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Displaying posts with the tag: is_archive

Shaping the embryo towards gastrulation

Posted by , on 13 May 2020

Kyprianou, C., Christodoulou, N., Hamilton, R.S. et al. Basement membrane remodelling regulates mouse embryogenesis. Nature (2020). doi.org/10.1038/s41586-020-2264-2 Morphogenesis is a complicated network of processes that involve cell shape changes, cell movements ...

Zipping up the neural tube

Posted by , on 21 April 2020

Matteo A. Molè & Andrew J. Copp Molè et al., Integrin-Mediated Focal Anchorage Drives Epithelial Zippering during Mouse Neural Tube Closure. Dev. Cell. 52, 321-334.e6 (2020). Zippering is a striking ...

Kink in the road: the notochord’s role in spine formation and scoliosis

Posted by , on 14 April 2020

By Jennifer Bagwell and Michel Bagnat   Our lab investigates the role of hydrostatic pressure as a morphogenetic force using zebrafish as a model system.  This work was originally focused ...

Preventing cellular mixing with programmed cell death

Posted by , on 12 February 2020

By Lisandro Maya-Ramos and Takashi Mikawa Bilaterality, the property of having two symmetrical sides, is widely conserved among animals. It is estimated that 99% of all animal species are bilaterians, ...

Off and On: it's more complicated than we thought.

Posted by , on 23 January 2020

We learn fairly early on when becoming biologists that both development and an organism’s response to environmental stressors require turning the right set of genes on in the right cells, ...

What might evolutionary muscle loss and pathological atrophies have in common?

Posted by , on 8 January 2020

By Mai P. Tran and Kimberly L. Cooper “It’s the cutest rodent I have ever seen, even cuter than a cuddly hamster, and it would be fun doing a rotation for ...

A domino effect on brain developmental evolution

Posted by , on 6 December 2019

The discipline “Evo-devo” studies the developmental basis of morphological evolution. In the field, some original animal models are emerging as interesting model organisms, enriching the knowledge in the field more ...

How do new cell types evolve? Sea urchins show the way….

Posted by , on 21 November 2019

We know surprisingly little about how evolution has created new cell types. One of the best examples of a recently evolved cell type comes from early sea urchin development. Most ...

A biology-modeling crosstalk to uncover feather pattern evolution

Posted by , on 20 November 2019

Richard Bailleul, Jonathan Touboul and Marie Manceau   Patterning in question: 60 years of mathematical and biological studies The coat of Vertebrates displays a stunning diversity of motifs created by ...

How do cells know their future and forget their past

Posted by , on 7 November 2019

All cells in the body contain the same genetic material. The difference between cells therefore depends solely on which genes are expressed or ‘turned on’. Now, researchers from the University ...

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