the community site for and by developmental biologists

Down from the crest to clear the dead

Posted by on September 30th, 2019

Yunlu Zhu & Sarah Kucenas   Introduction Cells are the building blocks of life. However, in multi-cellular organisms, millions of cells are subject to death due to injury, infection and ordinary cell turnover (Galluzzi et al., 2018). For example, epithelial cells in the small intestine rapidly renew every 2 to 6 days in most mammals,[…]

The serpent’s maw: mouth function and the dynamics of Hydra regeneration

Posted by on September 30th, 2019

One of the biggest open questions in biology is how organisms can form complex patterns (limbs, organs, entire body plans) from initially disordered or very simple states. Every animal does this at the beginning of its life, forming its full complexity from a single cell. Some are capable of similar feats even after their bodies[…]

PhD fellowship OPEN CALL to join our lab on EvoDevoGenomics in Barcelona

Posted by on September 29th, 2019

We are seeking a PhD candidate to join our EvoDevo lab in the University of Barcelona to study our favorite chordate model Oikopleura dioica, in which we are currently interested in heart development, 4D imaging of early embryo cleaving, and early developmental responses to environmental challenges. To meet our unique Oikopleura model ->  Click here[…]

Genetics Unzipped – Mergers and Acquisitions

Posted by on September 26th, 2019

We find out what happens when two cells move in together, unpack the history of genetic engineering and bleat on about Dolly the Sheep.

Tenure-track faculty Positions in Neurobiology – Molecular or Cellular Neurobiology and Neurobiology of Autism & Neurodevelopmental Disorders

Posted by on September 25th, 2019

The Department of Biological Sciences at the University of South Carolina (UofSC) invites applications for two tenure-track Assistant Professor positions in neurobiology. The successful candidates will be expected to establish an independent, extramurally funded research programs in: 1) Molecular or Cellular Neurobiology relevant to neural development and/or disease focused on cell-cell interactions; or 2) Molecular or Cellular Neurobiology[…]

Group Leader – Developmental Biology at EMBL Heidelberg, Germany

Posted by on September 25th, 2019

We are seeking to recruit an outstanding group leader who aims to explore bold new areas of biological inquiry and carry out interdisciplinary research to investigate multicellular development at all scales. How organisms respond and adapt to their environment, during development and throughout their lifetime, is of central interest. The Developmental Biology Unit seeks to[…]

Using hemimetabolous insects to investigate the origin of the tra-dsx axis

Posted by on September 24th, 2019

The story behind our recent paper in eLife.   Rapid turn over of sex determination mechanisms provides biologists with an elegant study system connecting sexual selection to molecular evolution. Striking examples of this turnover are found in African cichlids, where multiple sex determination signals exist not only within the same genera, but sometimes within the[…]

PhD project on the interaction between the enteric nervous system and colorectal cancer

Posted by on September 23rd, 2019

The research group headed by Werend Boesmans and Veerle Melotte is looking for a highly motivated and talented PhD student to investigate the role of the intrinsic innervation of the gut in cancer. The enteric nervous system, also known as the second brain, is a mostly ignored member of the tumor microenvironment but is linked[…]

Moving in concert: How lateral line primordium cells coordinate to migrate

Posted by on September 21st, 2019

Written by Tugba Colak-Champollion Story behind our recent paper in Current Biology “Cadherin-Mediated Cell Coupling Coordinates Chemokine Sensing across Collectively Migrating Cells” (Tugba Colak-Champollion, Ling Lan, Alisha R. Jadhav, Naoya Yamaguchi, Gayatri Venkiteswaran, Heta Patel, Michael Cammer, Martin Meier-Schellersheim, Holger Knaut)   Guided cell migration is a crucial event in many biological and mechanical processes.[…]

Postdoc and 0.5FTE Tech D in Exeter: NC3R waxmoth transgenesis

Posted by on September 21st, 2019

Engineering the waxmoth, Galleria mellonella, as a model for infection, immunity and inflammation – Dr James Wakefield University of Exeter  This project will generate transgenic G. mellonella lines with fluorescent haemocytes, to allow visualisation of the immune response in this non-mammalian model organism. The larvae will be injected with the human fungal pathogen Candida albicans and the haemocytes tracked via[…]