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Displaying posts with the tag: embryogenesis [Clear Filter]

YEN Conference 2017: Registration open now!

Posted by on February 8th, 2017

Young Embryologist Network 9th Annual Conference. 9th May 2017 at the Institute of Child Health, UCL, London. This year, YEN is honoured to have Dr Darren Gilmour from EMBL Heidelberg present the Sammy Lee Memorial Lecture. We are also pleased to host two invited speakers, Dr Karen Liu (King’s College London), and Professor Michael Stumpf (Imperial College London). As well as three abstract-selected talk sessions and a poster[…]

Forgotten classics- Regulating the size of the mouse embryo

Posted by on April 6th, 2016

  Snow, M. H. L., Tam, P. P. L. (1979) Is compensatory growth a complicating factor in mouse teratology? Nature 279, 555-557 Lewis, N. E., Rossant, J. (1982) Mechanism of size regulation in mouse embryo aggregates J. Embryol. exp. Morph 72, 169-181 Recommended by James Briscoe (Francis Crick Institute)     As our previous forgotten[…]

Pluripotency in the mouse and beyond…

Posted by on February 4th, 2016

Preimplantation development establishes the founding cell population of the adult mammal in the epiblast. This naïve pluripotent state employs a unique hand of transcription factors to ensure epigenetic resetting and unbiased embryonic potential. In rodents, naïve pluripotency can be captured in the form of embryonic stem (ES) cells1-4, however other mammals have proven more refractory.[…]

What do songbirds tell us about ES cells?

Posted by on January 8th, 2016

A running joke amongst avian developmental biologists is that the chicken (Gallus gallus) is the tastiest of the model organisms. A typical response from some of my mouse, frog or fish friends, would be that that is where the advantages end – the lack of the ability to do genetics in birds present limitations in[…]

Time-Lapse Recording of Pre-Implantation Mouse Development

Posted by on January 6th, 2016

This four-day long time-lapse shows the development of pre-implantation mouse embryos from the 2-cell stage to over 100-cells as the expanded blastocysts hatch from their zona pellucidas. These embryos were imaged using two-photon microscopy, which enabled us to visualize and track individual cells and lineages throughout pre-implantation development with good spatiotemporal resolution and excellent viability.[…]

Live-cell analysis of plant embryogenesis: Live-cell imaging, optical manipulation, and micro-engineering technologies

Posted by on October 16th, 2015

In multicellular animals and plants, the single-celled zygote develops into the embryo. In the model plant Arabidopsis thaliana, the zygote divides asymmetrically to form a small cytoplasmic apical cell, which is the precursor of the proembryo, and a large vacuolated basal cell, which develops into the extra-embryonic suspensor (Figure 1). Communication between the intra-embryo (proembryo[…]

From our sister journals- August 2015

Posted by on August 24th, 2015

Here is some developmental biology related content from other journals published by The Company of Biologists.         Deducing the stage of origin of Wilms tumours from a developmental series of Wt1 mutants Wilms’ tumours, paediatric kidney cancers, are the archetypal example of tumours caused through the disruption of normal development. In this[…]

From our sister journals- July 2015

Posted by on July 28th, 2015

Here is some developmental biology related content from other journals published by The Company of Biologists.         Drosophila helps to elucidate the effects of radiation therapy Children who are exposed to cranial radiation therapy (CRT) to treat brain tumours are at increased risk later in life for neurocognitive, motor and seizure disorders.[…]

An interview with Brigid Hogan

Posted by on July 11th, 2015

This interview was first published in Development.   Brigid Hogan is a developmental biologist who has worked extensively on the early stages of mouse development and is now unravelling the mysteries of lung organogenesis. She is the George Barth Geller Professor and Chair of the Department of Cell Biology at Duke University Medical Center. Brigid is[…]

From our sister journals- June 2015

Posted by on June 22nd, 2015

Here is some developmental biology related content from other journals published by The Company of Biologists.       Elucidating pulmonary hypoplasia in ciliopathies Ciliopathies are developmental disorders caused by mutations in components of the primary cilium (a microtubule-based mechanosensor organelle present in many mammalian cells), and are usually characterised by multi-organ abnormalities. Congenital lung[…]