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Displaying posts with the tag: is_archive

Notch awakens: transitioning to the first differentiation step

Posted by , on 3 May 2019

The story behind our recent paper in eLife.   In the mid-1900s, Conrad Hal Waddington introduced the idea of development as a series of branching decisions taken under the control ...

Shaggy hairs and stem cells

Posted by , on 10 January 2012

Our intestinal tissue doesn’t need a New Year’s resolution to keep up its amazing productivity.  Our intestinal epithelium is replenished at breakneck speed in an assembly line that begins with ...

In Development this week (Vol. 138, Issue 17)

Posted by , on 9 August 2011

Here are the highlights from the current issue of Development: Human embryos make an early transcriptional start Human preimplantation development is a highly dynamic process that lasts about 6 days. ...

In Development this week (Vol. 138, Issue 12)

Posted by , on 24 May 2011

Here are the highlights from the current issue of Development: How transcriptional silencing goes into reverse The Polycomb group (PcG) machinery silences terminal differentiation genes in stem cell lineages. Reversal ...

In Development this week (Vol. 138, Issue 9)

Posted by , on 12 April 2011

Here are the research highlights from the current issue of Development: Cranial neural crest development: p53 faces up The tumour suppressor p53 plays multiple roles in the prevention of cancer ...

In Development this week (Vol. 138, Issue 7)

Posted by , on 8 March 2011

Here are the research highlights from the current issue of Development: A breath of fresh air: miRNAs regulate lung development Throughout development, a proper balance between the proliferation and differentiation ...

In Development this week (Vol. 138, Issue 3)

Posted by , on 4 January 2011

Here are the research highlights from the new issue of Development: Wnt/PCP signalling, microtubules and gastrulation During vertebrate gastrulation, convergence and extension (C&E) movements shape the germ layers to form ...

In Development this week (Vol. 138, Issue 1)

Posted by , on 7 December 2010

The first issue of 2011 is out now…here are the highlights: Geminin control of lineage commitment The transition between pluripotency and multi-lineage commitment during early embryogenesis must be closely regulated ...

In Development this week (Vol 137, Issue 19)

Posted by , on 7 September 2010

Here are the research highlights from the current issue of Development: Nr5a receptors reset EpiSC pluripotency Rodent embryonic stem (ES) cells that are derived from blastocysts self-renew without mitogenic growth ...

In Development this week (Volume 137, Issue 18)

Posted by , on 24 August 2010

Non-muscle myosin II translates cilia polarity In the brain, cilia on the multiciliated ependymal cells that line the brain ventricles circulate cerebrospinal fluid over the brain surface. To generate this ...

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