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Displaying posts with the tag: is_archive

How mechanical signals orchestrate stem cell fate

Posted by , on 23 August 2016

Controlling differentiation using biophysical cues from development Embryonic stem cells have the potential to become any cell type in the adult organism, but coaxing them to a specific fate continues ...

MBL Embryology Course 2016

Posted by , on 1 August 2016

“My dear, here we must run as fast as we can, just to stay in place. And if you wish to go anywhere you must run twice as fast as ...

The dynamics of chromatin when life begins

Posted by , on 20 July 2016

Fertilization marks the start of life. This is followed by highly coordinated epigenetic reprogramming that allows protamine-histone exchange, zygotic genome activation, and the generation of a totipotent embryo. However, the ...

Stem Cell & Higher-Order Chromatin Structure: Official meeting reporter wanted

Posted by , on 13 July 2016

Stem cells have the unique properties of both self renewal and differentiation into various lineages. In the last few years, chromatin architecture and noncoding RNAs are emerging as major players in both gene ...

Replicating spinal cord development with microfluidics

Posted by , on 5 July 2016

Unraveling Development Embryonic development is a complex and regulated spatiotemporal ensemble of signaling cues that control cell differentiation. Most of what we now know comes from experimenting directly on embryos. ...

New insights into sex differences in Drosophila development and physiology

Posted by , on 27 May 2016

Bruno Hudry and Elizabeth J. Rideout Male and female fruit flies differ in many aspects of development and physiology. For example, males and females differ in abdominal pigmentation, sex comb ...

Insights into the pathogenic role of UVRAG in intestinal dysplasia

Posted by , on 4 May 2016

This post highlights the approach and findings of a new research article published in Disease Models & Mechanisms: ‘Stem cell-specific endocytic degradation defects lead to intestinal dysplasia in Drosophila’. This ...

From our sister journals- March 2016

Posted by , on 18 March 2016

Here is some developmental biology related content from other journals published by The Company of Biologists.           Drosophila as a model to study human disease The latest ...

Special Issue on Organoids

Posted by , on 15 March 2016

In vitro organogenesis has exploded onto the stem cell and developmental biology scene. It is now possible to make  miniaturised approximations of many different organs – known as organoids – entirely ...

An interview with Melissa Little

Posted by , on 15 March 2016

This interview first appeared in Development.   Melissa Little is a Senior Principal Research Fellow at the Murdoch Childrens Research Institute in Melbourne, Australia. Her lab has studied kidney development ...

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