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Displaying posts in the category: Research

BSDB Gurdon Summer Studentship Report (1)

Posted by , on 27 November 2014

In 2014, the BSDB has initiated the Gurdon Summer Studentship program with the intention to provide highly motivated students with exceptional qualities and a strong interest in Developmental Biology an ...

In Development this week (Vol. 141, Issue 23)

Posted by , on 18 November 2014

Here are the highlights from the new issue of Development:   Akt acts to reprogram germ cells Primordial germ cells (PGCs) are unipotent – they go on to form germline ...

Applications of homologous recombination-mediated genome engineering

Posted by , on 17 November 2014

We recently demonstrated an improved method for homologous recombination (HR)-mediated genome editing using TALEN (Transcription activator-like effector nuclease) in zebrafish (Shin et al., 2014). In the study, we identified that ...

A TALE OF LIMBS AND GENITALS

Posted by , on 17 November 2014

The morphological evolution of limbs and external genitalia were both essential adaptions to a life on land. While the former deals with the novel locomotory challenges facing an animal invading ...

Neurogenesis in “non-neurogenic” regions

Posted by , on 13 November 2014

In the early ‘90s, the discovery of neural stem cells in the adult brain aroused hope to exploit these cells to treat neurodegenerative diseases or even induce brain regeneration. Yet, ...

A new stem cell film plus more from EuroStemCell

Posted by , on 4 November 2014

Hello! We’ve got lots of new things to share, including a film and fact sheet combo that looks at cell fate, cell identity and reprogramming, a closer look at an ...

In Development this week (Vol. 141, Issue 22)

Posted by , on 4 November 2014

Here are the highlights from the current issue of Development: Meristem maintenance is KNOX so simple Class I KNOX transcription factors, such as SHOOT MERISTEMLESS (STM) and KNAT1, are known ...

Can you beat a chicken sexer? Revisiting embryo manipulation of the avian chick.

Posted by , on 4 November 2014

Chicken, quail, zebra finch, emu, duck, crow……a simple glimpse and we immediately realize how the Aves have, as a model system left their traces in various fields of biological research. ...

Tissue-specific genome editing in Ciona embryos by CRISPR/Cas9

Posted by , on 31 October 2014

Researchers have always been interested in tissue-specific loss of function to probe the role of specific genes in embryonic development, cell physiology and disease conditions. Migration of lateral plate primordial ...

A mechanism that allows a differentiated cell to reactivate as a stem cell revealed

Posted by , on 29 October 2014

The study, performed with fruit flies, describes a gene that determines whether a specialized cell conserves the capacity to become a stem cell again. Unveiling the genetic traits that favour ...

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