A postdoctoral position is available in the lab of Helen McNeill at Washington University School of Medicine in St. Louis, Missouri, USA (mcneilllab.wustl.edu). Our laboratory studies how tissue organization and tissue patterning are coordinated in development, using flies, mice and hydra. A major focus of the lab is understanding how Fat cadherins and the Hippo pathway regulate tissue development (Blair & McNeill, Current Opinions in Cell Biology, 2018; Yeung et al., eLife 2017; McNeill & Reginensi, JASN 2017; Reginensi et al., Nat Commun 2016; Reginensi et al., Development 2015; Badouel et al., Development 2015; Bagherie-Lachidan et al., Development 2015; Sing et al, Cell 2014).
We are looking for a highly motivated postdoctoral fellow to join a multidisciplinary research team investigating fundamental problems in development and cell biology. Projects are available in: (1) Using imaging to explore how the Hippo pathway and mechanical feedback impact branching morphogenesis in the mouse kidney (2) Exploring how mutations in Fat4 affect branching and nephron progenitor renewal in mouse models. 3) Using Drosophila as a model to dissect biochemically and genetically Fat signaling in vivo. Assays used include live imaging, RNA-seq, ChIP-seq, mass spectrometry, biochemical approaches and mouse and fly CRISPR mutagenesis.
Applicants should have a PhD and demonstrated relevant research experience. Excellent communication skills and the ability to work in collaboration are essential. A strong background in molecular biology, developmental biology, or cell biology is preferred. Experience in imaging signal transduction, biochemistry and bioinformatics is a plus.
Consistently ranked among the top 10 US medical schools, Washington University School of Medicine offers a highly interactive and stimulating academic environment for scientists in training. The lab is in a highly collaborative environment within the Department of Developmental Biology and Center of Regenerative Medicine. We are located in the heart of the Central West End, a vibrant St. Louis neighborhood adjacent to major cultural institutions and one of the country’s largest urban parks. We offer competitive salary and benefit packages and candidates are eligible to apply for a Rita Levi-Montalcini Postdoctoral Fellowship offered by the Center of Regenerative Medicine.
To apply for this position please submit a CV, a cover letter describing research interests, and contact information for two references who can comment on your research to mcneillh@wustl.edu. Applications will be reviewed promptly until the position is filled. Washington University is an equal opportunity employer and complies with applicable EEO and affirmative action regulations.
Summer of 2018 will genuinely be the summer to remember for all 24 MBL embryology students.
To me, the MBL embryology 2018 course was like a wonderland full of breath-taking experimental adventures, unexpected discoveries, scientific growth and madly passionate researchers. Thus, let me take you on a journey across the five wonders of this course.
1. Woods Hole and the MBL campus.
Woods Hole is a very unique place under our sun. Even though it is tiny and you could see it all in about half an hour, do not be tricked! It has so much to offer! Let’s start with the ocean and all the beaches, including secret beaches (I cannot talk more about this… but if you find yourself there, look for them – you will not be disappointed!)! Stony beach belongs to the MBL campus and is five minutes away from the labs and dormitories. During the day, it always served as a place to slow down, to remind us of how lucky we were to be there and take a very refreshing swimming break between lunch and the afternoon labs. On July nights it had yet another surprise prepared for us – bioluminescence. Swimming surrounded by the bioluminescent unicellular dinoflagellates and embryology course friends under the starry sky felt so magical that sometimes I still wonder if that was just a creation of my tired mind.
Another stunning place, abundant with marine animals, is Eel Pond. Its very photogenic beauty greeted me every morning while walking to get some last-minute coffee and breakfast in Swope building, before our first morning lecture. On the other side of the pond, you can find the Marine Resources Center (MRC), where we got to see a vast variety of marine animals, such as octopuses, skates, sea urchins and many others. After grabbing breakfast, on our way to the Speck auditorium, we passed the Lillie building. This is another special place, and definitely worth visiting. First of all, MBL hosts fantastic Friday evening lectures in the unique Lillie auditorium (recorded lectures can be accessed here: http://videocenter.mbl.edu/videos/). It also has a great library, where we got a chance to hold T. H. Morgan’s Nobel Medal and rare books starting from ‘The Origin of Species’ signed by Charles Darwin himself, to the ‘Opticks: or A Treatise of the Reflexions, Refractions, Inflexions and Colours of Light’ by Isaac Newton and published in 1704.
