Behind the paper stories
Every paper has a story behind it, and we regularly commission scientists to tell theirs. In this collection you’ll discover the highs and the lows, the chance encounters and life changing discoveries from the breadth of developmental biology and stem cell research.
Secret talk between epithelium and endothelium determines hair follicle stem cell fate
Posted by PrachiJain, on 6 November 2019By Kefei Nina Li and Prachi Jain Stem cells are typically defined by their ability to self-renew and differentiate. These activities are tightly controlled by both intrinsic cues and …
“My balance comes from instability” thought Herzog (Saul Bellow, Herzog)
Posted by zelhanil, on 28 October 2019A bit of background The dependence of a protein’s function on its structure is a well-known phenomenon. Back in 1970’s, it was suggested that most proteins would fold into one …
A gnawing question: which cells are responsible for tooth renewal and regeneration?
Posted by Amnon Sharir, on 23 October 2019By Amnon Sharir (UCSF), Allon M Klein (HMS), Ophir D Klein (UCSF) As most mouse geneticists know, treating a rodent with malocclusion of its front teeth can be a Sisyphean task: …
The serpent’s maw: mouth function and the dynamics of Hydra regeneration
Posted by collinslab, on 30 September 2019One of the biggest open questions in biology is how organisms can form complex patterns (limbs, organs, entire body plans) from initially disordered or very simple states. Every animal does …
Using hemimetabolous insects to investigate the origin of the tra-dsx axis
Posted by jrwexler, on 24 September 2019The story behind our recent paper in eLife. Rapid turn over of sex determination mechanisms provides biologists with an elegant study system connecting sexual selection to molecular evolution. Striking …
Moving in concert: How lateral line primordium cells coordinate to migrate
Posted by ttcolak, on 21 September 2019Written by Tugba Colak-Champollion Story behind our recent paper in Current Biology “Cadherin-Mediated Cell Coupling Coordinates Chemokine Sensing across Collectively Migrating Cells” (Tugba Colak-Champollion, Ling Lan, Alisha R. Jadhav, Naoya …
“If you notice something unusual in your experiments, don’t just throw it away!”
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Our full archive going back to 2010 is filterable by category, tag and date.