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Displaying posts with the tag: human-development [Clear Filter]

The people behind the papers – George Britton and Aryeh Warmflash

Posted by on November 15th, 2019

This interview, the 71st in our series, was recently published in Development.  Our understanding of many fundamental aspects of early human development is still in its infancy, but a promising avenue for research uses advanced in vitro culturing techniques. For instance, confining human embryonic stem cells to micropatterned substrates and directing differentiation with signalling molecules has proved a powerful[…]

Two Postdoctoral Positions (Experimental & Bioinformatician) @ Babraham Institute

Posted by on October 15th, 2019

We are seeking to recruit two talented and highly motivated Postdoctoral Research Scientist to investigate the molecular regulation of lineage specification during the development of human preimplantation embryos. One position is for an experimental researcher and one position is for a bioinformatician. These new posts are part of the exciting Wellcome-funded Human Developmental Biology Initiative[…]

Development Special Issue: The Origins and Mechanisms of Developmental Disorders

Posted by on October 3rd, 2019

Development invites you to submit your latest research for our upcoming special issue: The Origins and Mechanisms of Developmental Disorders. This issue will be coordinated by two guest editors: Sally Dunwoodie and John Wallingford. Developmental disorders are among the most lethal diseases of childhood, and this recent decade has witnessed significant advances in our understanding of their genetic and environmental[…]

Harvard / Mass General recruiting post-doc fellow to study craniofacial developmental genetics, using human iPSC, mouse and zebrafish models.

Posted by on May 1st, 2019

Job Title: Post-doctoral fellow.  Position is currently recruiting.  Minimum of 2-year commitment is required.   Job Description The Liao Laboratory at the Center for Regenerative Medicine at Massachusetts General Hospital in affiliation with the Division of Plastic Surgery and the Harvard Stem Cell Institute is seeking a highly motivated research fellow interested in craniofacial developmental biology[…]

The reported birth of CRISPR-edited humans: reactions from the field

Posted by on November 29th, 2018

One scientific story has dominated the news this week: the first report of CRISPR-edited human babies being born. In an associated Node post, we’ve collected the most useful links we could find surrounding the story, and here we reached out to members of the community for their perspectives. Some responses are hopefully still coming in[…]

The reported birth of CRISPR-edited humans: useful links

Posted by on November 29th, 2018

One scientific story has dominated the news this week: the first report of CRISPR-edited human babies being born. The story’s scientific and ethical aspects stirred up heated debate, as did its means of delivery: rather than a published paper, the story broke with reports of clinical trial documents and then a YouTube video from lead[…]

Of Arms and Legs: Shedding light onto developmental gene regulation

Posted by on November 19th, 2018

Written and illustrated by: Bjørt K. Kragesteen, Malte Spielmann, and Guillaume Andrey.   In early development, the forelimb and hindlimb buds of tetrapods are morphologically uniform. However, as limb development proceeds, each individual tissue attains a characteristic morphology that ultimately defines the identity of a forelimb (arm) or a hindlimb (leg). How do undifferentiated limbs[…]

Postdoctoral Position on mammalian gastrulation

Posted by on October 3rd, 2018

Research Associate/Fellow position (3 years) to work on a BBSRC funded project investigating cell fate regulation during mammalian gastrulation in the laboratory of Dr. Ramiro Alberio (U. of Nottingham, UK), in collaboration with Prof. Jennifer Nichols (U. of Cambridge, UK) and Dr Matt Loose (U. of Nottingham). Project description: The project will investigate the molecular[…]

It’s alive! But what is it?

Posted by on July 5th, 2018

Iain Martyn & Tatiane Kanno share their experiences of the discovery of the human organizer   “It’s alive!”     Iain’s first impressions   “Hybrid human chicken embryos: HALF HUMAN – HALF CHICKEN abomination created in US lab” was my favourite headline reporting on our work1.  While the headline and accompanying article managed to miss the[…]

From stem cells to human development: Meeting reporter competition winner!

Posted by on June 29th, 2018

In May we ran a competition to find a meeting reporter for Development’s upcoming meeting on human development and stem cells. We had some wonderful entries from across the field, and are delighted today to announce the winner: Antonio Barral Gil, a PhD student in Miguel Manzanares’ Lab at CNIC (The Spanish Center for Cardiac Research) in[…]