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Displaying posts in the category: Research

When real life becomes equations: Control of Epiblast and Primitive Endoderm specification during mouse preimplantation development.

Posted by , on 23 September 2014

During mouse preimplantation development, the zygote divides and forms three distinct lineages: one embryonic called the Epiblast (Epi) and two extraembryonic called trophectoderm (TE) and Primitive Endoderm (PrE). The first ...

In Development this week (Vol. 141, Issue 19)

Posted by , on 23 September 2014

Here are the highlights from the current issue of Development:   Modelling fate decisions in the early mouse embryo In the early embryo, the first fate decision separates the trophectoderm ...

The origin of blood

Posted by , on 4 September 2014

As for the origin of species, the question of the origin of blood during development has unleashed a lot of passion among the scientific community. As a matter of fact, ...

Designing ChIP primers

Posted by , on 4 September 2014

Hello everyone, Recently I got assigned with the task of designing good primers for ChIP. My supervisor advised me to use the Primer BLAST tool from NCBI together with AmplifiX ...

Researchers grow ‘seed’ of spinal cord tissue in a dish

Posted by , on 3 September 2014

Medical Research Council (MRC) scientists have for the first time managed to turn stem cells into the specialised cells that go on to form spinal cord, muscle and bone tissue ...

In Development this week (Vol. 141, Issue 18)

Posted by , on 2 September 2014

Here are the highlights from the current issue of Development:   Mcc: a new player in gastrulation The mutated in molorectal cancer (Mcc) gene has been described as a tumour ...

Yoshiki Sasai: stem cell Sensei

Posted by , on 21 August 2014

This obituary first appeared in Development.   Stefano Piccolo looks back at the life and research of his friend and colleague Yoshiki Sasai.   On 5 August 2014, Yoshiki Sasai died at ...

Accelerated Frogs: Developmental Biology meets Particle Physics

Posted by , on 20 August 2014

I previously wrote a post about the development of a 4-D X-Ray Tomography technique for imaging early Xenopus embryos. Frog embryos are opaque due to their yolky composition and this ...

In Development this week (Vol. 141, Issue 17)

Posted by , on 19 August 2014

Here are the highlights from the current issue of Development:   HSCs make a Runx1 for it The emergence of haematopoietic stem cells (HSCs) during early mammalian development is crucial ...

In Development this week (Vol. 141, Issue 16)

Posted by , on 6 August 2014

Here are the highlights from the current issue of Development:   PCP signalling is dispensable for neural crest migration The neural crest (NC) is a transient and migratory population of ...

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