the community site for and by developmental biologists

Book review: Updated interpretation of the principles of neural development

Posted by on December 20th, 2012

This book review originally appeared in Development. Tatsumi Hirata reviews “Neuronal Guidance: The Biology of Brain Wiring ” (Edited by Marc Tessier-Lavigne and Alex L. Kolodkin). Book info: Neuronal Guidance: The Biology of Brain Wiring. Edited by Marc Tessier-Lavigne, Alex L. Kolodkin. Cold Spring Harbor Laboratory Press (2011) 397 pages ISBN 978-0-879698-97-3 $135 (hardback) As[…]

December 20

Posted by on December 20th, 2012

Today’s recommended paper is: Growing Microtubules Push the Oocyte Nucleus to Polarize the Drosophila Dorsal-Ventral Axis Tongtong Zhao, Owen S. Graham, Alexandre Raposo and Daniel St Johnston (2012) Science 336 (6084), 999-1003 Submitted by Andrew Renault: “An example of purely basic research, using beautiful live imaging to overturn previously held ideas about how an oocyte[…]

An interview with Roger Barker

Posted by on December 19th, 2012

An interview with Roger Barker Roger Barker is Professor of Clinical Neuroscience at the Cambridge Centre for Brain Repair, and one of the authors on a recent Development paper from Elena Cattaneo’s group in Italy, about the derivation of functional neurons from human stem cells. EuroStemCell has published a range of videos by several authors[…]

December 19

Posted by on December 19th, 2012

Today’s recommended paper is: Transcription in the Absence of Histone H3.2 and H3K4 Methylation Martina Hödl and Konrad Basler (2012) Current Biology 08 November 2012 Submitted by Barry Thompson: “This paper overturns the dogma that H3K4 methylation is essential for activation of gene transcription in response to many different signaling pathways.” From December 1 to[…]

In Development this week (Vol. 140, Issue 2)

Posted by on December 18th, 2012

Here are the highlights from the current issue of Development:   Against the segmentation clock A gene expression oscillator called the segmentation clock controls the periodic formation of somites in vertebrate embryos. In zebrafish, negative autoregulation of the transcriptional repressor genes her1 and her7 is thought to control the clock’s oscillations. Delays in this negative-feedback[…]

December 18

Posted by on December 18th, 2012

Today’s recommended paper is: Cilia at the Node of mouse embryos sense fluid flow for left-right determination via Pkd2 Satoko Yoshiba et al. Science 338 (6104), 226-231 Submitted by Benoit Bruneau: “Left-right asymmetry is well studied but important mysteries have remained unsolved. This paper finally seals the deal on the importance and mechanistic role of[…]

Academic Visit to Oxford University : Thanks to Development Travelling Fellowship

Posted by on December 17th, 2012

I am a second year graduate student in Department of Chemical and Biological Engineering, Princeton University. I got a chance to visit Center for Mathematical Biology, Mathematical Institute, University of Oxford this November. I would like to thank Company of Biologist’s Traveling Fellowships program and people behind it for supporting me. It was an amazing and[…]

Travelling Fellowships

Posted by on December 17th, 2012

Do you need to learn a new technique?  Are you planning a collaborative visit?  If so please have a look at The Compnay of Biologist’s Travelling Fellowships –  The next deadline is the 31st December 2012. (No Ratings Yet) Loading…

December 17

Posted by on December 17th, 2012

Today’s recommended paper is: A system of repressor gradients spatially organizes the boundaries of Bicoid-dependent target genes. Hongtao Chen, Zhe Xu, Constance Mei, Danyang Yu and Stephen Small (2012) Cell 149 (3), 618-629 Submitted twice – by Andrew Renault and by Seema Grewal. Andrew: “How morphogens create robust and discrete responses has been a long[…]

December 16

Posted by on December 16th, 2012

Today’s recommended paper is: Specifying and Sustaining Pigmentation Patterns in Domestic and Wild Cats Christopher B. Kaelin, Xiao Xu et al. (2012) Science 337 (6101), 1536-1541 Submitted by Heather Etchevers: “I am interested in skin development and pigmentation. But this paper was justifiably published in a general science journal because to some extent, everyone has[…]