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Displaying posts with the tag: neurogenesis [Clear Filter]

Differentiating cells mechanically limit progenitor cells’ interkinetic nuclear migration to secure apical cytogenesis

Posted by on July 17th, 2018

Press release for Yuto Watanabe, Takumi Kawaue and Takaki Miyata‘s new Development paper   Key Points Developing brains use a mechanism like the Otoshi-buta (the drop lid), a kitchen wisdom. Differentiating cells in embryonic cerebral walls form a dense filter-like layer to mechanically barrier nuclei of neural stem cells. Loss of this barrier or fence results in[…]

Adult Neurogenesis 2018: Highlights -By Zubair Ahmed Nizamudeen

Posted by on June 29th, 2018

4WH Neurogenesis: What Where Why When and How? Neurogenesis is understood as the process by which neural stem cells (NSCs) produce new neurons. In the adult mammalian brain, this process is known to persist in two restricted locations- the dentate gyrus (DG) region of the hippocampus (see figure below) and the lateral walls of the[…]

The dorsal root of the matter: Using zebrafish to study the importance of movement on early brain growth

Posted by on May 8th, 2018

In our recent paper published in eLife, we found a novel form of movement-dependent neural feedback that drives early forebrain growth in zebrafish. In this article, I discuss the problems, solutions, and lucky breaks that led to our finding. I also end up giving the mighty zebrafish larvae the credit it so deserves.   A[…]

Abcam & the Node meeting reporter competition winner: Zubair Nizamudeen

Posted by on March 20th, 2018

Earlier in the year we and Abcam ran a competition to find a meeting reporter for the upcoming Abcam Adult Neurogenesis meeting to be held in Dresden in May. Today we are delighted to announce the winner: Zubair Nizamudeen, a PhD student in Virginie Sottile’s lab at the Wolfson STEM Centre, School of Medicine, University of Nottingham, UK. Zubair’s[…]

Exploring the differences between mice and men during cerebral cortex development

Posted by on December 5th, 2017

Alzu’bi A, Lindsay SJ, Harkin LF, McIntyre J, Lisgo SN, Clowry GJ (2017) The transcription factors COUP-TFI and COUP-TFII have distinct roles in arealisation and GABAergic interneuron specification in the early human fetal telencephalon. Cerebral Cortex 27: 4677-4690.   One author’s perspective on the origins of this study (Gavin Clowry)   For me the origins[…]

PhD position in Cell Biology of Vertebrate Neurogenesis at the University of Manchester

Posted by on October 13th, 2017

Applications are invited from highly motivated and enthusiastic individuals for an MRC funded PhD position in the laboratory of Dr. Raman Das at the Faculty of Biology, Medicine and Health at the University of Manchester. This position will commence in September 2018. The successful candidate will have or expect to obtain a first or upper-second class[…]

Embryosafari: an attempt at illustrating development

Posted by on September 12th, 2017

Hello, Community! In July, I revealed to the world my attempts at scientific illustration. Aidan (The Node’s Community Manager) took a keen interest in my work and was very kind to share it on social media. Here is my long-promised post about my biology art (which can be viewed at www.embryosafari.com). Before I delve into[…]

A fine balance: tuning adult neurogenesis in the freshwater planarian

Posted by on January 12th, 2017

Comment on “Neuronal sources of hedgehog modulate neurogenesis in the adult planarian brain”, eLife 2016;5:e19735. Currie et al., eLife (2016)   Ko W. Currie, Cellular Neurobiology, Institut de recherches cliniques de Montreal (IRCM), Montreal, QC Alyssa M. Molinaro, Hospital for Sick Children, Toronto, ON Bret J. Pearson, Hospital for Sick Children, Toronto, ON   To say[…]

How to build and evolve a nervous system

Posted by on November 20th, 2016

Author Summary of “A gene regulatory network for apical organ neurogenesis and its spatial control in sea star embryos”.   Alys M. Cheatle Jarvela, Kristen A. Yankura, Veronica F. Hinman Development 2016 143: 4214-4223; doi: 10.1242/dev.134999 Very similar cell types are found across the animal tree of life. Much of animal diversity, therefore, arises not from the formation of new cells, but[…]

PhD position in Cell Biology of Neuronal Differentiation at the University of Manchester

Posted by on October 17th, 2016

  Applications are invited from highly motivated and enthusiastic individuals for a BBSRC DTP funded PhD position in the laboratory of Dr. Raman Das at the Faculty of Biology, Medicine and Health at the University of Manchester. This position will commence in September 2017.   This project builds on our recent discovery of a new form[…]