the focus of today’s paper, recently published in eLife. We caught up with lead author Ehsan Pourkarimi ...Posted by the Node Interviews, on 4 January 2017
The tenth paper featured in this series comes from the first issue of Development for 2017, and uses computational modelling to investigate the importance of different cellular processes in spiral ...Posted by the Node Interviews, on 16 December 2016
The neural crest is a remarkable multipotent cell population that has become a model system for how epithelial cells become mesenchymal and migrate during development. In today’s post, we feature ...Posted by the Node Interviews, on 14 December 2016
Today’s paper comes from the final issue of Development for 2016, and reveals a link between bioelectricity and reactive oxygen species during tail regeneration in Xenopus. We caught up with first author ...Posted by the Node Interviews, on 30 November 2016
Today’s paper comes from the latest issue of Nature Neuroscience, and shows that in addition to chemical cues, mechanical signals are vital for axon pathfinding during brain development. We caught up ...Posted by the Node Interviews, on 29 November 2016
Today’s paper comes from the latest issue of Development, and reveals a link between phenotypic variability, cell fate switching and epigenetic silencing in zebrafish. Lead author James T. Nichols, who carried out the ...Posted by the Node Interviews, on 25 October 2016
So far in this series, we’ve featured fly nuclear pores, lizard tails, squid eyes and mouse digits, and heard from researchers working in Germany, the US and Canada. Today, we ...