September 2018 - the Node

Research Associate – Cardiac morphogenesis and development

Posted by jbloomekatz on September 30th, 2018

The Bloomekatz laboratory in the Department of Biology at the University of Mississippi in Oxford, MS is seeking a research associate to assist in our investigations of the fundamental mechanisms underlying cardiac morphogenesis and disease using zebrafish. Please see our website thebloomekatzlaboratory.org for further details on our research. The successful candidate will have an opportunity[…]

The International Mouse Phenotyping Consortium is creating an encyclopaedia of mammalian gene function, from embryo to adult

Posted by IMPC on September 28th, 2018

The entire genome of many species has now been sequenced, but the function of the majority of genes still remains unknown. This is where the International Mouse Phenotyping Consortium (IMPC) comes in, with the goal of characterising all 20,000 or so protein-coding mouse genes. To achieve this, genes are systematically inactivated then mice are put[…]

Technician position in Molecular Biology – Lecuit Team, IBDM, Marseille, France

Posted by DelphineDauga on September 27th, 2018

A Technician position in Molecular Biology is available starting November 2018 in the group of Thomas Lecuit at the Developmental Biology Institute of Marseille (IBDM, CNRS UMR7288), Marseille, France. Funding is provided by an ERC grant. The initial appointment will be made for 1 year, with a possible extension to up to 5 years.[…]

Postdoc Position in Melbourne Australia

Posted by louiseC on September 27th, 2018

Are you interested in metabolism/nutrition/organ size control/developmental neurobiology? A postdoctoral researcher position is available in the Cheng Lab at the Peter MacCallum Cancer Institute from the beginning of 2019 in sunny Melbourne, to work on organ cross talk, metabolism, or developmental neurobiology related projects in Drosophila. We are looking for postdoc candidates with expertise in[…]

A study using Drosophila sheds light on the metastatic behaviour of human tumours

Posted by IRBBarcelona on September 26th, 2018

Most solid tumours with metastatic potential show a high degree of chromosomal instability. A study published in the journal Developmental Cell demonstrates that chromosomal instability itself promotes invasive behaviour. The researchers identify the oncogene Fos and the tumour suppressor Capicua as necessary molecular elements mediating this invasive behaviour. Barcelona, 26 September 2018.- Metastatic tumours are[…]

Postdoctoral Fellow position in Developmental Biology at Stockholm University

Posted by daiqi on September 25th, 2018

Stockholm University offers a multicultural environment in one of the world’s most dynamic capital cities. With more than 60,000 students and 5,000 staff, the University facilitates individual and societal development by providing top quality education that is tightly linked to its internationally recognized research programs. The Department of Molecular Biosciences, The Wenner-Gren Institute (MBW) unites 30[…]

An odyssey through the genesis of hematopoietic stem cells

Posted by aschmidt on September 21st, 2018

Here, Mylène Lancino and myself will introduce our motivation to investigate and delve deeper into one essential and very peculiar process of Stem Cell Biology: the de novo genesis of hematopoietic stem cells, according to a process referred to as the Endothelial-to-Hematopoietic Transition (the EHT, named initially by Kissa & Herbomel 2010). The work led to[…]

The people behind the papers – Guillaume Blin, Manuel Thery & Sally Lowell

Posted by the Node Interviews on September 21st, 2018

During early mouse development, a series of signalling interactions breaks the symmetry of the egg cylinder, spatially organising the embryo into territories that define the future axes of the body. Symmetry breaking can also be observed in embryonic stem cell (ESC) colonies cultured on micropatterned substrates, which thus provide a powerful system to test the[…]

Revisiting an old puzzle with high-resolution, three-dimensional eyes

Posted by Sha Wang on September 19th, 2018

Sha Wang, Deborah Gumucio This article shares the story behind our recent Developmental Cell paper. It tells the history of this project and how three-dimensional (3D) observations at the individual cell level transformed our preconceived ideas and brought new insights into cell dynamics in the proliferative intestinal epithelium. Epithelial tubes are present in many[…]

Nora and Nestor catch you up with the BSDB Autumn Meeting 2018

Posted by Nestor Saiz on September 19th, 2018

Hello there! This is Nora Braak and Nestor Saiz, we are based in Oxford and New York respectively and we study butterfly and mouse development. Last week we went to the BSDB Autumn meeting, which also happened to be the third workshop on Embryonic Extraembryonic Interactions. We enjoyed it so much that we wanted[…]