I want to finish this quick overview of the MBL campus with the Loeb Laboratory Building. This was a building where real wonders happened. This was the place where we spent days and nights familiarising with, studying, observing, grafting, injecting, imaging embryos – from tunicates to nematodes to mammalians… And this brings me to the second wonder of the course.
The after-course cheer together with Shinuo Weng and neural crest field colleagues – Weiyi “Lily” Tang and Andrea Attardi.
2. All the species.
The embryology course lasted six weeks. In the first week, we laid our hands on tunicates – Ciona embryos, and beautiful echinoderms – sea urchin and sea star embryos. We experienced the power of the simple Ciona embryo electroporation method in order to label cells of interest or even acquire transgenic animals. Echinoderm injections were slightly more challenging but were very rewarding once we could observe bright fluorescence under the microscopes. The second week was dedicated to the study of the regenerative capacities of hydra, flatworm planaria and its related species the Hofstenia worm. The things we did to them were mind-boggling… We cut them in half, we chopped them in pieces, and grafted them into each other using a sophisticated method scientifically known as ‘Shish kebab’ technique. We were surprised to see that the animals went on as if nothing had happened, giving us a very much needed relief – we kept them happy and alive. The week continued with indestructible tardigrades and predictable C. elegans worms. On the third and fourth weeks, we jumped onto vertebrate model organisms – chick, mouse, frog and zebrafish embryos. We had the opportunity to perform classical embryology experiments, such as zone of polarising activity (ZPA) grafts into the anterior limb mesenchyme to generate a mirror-image duplication of a developing limb in chick or induce the secondary axis in frog embryos. In week five we continued with developmental biology classics – we got introduced to the icon of developmental genetics that yielded six Nobel prizes in Physiology and Medicine and been awarded to a total of ten scientists, one of whom I had an honour of meeting and having a dinner with during the course – Eric F. Wieschaus. The most important things that I learnt from him about success were – work really hard, never stop being curious, explore in the lab and don’t be afraid of becoming an expert in failing.
In addition to the fruit fly, we got to play with a plethora of different arthropods, such as butterflies and parhyale. This was a transformative week in terms of microscopy imaging skills for all the embryology students. With the wonderful help and valuable tips and tricks of Nipam Patel and a PhD student from D. Sherwood’s lab – Dan Keeley, we finally felt as if we befriended and mastered all the complex and powerful microscopes we had around us. In our final week, we explored the wonders of the ctenophore, cephalopod, gastropod and annelid embryos using our last reserves of energy. It was a great experience to study these non-conventional animal models and try completely new experiments that were never done before with the help of faculty and teaching assistants!
Drosophila embryo stained for even-skipped, fushi tarazzu and DAPI.
3. Knowledge and skills
Every morning we had fantastic lectures by faculty coming from different developmental biology areas. Altogether we covered the most important concepts of development, starting from cytoplasmic determinants and inductive signals required for cellular commitment, to metazoan body plan establishment, all the way to organ morphogenesis and regeneration. Additionally, we looked into evolutionary concepts and questions, new emerging technologies and discussed more philosophical questions, such as the importance of transparent and open science.
Before joining this course, I had a very limited set of embryo manipulations skills. I was mainly used to ‘smash’ zebrafish embryos for the –omics analysis. However, for my future career, I am planning to stay in the developmental biology field and perform more functional embryo experiments. Unmistakably, this course was revolutionary for my developmental biology knowledge and embryo handling skills! At the very start of the embryology course, we had a most important workshop on tool making and handling of marine embryos, led by the tool making virtuoso Jon Henry. At the start, the whole process sounded slightly ‘bonkers’ to me. For example, would you ever consider pulling your eyelashes out and glue them to a glass needle for embryo manipulations? No? Neither had I before this workshop… Nonetheless, we had to make a mouth pipette using rubber tubes, cut our hairs, pull out our eyelashes and eyebrows for gentle embryo handling and dissection tools, very often accompanied by the extensive use of fire to pull and polish pipettes, and tungsten dissection needles… However, soon I understood the power of being creative and do what you can with what you have! Indeed, without all these tools, none of the daring experiments would have been possible. We were also so fortunate to learn from embryo manipulation experts and legends, such as Dave McClay and Ray Keller.
