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Harvard / Mass General recruiting post-doc fellow to study craniofacial developmental genetics, using human iPSC, mouse and zebrafish models.

Posted by , on 1 May 2019

Closing Date: 15 March 2021

Job Title: Post-doctoral fellow.  Position is currently recruiting.  Minimum of 2-year commitment is required.

 

Job Description

The Liao Laboratory at the Center for Regenerative Medicine at Massachusetts General Hospital in affiliation with the Division of Plastic Surgery and the Harvard Stem Cell Institute is seeking a highly motivated research fellow interested in craniofacial developmental biology and genetics.  We are currently recruiting 2 post-doctoral fellows to join our team of 10 investigators.  One post-doc position is seeking a candidate with experience in iPSC derivation and cell model work.  The second post-doc position is seeking a candidate with experience in zebrafish or mouse models.  We have a pipeline of studying human subjects with rare craniofacial conditions, where we apply human iPSC, mouse or zebrafish models to dissect the developmental genetic basis of craniofacial malformations.

 

The fellow will join a collaborative group of scientists who study the basic and translational biology of facial morphogenesis, cranial neural crest specification and development. In this instance, the fellow’s work will have a direct bearing on discovery of drugs to mitigate malformation phenotypes and functional genomics of human candidate genes implicated in orofacial clefts. We are inherently interested in the basic biology of neural crest cell specification, migration, differentiation and potential for regeneration. Integrated approaches of classical developmental and modern stem cell biology are used to explore human tissue regeneration and disease. We apply the latest technology in zebrafish genetics with routine use of CRISPR, iPSC, single cell RNAseq, Cut&Run transcriptional analysis, cell transplants, FACS, live confocal labeling and imaging, transgenics, chemical screening, and many other experimental approaches. Our laboratory has a dedicated zebrafish facility outfitted with the latest imaging, injection and cell manipulation instruments. Researchers work in open format laboratory space that foster interactions with other stellar researchers working in the Center, with ample opportunities to participate in scientific seminars and professional development.

 

The current lab members include 3 post-doc fellows, 3 graduate students, 3 technicians, 1 undergraduate and 1 high school student. The laboratory has stable funding with 4 extramural grants.  There will be ample opportunity for eligible candidate to compete for independent funding.

 

Job Requirements

The candidate should have PhD or an MD/PhD in a relevant field or equivalent training. A strong experimental foundation in iPSC derivation, iPSC analysis, cell culture, animal models are mandatory.  Additional experience with mouse genetics, development, cell, developmental, are desirable. An ancillary knowledge of genomics or systems biology is welcome. Outstanding oral and written communication skills are required.

 

Please email your inquiry, current CV, statement of interest and career goals, to Eric Liao, cliao@partners.org

 

Employing Department and Institution:Center for Regenerative Medicine, Massachusetts General Hospital.

 

 

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