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Displaying posts with the tag: is_archive

The role of WNT signalling upon injury in intestinal stem cells

Posted by , on 13 November 2024

Over the summer, I had the opportunity to conduct research in Vivian Li’s Lab, focusing on the role of WNT signalling in the response of intestinal stem cells to injury, ...

Lab meeting with the Harnoš lab

Posted by , on 12 August 2024

Meet the Harnoš lab, based in Brno, Czech Republic. The lab is interested in the role of planar polarity in neural tube formation and cell migration in Xenopus.

Patterning the butterfly wing through Wnt signaling

Posted by , on 31 August 2023

Read the story behind the paper from Tirtha Das Banerjee and Antόnia Monteiro about Wnt signaling in setting up butterfly wing patterns.

A domino effect on brain developmental evolution

Posted by , on 6 December 2019

The discipline “Evo-devo” studies the developmental basis of morphological evolution. In the field, some original animal models are emerging as interesting model organisms, enriching the knowledge in the field more ...

Of mice and chicks...

Posted by , on 1 October 2018

This is the latest dispatch from a recipient of a Development Travelling Fellowship, funded by our publisher The Company of Biologists. Learn more about the scheme, including how to apply, here, ...

Rare is Everywhere

Posted by , on 5 June 2018

The story behind FOXL1+ telocytes You can find our recently published Nature paper here   Our story began two decades ago when my mentor, Klaus H. Kaestner, identified and cloned ...

Layered patterning systems in hair development

Posted by , on 28 September 2017

The story behind our recent paper  ‘Hierarchical patterning modes orchestrate hair follicle morphogenesis‘ , finding that distinct patterning mechanisms can co-exist during embryonic organ formation.   From the spots of ...

Multiple stem cells, population asymmetry and position-dependent heterogeneity emerge as common features of a niche for Drosophila Follicle Stem Cells and mammalian Intestinal Stem Cells

Posted by , on 16 June 2017

A discussion of “Alternative direct stem cell derivatives defined by stem cell location and graded Wnt signalling,” Nat Cell Biol, 2017. 19(5): p. 433-444.   We have recently revised the model ...

Researchers grow ‘seed’ of spinal cord tissue in a dish

Posted by , on 3 September 2014

Medical Research Council (MRC) scientists have for the first time managed to turn stem cells into the specialised cells that go on to form spinal cord, muscle and bone tissue ...

Smart signaling in the developing brain

Posted by , on 10 May 2012

The WNT pathway functions in so many processes during development that it is easy to be jealous of its multi-tasking abilities.  A recent paper in Development describes the role of ...

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