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Displaying posts in the category: Research

In Development this week (Vol. 140, Issue 2)

Posted by , on 18 December 2012

Here are the highlights from the current issue of Development:   Against the segmentation clock A gene expression oscillator called the segmentation clock controls the periodic formation of somites in ...

December 18

Posted by , on 18 December 2012

Today’s recommended paper is: Cilia at the Node of mouse embryos sense fluid flow for left-right determination via Pkd2 Satoko Yoshiba et al. Science 338 (6104), 226-231 Submitted by Benoit ...

Academic Visit to Oxford University : Thanks to Development Travelling Fellowship

Posted by , on 17 December 2012

I am a second year graduate student in Department of Chemical and Biological Engineering, Princeton University. I got a chance to visit Center for Mathematical Biology, Mathematical Institute, University of ...

December 17

Posted by , on 17 December 2012

Today’s recommended paper is: A system of repressor gradients spatially organizes the boundaries of Bicoid-dependent target genes. Hongtao Chen, Zhe Xu, Constance Mei, Danyang Yu and Stephen Small (2012) Cell ...

December 16

Posted by , on 16 December 2012

Today’s recommended paper is: Specifying and Sustaining Pigmentation Patterns in Domestic and Wild Cats Christopher B. Kaelin, Xiao Xu et al. (2012) Science 337 (6101), 1536-1541 Submitted by Heather Etchevers: ...

Counting transcripts to track cell state

Posted by , on 16 December 2012

Many years ago, we started to use micro-arrays to look at how gene expression changes during differentiation of lateral mesoderm. In particular we were interested in differentiation leading to the ...

December 15

Posted by , on 15 December 2012

Today’s recommended paper is: Self-Organized Shuttling: Generating Sharp Dorsoventral Polarity in the Early Drosophila Embryo Michal Haskel-Ittah et al. (2012) Cell 150 (5), 1016 – 1028 Submitted by Tohru Yano: ...

December 14

Posted by , on 14 December 2012

Today’s recommended paper is: Whole-genome microRNA screening identifies let-7 and mir-18 as regulators of germ layer formation during early embryogenesis Alexandre R. Colas, Wesley L. McKeithan, Thomas J. Cunningham, et ...

December 13

Posted by , on 13 December 2012

Today’s recommended paper is: Offspring from Oocytes Derived from in Vitro Primordial Germ Cell-like Cells in Mice Katsuhiko Hayashi et al. (2012) Science 338 (6109), 971-975 Submitted by Eva Amsen: ...

Don't get rid of the middleman

Posted by , on 12 December 2012

There are a lot of situations in life where the “middleman” is unnecessary and costly.  In cells, that middleman is necessary and fascinating at the same time.  The sequence of ...

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