Now that all the embryology students are back to their own benches, I am pretty sure every single one of us is re-making all the tools we learnt and very likely inventing new ones for our own research. (Maybe sometimes while hiding from health and safety officers at night or appearing nuts to our colleagues’ eyes…)
4. Transformative scientific experience
The MBL embryology course is the place where I almost entirely lost the fear of scientific failure. First of all, our course directors, David Sherwood and Richard Schneider, from day one re-assured us that this was not a competitive environment and that we all should be ourselves at all times! This was a great start! Second, we did not have to take any exams or report our progress to anyone! We only presented our work, including failures, in an amusing (a lot of flying balls were involved) and very relaxed manner every two weeks. Importantly, we had a wide range of reagents in our fridges and freezers, top-notch microscopes, experts of the developmental biology field helping us and NO fear! This was the greatest part of the course! To explore, play, try, free our minds from dogmas. And I failed. I failed so badly, so many times. In the beginning, it still gave me somewhat gloomy feelings about not being capable of mastering a technique in a completely new organism in one day (!!!), but after a week or two, these feelings were gone. I was no longer afraid of going for more complicated experiments even though very often I had to embrace the failure. But don’t get me wrong! It is not that from now on I am ready to keep on failing and stay positive about it. No! However, from now on I will no longer be afraid of trying something new, challenging, creative! And I am sure I will fail many more times, but this will not discourage me from pursuing complicated experiments, primarily because in real life I will have more than one or two days to succeed! To sum up, I really share the feeling of one of our great course faculty member, Alejandro Sánchez Alvarado, who, after taking this course himself, knew that he “no longer needed to ask for a permission to do science”.
5. Friendships for life
The cherry on the top of the Embryology 2018 cake was the friendships that formed between the students. Before starting this adventure, most of us were utter strangers to one another. However, on our very first day, we were captivated by each other’s research questions, methodology, talents, and personalities. We were so diverse, and so we had a brilliant opportunity to learn not only from the faculty and teaching assistants but also from each other. The chemistry and dynamics of our group were extraordinary. Every single individual was so hard working, motivated, talented and remarkably friendly and eager to help. We have been through everything together – the lows of failed experiments, the highs of the ones that actually worked, exhaustion, laughter, late nights on the beach, countless hours of conversations in the break room, sharing dorm rooms and so much more that we will never forget. On the 8th of July, our genuine connection symbolically materialised into our victory against the Physiology Course students, during the traditional softball game between the two courses. Overall, I feel very privileged to have attended this prestigious course together with these beautiful people, who are very likely to shape the future of developmental biology field. Spoiler alert – the future of developmental biology is in perfect hands!
Admiring the sunset with my friends Bruno Moretti, Aastha Garde, Sandra Edwards and Andrew Fraser at the Knob, Falmouth, MA.
Lastly, I would like to thank the course directors, all faculty members, course and teaching assistants. You were so great! I would also like to thank all the financial aid contributors that made my attendance possible – Burroughs Wellcome Fund, The Company of Biologists Ltd, Horace W. Stunkard Scholarship Fund, CoB/BSDB Travel Award and the MRC Weatherall Institute of Molecular Medicine Student Travel Fund. Altogether, being part of such a vibrant and brilliant community of developmental biologists made me fall in love with this field once again and reinforced my enthusiasm to continue cracking the remaining mysteries of embryo development!
There is grandeur in this view of life, with its several powers, having been originally breathed a few forms or into one; and that, whilst this planet has gone cycling on according to the fixed law of gravity, from so simple a beginning endless forms most beautiful and most wonderful have been, and are being, evolved.
– Charles Darwin
I spent the summer of 2018 at the Marine Biological Laboratory (MBL) in Woods Hole, Massachusetts, US as a student in the Embryology Course. Here, I will reflect on what was a very transformative experience, and while doing so, I would like to share my insights on the beauty and wonder of diversity in developmental biology.
Prior to coming to Woods Hole, my understanding of developmental biology was limited. I studied biochemistry as an undergrad in the Philippines and trained as a chemist. I was not formally exposed to developmental biology research until recently, when I started my PhD in Alexander Aulehla’s Lab at the European Molecular Biology Laboratory (EMBL) in 2016. The desire to broaden my knowledge of underlying principles, mechanisms, and processes in animal development prompted me to attend the Embryology Course this year.
