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Continuous and Extended Ex Utero Embryogenesis in Mammals

Posted by , on 6 May 2021

Alejandro Aguilera Castrejon and Jacob Hanna on how to culture mouse embryos for longer
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Lighting Up the Central Dogma in Development

Posted by , on 19 June 2018

We recently published a manuscript in Cell that describes a method to image transcription factor concentration dynamics in real time, in living embryos, using a nanobody-based protein tag that we ...
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The people behind the papers - Dan Dickinson

Posted by , on 29 September 2017

Cell polarisation is crucial for normal development and controlled by complex molecular interactions in the cytoplasm and at the membrane. Today we feature a paper recently published in Developmental Cell that describes  a single-cell biochemistry technique ...
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Accelerated Frogs: Developmental Biology meets Particle Physics

Posted by , on 20 August 2014

I previously wrote a post about the development of a 4-D X-Ray Tomography technique for imaging early Xenopus embryos. Frog embryos are opaque due to their yolky composition and this ...
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The 1st European BioImage Analysis Symposium, Oct. 7 - 12, 2013 @ Barcelona

Posted by , on 30 August 2013

Image analysis is powerful and essential in modern biology. However, many people working on image analysis might be struggling with following problems: Which tool is appropriate to address my question? ...
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Colouring the Mouse Embryo

Posted by , on 13 August 2012

48 anatomical structures of the presented mouse embryo atlas are shown in 3D. Here is the backdrop for our recent paper in Development, “A novel 3D mouse embryo atlas based ...
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Visualizing stem cells at home

Posted by , on 13 June 2011

The Drosophila ovary is stunningly beautiful, and a playground of wonderful biological questions.  Within the germarium alone, developmental biologists can look at asymmetric division, stem cells and their niches, cell ...
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