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Displaying posts with the tag: dna [Clear Filter]

The people behind the papers – Simon Lane and Keith Jones

Posted by on October 4th, 2017

Checkpoints ensure that mouse oocytes with DNA damage arrest in meiosis I, preventing non-viable embryo formation, however the mechanisms which activate this checkpoint have so far eluded researchers. This week we feature a paper published in the latest issue of Development that reveals that the unique ability of mouse oocytes to sense DNA damage by[…]

Of mice and men: exploring Mouse ENCODE

Posted by on December 17th, 2014

The Mouse ENCODE Project released a slew of papers late last month reporting findings from a three-year effort to comprehensively map functional elements in the mouse genome. Their major findings are summarized in an integrative paper in Nature (Yue, F. et. al., 2014). Similar to the goals of the human ENCODE project (The ENCODE Project Consortium,[…]