During the Embryology Course, I was introduced to at least a hundred different animal species, spanning both classical and emerging models of development. I worked on organisms beyond what I imagined. I got the chance to learn about and do experiments on several animals like sea squirts and sea urchins, ctenophores and tardigrades, shrimps and snails, and annelids and flatworms. I was fascinated by how the left-right asymmetry of sea squirt embryos significantly relies on its rotation during embryogenesis, and mesmerized by the symmetry and patterning of the skeleton of the pluteus larva of sea urchins. I was enthused by the coordinated beating of cilia on ctenophores, and excited by the unique cleavage pattern of tardigrade embryos. I was astonished by the differences in segmentation in the dorsal and ventral axes of Triops, a freshwater shrimp, and captivated by the establishment of chirality of the shells of snails. I was thrilled by how Pectinaria, a marine annelid, builds its home from grains of sand, and amazed by the regenerative capacity of flatworms like planaria.
ON THE BEAUTY AND WONDER OF DIVERSE EMBRYOS
An illustration of some of the organisms we worked on during the course, arranged to spell EMBRYOLOGY.
We used this for our banner during the July 4th Parade and also printed it on our batch T-shirt.
Illustration by: Ashley Rasys
Integral to studying embryogenesis and animal diversity, the Embryology Course highlighted the strength of comparative embryology in furthering our grasp of unifying principles in development. For instance, the establishment of diverse body plans was a recurring theme throughout the course. It is fascinating how the same toolkit, a set of genes known as Hox genes, lay down the blueprint in patterning the body of very different animals like cephalopods (e.g., octopus) and insects. While all start as single cells, different embryos develop to form very different organisms. The endless beauty and wonder of animals around us, like tardigrades on lichens, ctenophores in sea water, and butterflies on flowers, is intriguing and inspiring. It is even more intriguing and inspiring how some of the developmental concepts and mechanisms could apply not only to animals, but also plants and microorganisms.
In addition to the diversity in organisms that were available to study embryonic development, I had the privilege to interact and do science with a very diverse group of people, coming from different research backgrounds. I learned a lot about regeneration from Jack Allen and Anneke Kakebeen who work on regeneration in planaria and frogs, respectively. Aastha Garde and Sandra Edwards provided insights on cell migration, cell invasion, and epithelial-to-mesenchymal transition. This jived very well with Jayson Smith’s expertise on the cell cycle. On another hand, Katherine Nesbit emphasized the interplay between development of embryos and their environment. Meanwhile, Stefania Gutierrez gave fresh perspectives on animal development with her expertise in colonial tunicates. In parallel, Laurel Yohe and Melvin Bonilla offered a distinct evolutionary point-of-view on acquisition of traits. Andrew Fraser and Shinuo Weng, our mechanical engineers, uniquely saw embryogenesis in terms of forces and mechanics, and Bruno Moretti, our physicist, lended his expertise in optics for functional imaging of developmental processes. Anna Yoney was the go-to person on germ layer patterning, while Darcy Mishkind was the in-house expert on left-right asymmetry. We also had people in the batch who worked on development of reptiles, with Ashley Rasys studying eye development in lizards and Boris Tezak investigating sex determination in turtles. Maximilien Courgeon was most keen on studying the development of the brain and the nervous system. Martyna Lukoseviciute and Marla Tharp were the specialists on gene regulation and chromatin dynamics, while Weiyi (Lily) Tang and Andrea Attardi were the experts on gene regulatory networks. Catherine May was particularly interested in the evolution of cell types, and Shiri Kult was most curious about bone and cartilage development.
While we all worked on the same group of organisms during the course, equipped with our expertise, we tackled the development of these animals at different vantage points. We became more aware of our skill sets, which complemented each other. Being in a diverse group allowed us to challenge dogma, encouraged us to be comfortable with our ignorance, and let us acknowledge the gaps in our knowledge. This created an environment where we embraced naivety, which proved to be conducive in being bold and asking fearless questions. We found ourselves doing classical experiments that were performed by Hilde Mangold and Hans Spemann on frog embryos, Thomas Hunt Morgan on planaria, and Ethel Browne on hydra. We explored the promise of modern approaches in developmental biology research, like advanced and quantitative imaging, 3D printing, and CRISPR-Cas. We took on risky projects, embraced failure (which happened quite often), and celebrated success (when it happened very seldomly). Together with the faculty and the TAs, we relied on each other to supplement our understanding of embryology. Together, we learned beautiful and wonderful things.
ON THE BEAUTY AND WONDER OF DIVERSE RESEARCH BACKGROUNDS
Outdoor Sweat Box (question and answer session) with Susan Strome.
