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Displaying posts with the tag: heart-development [Clear Filter]

The right information

Posted by on October 19th, 2017

Oscar H. Ocaña and M. Angela Nieto Comment on “A right-handed signalling pathway drives heart looping in vertebrates”. Nature 549, 86-90 (2017).   A fundamental aspect of vertebrates is their external bilateral symmetry, which has to some extent shaped evolutionary success. Not only is beauty associated with symmetry, enhancing an individual’s chance of mating but[…]

Ph.D. positions in Developmental Biology, Morphogenesis, Cardiovascular Biology-University of Mississippi

Posted by on October 13th, 2017

  Our research seeks to investigate the fundamental question of how cardiac cells sense and respond to their environment. Focusing on tissue interactions we seek to understand the mechanisms underlying the regulation of morphogenic and identity transformations that occur during development and disease. We use the assembly of the heart tube in zebrafish as our[…]

Two birds with one stone: CTCF control of dynamic gene expression during heart development.

Posted by on October 9th, 2017

CTCF binds to chromatin and is thought of as an architectural protein in the genome. If the genome were a text, CTCF would act like the punctuation marks, so that words are grouped together becoming meaningful sentences. When I started my PhD, the Manzanares lab had been fruitfully collaborating with that of Jose Luis Gómez-Skarmeta at[…]

Embryosafari: an attempt at illustrating development

Posted by on September 12th, 2017

Hello, Community! In July, I revealed to the world my attempts at scientific illustration. Aidan (The Node’s Community Manager) took a keen interest in my work and was very kind to share it on social media. Here is my long-promised post about my biology art (which can be viewed at www.embryosafari.com). Before I delve into[…]

Forgotten classics: Tracing the heart

Posted by on August 17th, 2016

de la Cruz, M.V., Sánchez-Gómez, C. & Palomino, M.A. (1989) The primitive cardiac regions in the straight tube heart (Stage 9–) and their anatomical expression in the mature heart: an experimental study in the chick embryo. Journal of Anatomy 165: 121-131. Recommended by Benoit Bruneau, Gladstone Institute for Cardiovascular Disease   Two previous posts in[…]

An interview with Benoit Bruneau

Posted by on November 5th, 2013

This interview first appeared in Development.   Benoit Bruneau is a developmental biologist based at the Gladstone Institutes in San Francisco. His lab studies the transcription factors and chromatin remodelling complexes that regulate cardiac organogenesis and differentiation, with the aim of uncovering the basis for congenital heart defects. Benoit has recently become an editor for Development,[…]

CNIC conference: Cardiovascular Development, Disease and Repair

Posted by on September 10th, 2013

CNIC conference: Cardiovascular Development, Disease and Repair 8-9th November 2013 Centro Nacional de Investigaciones Cardiovasculares CNIC, Madrid, Spain. Abstract submission deadline: 20th October 2013 For more information and registration please visit the following webpage: http://www.cnic-conference.com/     Cardiovascular diseases are the leading cause of death worldwide and their treatment is associated with an enormous economic[…]

A postdoctoral position is open in an INSERM laboratory (Marseille, France) Cardiac Developmental Biology

Posted by on June 24th, 2013

Our team focuses on epigenetic regulation of determination of cardiac cell lineages using stem cells and mouse embryos. The fellow will investigate how changes in the 3D chromatin configuration affect the development of the heart.  She/he will work with both wt mouse embryos (lineage tracing, micro-ChIP, 3C technologies, DNA microinjection) and from the second year[…]

Postdoc position

Posted by on January 4th, 2013

A postdoctoral position is available in the laboratory of Dr. Sophie Astrof to study roles of cell-extracellular matrix interactions in cardiovascular development and disease using mouse model system. The research will involve investigation of the role of extracellular matrix in orchestrating signaling/communication between various progenitor cell populations during morphogenesis of the aortic arch arteries.  In[…]

Embryonic development informs adult heart repair

Posted by on June 9th, 2011

After a heart attack, heart muscle is irreparably damaged, but a paper in Nature now reports that adult mouse hearts have a source of progenitor cells that can form new muscle cells after heart injury. A few years ago, studies showed that embryonic epicardial progenitor cells contribute to the cardiomyocyte lineage in developing mouse hearts.[…]