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Building genetic tools in Drosophila research: an interview with Gerald Rubin

Posted by on April 18th, 2016

This interview first featured on Disease Models and Mechanisms.   Gerald (Gerry) Rubin, pioneer in Drosophila genetics, is Founding Director of the HHMI-funded Janelia Research Campus. In this interview, Gerry recounts key events and collaborations that have shaped his unique approach to scientific exploration, decision-making, management and mentorship – an approach that forms the cornerstone[…]

Interview with BSDB poster winner Mathew Tata

Posted by on April 15th, 2016

Valeria Yartseva was the winner of last year’s Society for Developmental Biology (SDB) meeting poster competition. Her prize was to attend the spring meeting of the British Society for Developmental Biology (BSDB), held jointly with the British Society for Cell Biology at the University of Warwick in the UK. Continuing the interview chain, Valeria interviewed Mathew[…]

Light sheet microscopy 101: Get started with a short video protocol

Posted by on April 13th, 2016

Here you can find out more about our video protocol on using light sheet microscopy to image zebrafish eye development.   Light sheet fluorescence microscopy has quickly become a popular technique in developmental biology. This method is very gentle to the samples, with fast acquisition speed and allows capturing the samples from any angle or from[…]

The Rapstract

Posted by on September 25th, 2015

In a world first, Phil Day presents a complete summary of a peer-reviewed scientific paper in the medium of rap: The Rapstract. Original paper: Dr. Carolina Barcellos-Machado et al., Reconstruction of Phrenic Identity in Embryonic Stem Cell-Derived Motor Neurons (2014) http://dev.biologists.org/content/141/4/784.abstract Interpretation in Rap by Phil Day presented here. Subtitles available. Phil Day is the[…]

Gap junctions: versatile mediators of long-range developmental signals

Posted by on August 13th, 2015

My lab works on developmental bioelectricity, studying how cells communicate via endogenous gradients of plasma membrane resting potential (Vmem) in order to coordinate their activity during pattern regulation (Levin, 2013; Levin, 2014b; Tseng and Levin, 2013). It is well-known that resting potential is an important regulatory parameter for individual cells’ proliferation, differentiation, and oncogenic potential[…]

Adult Neurogenesis at 50: the Dresden chronicles

Posted by on July 21st, 2015

The 4th meeting in the Abcam Adult Neurogenesis conference series was held in the beautiful city of Dresden earlier this year. The conference’s aim was to put the developmental process of adult neurogenesis and its regulation into the wider context of its functional and presumed evolutionary relevance. Reporting from the meeting was our roving reporter, Nambirajan[…]

Nerves read the electrical topography of their microenvironment in making growth decisions

Posted by on June 29th, 2015

A really interesting recent paper on bioartificial limbs underscored the prospect of transplantation for problems in regenerative medicine. One key issue facing transplant technology is establishing appropriate innervation to the host. What factors control the amount of nerve emanating from an organ graft and the paths that this innervation takes? Alongside the familiar diffusible signaling[…]

Friendly hello and a bit about stress & adult hippocampal neurogenesis

Posted by on June 27th, 2015

This is my first post for the Node, so I thought I would introduce myself a little bit… I just finished my MSc in Experimental Psychology (Behavioural Neuroscience) and now I am striving towards becoming a science communicator. Although, I would like to share the research that I am interested in and was involved in,[…]

From our sister journals- June 2015

Posted by on June 22nd, 2015

Here is some developmental biology related content from other journals published by The Company of Biologists.       Elucidating pulmonary hypoplasia in ciliopathies Ciliopathies are developmental disorders caused by mutations in components of the primary cilium (a microtubule-based mechanosensor organelle present in many mammalian cells), and are usually characterised by multi-organ abnormalities. Congenital lung[…]

Cortical Microcircuit Assembly: The Migratory Path Matters

Posted by on June 10th, 2015

By Peng Kate Gao Developmental neuroscience has traditionally focused on understanding the structural assembly of the nervous system. However, recently it has increasingly been recognized that development also plays a key role in orchestrating the functional assembly of neural circuits1. The neocortex, the center of higher functions in the mammalian brain, can be characterized by its stereotypic lamination at[…]