Photo credit: David Sherwood
The enthusiasm, joy, and excitement transcended gender identity and sexual orientation, nationality, and cultural background. This camaraderie went beyond the lab, evident in our Sunday out-of-the-lab trips and spontaneous dance parties, our convergent extension-inspired presentation during the July 4th parade (please see B. Duygu Özpolat’s video here), and our victory during this year’s softball game with the Physiology course. The diversity catalyzed the building of a strong network of scientists and lifelong friends.
The Embryology course also showcased exemplary initiatives to promote inclusive and equitable access to developmental biology research. The microscopes we used, for example, were kindly sponsored by different companies like Zeiss, Nikon, Bruker, and Mizar. During a visit, Manu Prakash, together with Team Foldscope (check out their website here), distributed cheap paper microscopes and highlighted the importance of frugal science. Alexis Camacho-Avila, a very brilliant undergrad from an underrepresented minority group, attended the first two weeks of the course through the Society of Developmental Biology (SDB) Choose Development! Fellowship Program. Moreover, there were generous scholarship grants and fellowships available to cover the expenses of attending the course. Personally, I am grateful for the financial support from the Burroughs Wellcome Fund, the Helmsley Charitable Trust, the Horace W. Stunkard Scholarship Fund, and The Company of Biologists. These initiatives, among others, ensure barriers to diversity in developmental biology research are overcome. Witnessing and experiencing this was empowering.
ON THE BEAUTY AND WONDER OF DIVERSE DEVELOPMENTAL BIOLOGISTS
Embryology Course 2018 class photo, taken at the Waterfront Park in Woods Hole.
Photo credit: Bruno Moretti
Like the embryos we study, the community of developmental biologists has evolved to take endless forms. We are biologists, chemists, and physicists. We dance, ride a skateboard, and win softball games. We are parents, sons, and daughters. We come from different parts of the world, speak different languages, and grow from different cultural backgrounds. While being different, we share the passion to push developmental biology research forward.
Before ending, I would like to use this platform to thank various people who made the Embryology Course special. I thank my classmates whom I shared this truly transformative experience. I thank Christopher Pineda, Amber Rock, and Hannah Rosenblatt, our Course Assistants, who made sure the course ran smoothly. Also, I express many thanks to all the faculty and teaching assistants (TAs), who shared their knowledge and wisdom. I am further thankful to Richard Schneider and David Sherwood, our Course Directors, for granting me this life-changing opportunity. Lastly, I am grateful to my family, my lab, and every one who supported me and encouraged me to apply. I am very grateful to be part of #embryo2018 (a Twitter-friendly collective term referring to Embryology Course 2018 and every one who took part in it).
It has been around a month since I left Woods Hole. While I recollect on everything that happened during the Embryology Course and reflect on how it has a significant impact on what I do now and in the future, the weather here in Heidelberg has become cooler and the leaves on trees have started to turn into different shades of red. This summer is ending most beautifully and most wonderfully.
Applications are invited for a Postdoctoral Research Associate to study clonal dynamics and the regulatory mechanisms controlling branching morphogenesis in the developing mouse lung. In a multidisciplinary collaboration, this experimental project will be supervised jointly by Dr Emma Rawlins (Gurdon Institute; http://www.gurdon.cam.ac.uk/research/rawlins), in whose lab the work will be based, and Prof. Ben Simons (Gurdon Institute and Department of Applied Mathematics and Theoretical Physics, https://www.gurdon.cam.ac.uk/research/simons). Between the labs, recent research activities have targeted the molecular mechanisms of cell fate decision-making during lung development and the cellular basis of branching morphogenesis in lung and other ductal tissue types(Nikolic et al., Elife, 2017; Scheele et al., Nature, 2017, Hannezo et al., Cell, 2017). We now aim to recruit an outstanding experimental Postdoctoral Research Associate, who is interested indeveloping quantitative experimental approaches tostudy cellular decision-making in the developing mouse lung, with an emphasis on lineage tracing assays.
Applicants should have a PhD in a relevant subject, or be close to completion of their degree. Expertise in general areas of developmental/stem cell biology including lineage tracing and/or live-cell imaging, image analysis and cell signalling mechanisms would be suitable for this position. Experience of in vivomouse experiments would be an advantage.
The successful applicant will learn state-of-the-art clonal analysis mechanisms and the application of quantitative models to biological questions. They will have a strong publication record and an excellent aptitude for research and career development. We are looking for applicants who are collaborative with effective communication skills and enjoy working in a team. Proven capacity to design, execute, and interpret your own experiments is essential.
