The Novo Nordisk Foundation Center for Stem Cell Biology (DanStem) is looking for a postdoc to join the Serup Group

Faculty of Health and Medical Sciences
University of Copenhagen 

Institute: The Novo Nordisk Foundation Center for Stem Cell Biology – DanStem is located at the University of Copenhagen. DanStem addresses basic research questions in stem cell and developmental biology and has activities focused on the translation of promising basic research results into new strategies and targets for the development of new therapies for cancer and chronic diseases such as diabetes and liver failure. Find more information about the Center at https://danstem.ku.dk/.

Job description
The Serup group is looking for a talented postdoc with experience in stem cell biology, NGS-based methods and bioinformatics. Recently, we found that gene regulatory networks downstream of Notch signaling that regulate pancreatic cell fate decisions were highly dynamic and more complex than previously anticipated (Seymour et al., Developmental Cell 2020).  Importantly, we found that the core Notch effector, HES1 is oscillating and regulates cell fate by inhibiting entire gene regulatory networks downstream of bHLH master regulators, and this project continues our ongoing efforts to understand the molecular basis for these observations.  We identify transcription factor target genes and explore target gene regulation by ChIP-seq and mutagenesis followed by RNA-seq, using a combination of different model systems for pluripotent stem cell culture, in vitro organ/organoid culture as well as in vivo mouse models. This project will involve human ES cell differentiation, NGS-based methods and bioinformatics analysis.

We are seeking a highly motivated and ambitious candidate with experience in NGS-based methods and bioinformatics analysis with a professional profile that closely matches the qualifications below:

• The candidate is required to hold a PhD degree in stem cell/developmental biology or molecular biology.
• The candidate should have extensive experience in NGS-based methods and bioinformatics.
• Techniques such as human ES cell differentiation protocols, 3D culturing and flow cytometry is an advantage.
• A relevant publication record is essential.

Terms of employment
The fulltime employment is for 2 years with a possibility of extension and scheduled to start 1 February 2021 or upon agreement with the chosen candidate. The place of work is at DanStem, University of Copenhagen, Blegdamsvej 3B, Copenhagen.

Salary, pension and terms of employment will be in accordance with the agreement between the Ministry of Finance and AC (Danish Confederation of Professional Associations). Currently, the monthly salary starts at 34,650 DKK/ approx. 4,650 Euro (April 2020-level). Depending on qualifications, a supplement may be negotiated. The employer will pay an additional 17.1 % to your pension fund.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.

The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of 19 December 2020.

Questions
For further information, please contact Professor Palle Serup,  palle.serup@sund.ku.dk.

Foreign applicants may find this link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure
Your online application must be submitted in English by clicking ‘Apply now’ below. Furthermore your application must include the following documents/attachments – all in PDF format:

1. Motivated letter of application (max. one page).
2. CV incl. education, work/research experience, language skills and other skills relevant for the position.
3. A certified/signed copy of a) PhD certificate and b) Master of Science certificate. If the PhD is not completed, a written statement from the supervisor will do.
4. List of publications.

Application deadline:  15 November 2020, 23.59pm CET

We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements.

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are then immediately notified whether their application has been passed for assessment by an unbiased assessor. Once the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at https://employment.ku.dk/faculty/recruitment-process/.

The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities.

Interviews are expected to be held in week 49-50.

University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.