I've written a post on The Node with some of my thoughts more generally here: https://thenode.biologists.com/people-country-enough-experts/discussion/ In response to your questions: For me, this makes it almost certain I will not return to the UK. My husband is American and undertaking a medical residency in paediatrics for the next 3 years, and we both very much miss the UK and had planned, at some point, to return. I have been coming to terms with the near certainty that that now won't happen. I am also Northern Irish, and Scottish, and lived in England for all my university education. The breakup of the UK that seems inevitable and everything I am currently seeing are, frankly, heartbreaking. In terms of what can be done for science: as I've alluded to in my post, the uncertainty that exists right now is going to be terribly damaging for the UK scientifically because people have strong incentives to leave, be they EU or UK or frankly simply foreign. The UK has been a strong scientific leader and attracted great talent; I would predict that is going to be less likely to be the case. Frankly, it's hard enough getting a permanent academic position; why on earth would you make it harder going into this mess, if you could possibly avoid it. Maintaining collaborations in the face of this, and particularly as a community of developmental biologists, is key. Junior people are going to need more support than ever.

So sad that the "too many postdocs and PhDs" dates from 2010 and we're still talking about it! Happy Birthday!