Limited funding: The funds for this post are available for 2 years in the first instance.
To apply online for this vacancy, please use the University’s Web Recruitment System, where you will need to register an account (if you do not have an account already) and log in before completing the online application form. See http://www.jobs.cam.ac.uk/job/18053/ for more details.
Applications should include a CV and a brief statement outlining key areas of expertise and reasons why you would like to join the project. Informal enquiries can be addressed to Dr Emma Rawlins (e.rawlins@gurdon.cam.ac.uk). Please quote reference PR16060 on your application and in any correspondence about this vacancy.
The University values diversity and is committed to equality of opportunity. The University has a responsibility to ensure that all employees are eligible to live and work in the UK. Benefits include generous maternity/paternity leave, flexible working and funds for returning carers and other family-friendly schemes.
A postdoctoral position is available in the laboratory of Dr. Sophie Astrof at Thomas Jefferson University to study roles of cell-extracellular matrix (ECM) interactions in cardiovascular development and congenital heart disease. We have recently discovered that progenitors within the second heart field (SHF) give rise to endothelial cells composing pharyngeal arch arteries (Dev Biol 421:102–111, 2017). Projects in the lab focus on the role of ECM in regulating the development of SHF-derived progenitors into endothelial cells and their morphogenesis into blood vessels. The successful candidate will combine genetic manipulation, embryology, cell biology, and confocal imaging to study molecular mechanisms by which cell-ECM interactions and tissue microenvironment regulate cardiovascular development. Additional projects focus on the investigation of cell type-specific and cell-autonomous functions of fibronectin in development and signaling (Development 143:88-100, 2016)
Astrof laboratory is a part of a modern and well-equipped Center for Translational Medicine at Jefferson Medical College (http://www.jefferson.edu/university/research/researcher/researcher-faculty/astrof-laboratory.html) located in the heart of Philadelphia. To apply, please send a letter of interest detailing your expertise, CV and names and contact information of three references to sophie.astrof@gmail.com
Postdoc Position in Bioinformatic Analysis of
Neural Development in Nematostella
There is a vacancy for a 2 year Postdoc position at the Sars International Centre for Marine Molecular Biology (www.sars.no/) in the research group headed by Dr. Fabian Rentzsch. The position is funded on a TOPPFORSK grant from the Norwegian Research Council, and is available from October 2018. The Sars Centre belongs to the University of Bergen, and is partner of the European Molecular Biology Laboratory (EMBL) www.embl.de/. The place of work will be at the Sars Centre.
About the project/work tasks:
The Rentzsch group studies neurogenesis in the cnidarian Nematostella vectensis with the aim to understand cellular, molecular and evolutionary aspects of nervous system development (see Richards and Rentzsch, Development, 2014 and 2015). The project employs computational analyses of differential gene expression and ATAC seq data to characterize the transcriptional changes that control the development of neural progenitor cells into differentiated neurons. The successful candidate will have the opportunity to further develop the project in line with his/her interests. If desired, contribution to the experimental validation of the computational analyses is possible.
Qualifications and personal qualities:
The applicant must hold a Norwegian PhD or an equivalent degree within informatics or molecular biology or must have submitted his/her doctoral thesis for assessment prior to the application deadline. It is a condition of employment that the PhD has been awarded.
Experience in differential gene expression analysis of high-throughput sequencing data, proficiency in a programming language and/or shell scripting is desired.
Interest in gene regulatory networks, developmental biology or stem cell biology is an advantage.
Ability to work both independently and in close collaboration with others in a structured manner.
Personal communication skills to interact with the scientific environment are required.
Proficiency in both written and oral English
We can offer:
A good and professionally challenging working environment
Salary at pay grade 57 upon appointment (code 1352), currently NOK 490.900 gross p.a. Further promotions are made according to length of service in the position
Enrolment in the Norwegian Public Service Pension Fund
A position in an inclusive workplace (IA enterprise)
Good welfare benefits
Applications in English must include:
A cover letter that includes brief account of the applicant’s research interests and motivation for applying for the position
CV
List of publications
The names and contact information for two reference persons. One of these must be the main advisor for the PhD programme.
