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Replicating spinal cord development with microfluidics

Posted by , on 5 July 2016

Unraveling Development Embryonic development is a complex and regulated spatiotemporal ensemble of signaling cues that control cell differentiation. Most of what we now know comes from experimenting directly on embryos. ...

New insights into sex differences in Drosophila development and physiology

Posted by , on 27 May 2016

Bruno Hudry and Elizabeth J. Rideout Male and female fruit flies differ in many aspects of development and physiology. For example, males and females differ in abdominal pigmentation, sex comb ...

Insights into the pathogenic role of UVRAG in intestinal dysplasia

Posted by , on 4 May 2016

This post highlights the approach and findings of a new research article published in Disease Models & Mechanisms: ‘Stem cell-specific endocytic degradation defects lead to intestinal dysplasia in Drosophila’. This ...

From our sister journals- March 2016

Posted by , on 18 March 2016

Here is some developmental biology related content from other journals published by The Company of Biologists.           Drosophila as a model to study human disease The latest ...

Special Issue on Organoids

Posted by , on 15 March 2016

In vitro organogenesis has exploded onto the stem cell and developmental biology scene. It is now possible to make  miniaturised approximations of many different organs – known as organoids – entirely ...

An interview with Melissa Little

Posted by , on 15 March 2016

This interview first appeared in Development.   Melissa Little is a Senior Principal Research Fellow at the Murdoch Childrens Research Institute in Melbourne, Australia. Her lab has studied kidney development ...

Editorial- Closing the circle: from organoids back to development

Posted by , on 15 March 2016

This editorial was written by Melissa Little and first appeared in Development.   Organogenesis is an inherently fascinating developmental process. It requires the creation of complex form and function from ...

What would you ask Nobel Prize Laureate Shinya Yamanaka?

Posted by , on 14 March 2016

It’s been 10 years since induced pluripotent stem cells (iPSCs) were first reported from the lab of Prof. Shinya Yamanaka. Since then, the field of direct reprogramming has grown immensely, ...

Researchers dig up new molecular details on "the other type" of stem cells

Posted by , on 11 March 2016

Scientists at IRB Barcelona and CSIC reveal that the combination of two molecular signals determines which cells that have already differentiated can regain their stem cell properties. Their studies on ...

Mouse-human neural crest chimeras: Not only a matter of black and white

Posted by , on 25 February 2016

The neural crest arises between neural and non-neural ectoderm and represents a somatic cell type with unique properties of multipotency. The neural crest cells (NCCs) migrate throughout the body and ...

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