A flipbook of zebrafish embryogenesis
Posted by Joyce Yu, on 3 January 2024
What is this?
A physical copy of Development Volume 123 Issue 1 (1996), with a flipbook at the upper corner of the issue showing zebrafish embryogenesis over 17 hours from the 2-cell stage to the 16-somite stage.
Where can this be found?
The Company of Biologists office in Cambridge, UK
Why should people care about this?
Consisting of 37 papers, this zebrafish special issue presented the results of two large screens for zebrafish mutants. The papers describe about 1500 mutations in more than 400 new genes involved in a wide range of processes that govern development and organogenesis. The mutants described in this issue provide a rich resource for many zebrafish laboratories to study embryogenesis, neuronal networks, regeneration and disease.
How would you explain this to an 8-year-old?
What happens to the first 17 hours of the life of a little zebrafish? In this science book, when you flip through the pages, you can see how the zebrafish grows from just two cells to 16 cells by the end of the book, where you can start to see the shapes of the eyes and brain of the zebrafish.
These zebrafish may look very different from us humans, but they are actually very useful for scientists to learn more about the general rules of how we grow, and what happens to us if something inside us is not working properly.
Where can people find more about it?
For more details about the making of the ‘flipbook’, read this article.
This 1996 zebrafish special issue is now fully available online.
Watch the original time-lapse recording.
Check out other ‘Show and tell’ posts and how about writing one yourself?
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