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Displaying posts in the category: Research

The maternal squint puzzle - part 2

Posted by , on 11 September 2013

 The maternal squint puzzle – part 2 Karuna Sampath         Here is the background story for a recent paper from my lab in eLife, “An Essential Role ...

Frogs shed new light on the midblastula transition

Posted by , on 3 September 2013

  After fertilization, embryos undergo rapid, synchronous cell divisions until the point of the midblastula transition (MBT) where the cell cycle lengthens.  This transition is also known as the maternal-zygotic ...

E-CRISP: Design of custom gRNA constructs

Posted by , on 30 August 2013

E-CRISP is now available under: www.e-crisp.org Genome editing by applying the CRISPR/Cas system has been shown to be a promising new tool in genetics. CRISPR/Cas works by guided DNA double ...

In Development this week (Vol. 140, Issue 18)

Posted by , on 27 August 2013

Here are the highlights from the new issue of Development:   FGF10 function in the lung branches off Lung development in mice involves specification of the primary lung field followed ...

Recipe to make liver from stem cells...

Posted by , on 22 August 2013

  Can you imagine a supermarket where doctors could just go and pick the cells they need to cure their patients? Just like a pharmacy…or a blood bank? Well, this ...

Bridging the gap between the sub-cellular and the tissue-organ scale

Posted by , on 22 August 2013

A major challenge when studying the cell biological bases underlying morphogenesis is represented by the gap between the sub-cellular and the tissue-organ scale (Figure 1). Ideally, one would like to ...

X-rays and frog embryos: new features of gastrulation revealed

Posted by , on 19 August 2013

For decades, the development of the early embryo and patterning of tissues has been studied with the help of a workhorse of developmental biology, the frog embryo.  Xenopus embryos are ...

In Development this week (Vol. 140, Issue 17)

Posted by , on 13 August 2013

Here are the highlights from the current issue of Development: GDNF’s got a nerve Innervation of the mammalian pancreas is crucial for endocrine and exocrine function. Neural crest cells that ...

Remembrance of Brains Past

Posted by , on 30 July 2013

What would happen to your memories and personality if, after decades of adult life, some portion of your brain was replaced with the progeny of fresh stem cells (as might ...

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