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In Development this week (Vol. 140, Issue 19)

Posted by , on 17 September 2013

Here are the highlights from the new issue of Development:   Roadmap for human trophoblast model Correct trophoblast development is essential for placenta function and embryogenesis. In humans, the early ...
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Proepicardial cells go for a swim: how fluid flows guide epicardial progenitors to the heart

Posted by , on 12 September 2013

The epicardium, the layer of cells covering the myocardium, plays an essential role in heart maturation and formation of the heart valves and coronary vasculature. It derives from the proepicardium ...
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Antibody reporting in developmental biology journals

Posted by , on 12 September 2013

We are trying to encourage scientists and journals to work together to improve reporting of antibody experiments which is often poor. See our comment article; http://f1000research.com/articles/2-153/v2 We would really appreciate ...
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The maternal squint puzzle - part 2

Posted by , on 11 September 2013

 The maternal squint puzzle – part 2 Karuna Sampath         Here is the background story for a recent paper from my lab in eLife, “An Essential Role ...
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Frogs shed new light on the midblastula transition

Posted by , on 3 September 2013

  After fertilization, embryos undergo rapid, synchronous cell divisions until the point of the midblastula transition (MBT) where the cell cycle lengthens.  This transition is also known as the maternal-zygotic ...
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E-CRISP: Design of custom gRNA constructs

Posted by , on 30 August 2013

E-CRISP is now available under: www.e-crisp.org Genome editing by applying the CRISPR/Cas system has been shown to be a promising new tool in genetics. CRISPR/Cas works by guided DNA double ...
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In Development this week (Vol. 140, Issue 18)

Posted by , on 27 August 2013

Here are the highlights from the new issue of Development:   FGF10 function in the lung branches off Lung development in mice involves specification of the primary lung field followed ...
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Recipe to make liver from stem cells...

Posted by , on 22 August 2013

  Can you imagine a supermarket where doctors could just go and pick the cells they need to cure their patients? Just like a pharmacy…or a blood bank? Well, this ...
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Bridging the gap between the sub-cellular and the tissue-organ scale

Posted by , on 22 August 2013

A major challenge when studying the cell biological bases underlying morphogenesis is represented by the gap between the sub-cellular and the tissue-organ scale (Figure 1). Ideally, one would like to ...
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X-rays and frog embryos: new features of gastrulation revealed

Posted by , on 19 August 2013

For decades, the development of the early embryo and patterning of tissues has been studied with the help of a workhorse of developmental biology, the frog embryo.  Xenopus embryos are ...
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