the community site for and by
developmental and stem cell biologists

Behind the paper stories

Behind the paper stories

Every paper has a story behind it, and we regularly commission scientists to tell theirs. In this collection you’ll discover the highs and the lows, the chance encounters and life changing discoveries from the breadth of developmental biology and stem cell research.

Recent posts

Secret talk between epithelium and endothelium determines hair follicle stem cell fate

Posted by , on 6 November 2019

By Kefei Nina Li and Prachi Jain   Stem cells are typically defined by their ability to self-renew and differentiate. These activities are tightly controlled by both intrinsic cues and …
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“My balance comes from instability” thought Herzog (Saul Bellow, Herzog)

Posted by , on 28 October 2019

A bit of background The dependence of a protein’s function on its structure is a well-known phenomenon. Back in 1970’s, it was suggested that most proteins would fold into one …

A gnawing question: which cells are responsible for tooth renewal and regeneration?

Posted by , on 23 October 2019

By Amnon Sharir (UCSF), Allon M Klein (HMS), Ophir D Klein (UCSF) As most mouse geneticists know, treating a rodent with malocclusion of its front teeth can be a Sisyphean task: …

The serpent’s maw: mouth function and the dynamics of Hydra regeneration

Posted by , on 30 September 2019

One of the biggest open questions in biology is how organisms can form complex patterns (limbs, organs, entire body plans) from initially disordered or very simple states. Every animal does …

Using hemimetabolous insects to investigate the origin of the tra-dsx axis

Posted by , on 24 September 2019

The story behind our recent paper in eLife.   Rapid turn over of sex determination mechanisms provides biologists with an elegant study system connecting sexual selection to molecular evolution. Striking …

Moving in concert: How lateral line primordium cells coordinate to migrate

Posted by , on 21 September 2019

Written by Tugba Colak-Champollion Story behind our recent paper in Current Biology “Cadherin-Mediated Cell Coupling Coordinates Chemokine Sensing across Collectively Migrating Cells” (Tugba Colak-Champollion, Ling Lan, Alisha R. Jadhav, Naoya …

“If you notice something unusual in your experiments, don’t just throw it away!”

Read Laura Pellegrini’s piece on choroid plexus organoids 

Do you have a story to tell? We can give comments on drafts and any level of editing you want, and we particularly encourage contributions from researchers for whom English is not their first language.

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Our full archive going back to 2010 is filterable by category, tag and date.

Updated on 14 October 2021