Transcripts and diplomas and official confirmation that the doctoral thesis has been submitted
Relevant certificates/references
Please send your application with attachments electronically via JobbNorge by clicking on the button “Apply for this job” (choose English page) – see here. If your diploma, grade transcripts and other documentation are in a language other than English, you must upload certified translations of these (diploma and grade transcripts in a Scandinavian language are acceptable). Please note that applications will be assessed only with the information available in JobbNorge when the deadline expires. It is the applicant’s responsibility to ensure that all relevant attachments are submitted by the deadline.
Applications by e-mail only will not be considered.
Closing date for application: September 16th, 2018
General information:
Further information about the position can be obtained from Group Leader Dr. Fabian Rentzsch, tlf +47 55 58 43 04, email fabian.rentzsch@uib.no.
The Department of Genetics at Yale University School of Medicine invites applications for junior or senior tenure-track faculty positions. The search is open to investigators from all areas of biological and biomedical research. We are particularly interested in applicants working in one of the following areas Developmental Biology, Imaging, Quantitative Biology, Computational Biology, Genomics, Systems Biology, and Genetics. Applications from investigators working at the interface of these areas will be strongly considered. The rank of the appointment will be commensurate with experience and the positions come with a substantial start-up package.
The Department of Genetics comprises an exceptional group of 31 primary basic science faculty with research interests including fundamental aspects of Developmental Biology, Genetics, Genomics and Epigenetics, using different model systems including flies, worms, fish and mouse, and humans (https://medicine.yale.edu/genetics/). The Department is closely associated with science initiatives at Yale including The Cancer Center, The Center for Neuroscience, The Stem Cell Center and the Yale Center for Genome Analysis
Candidate must hold a Ph.D., M.D., or equivalent degree. Applicants should upload a cover letter, a curriculum vitae, a description of previous research (1 page), a concise statement of research plans (up to 2 pages), reprints of 2 publications, and the names of 3 references to the Interfolio website at: https://apply.interfolio.com/52614). Specific inquiries about the position may be sent to the attention of Dr. Antonio Giraldez, Chair of the Department of Genetics, at genetics.admin@yale.edu. Applications will begin to be evaluated on November 1, 2018.
Interviews will take place as part of a multidisciplinary symposium including candidates for different searches. Please reserve the dates of January 15, January 22 and February 11 (snow date) as potential dates for the symposium in case you are selected for an interview.
Yale University is an Affirmative Action/Equal Opportunity employer. Yale values diversity among its students, staff, and faculty and strongly welcomes applications from women, persons with disabilities, protected veterans, and underrepresented minorities.
The Wellcome Trust – Medical Research Council Cambridge Stem Cell Institute is an international centre of excellence for stem cell research and regenerative medicine. Scientists in the Institute collaborate to advance our knowledge of various stem cell types and to perform pioneering work in translational research areas, providing the foundation for new medical treatments (https://www.stemcells.cam.ac.uk/).
Applications are invited for an MRC-funded Research Assistant position to join the research team of Dr. Brian Hendrich (https://www.stemcells.cam.ac.uk/research/pis/hendrich). The successful applicant will integrate with a team working to understand how chromatin remodelling proteins control gene expression during cell fate decisions in pluripotent cells.
The ideal candidate will have considerable laboratory experience in biochemistry (western blots, immunoprecipitations), molecular biology (real time PCR, RT-PCR, transfections, gene cloning), and mammalian cell culture, and be familiar with the principles of good laboratory practice. Communication and note-keeping skills are essential, as is the ability to work independently as well as within a laboratory team, as required. You may be required to give oral presentations of your research work to other lab members and prepare written reports for your supervisor.
You must be able to follow procedures and methodologies. You should be able to organise, perform and analyse experiments with minimal instruction and supervision. The post will require frequent weekend work and a flexible approach to working hours. Careful observation and accurate record keeping are essential.
You should have been awarded a Bachelor’s degree or equivalent.
Fixed-term: The funds for this post are available until 31 December 2020 in the first instance.
To apply online for this vacancy and to view further information about the role, please visit: http://www.jobs.cam.ac.uk/job/18507/. This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the ‘Apply online’ button and register an account with the University’s Web Recruitment System (if you have not already) and log in before completing the online application form.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
The closing date is Tuesday, 11 September 2018, with interviews expected to take place the week commencing 24 September 2018.
Please quote reference PS16474 on your application and in any correspondence about this vacancy.
The University values diversity and is committed to equality of opportunity.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
The Duke Regeneration Next Initiative (RNI) is partnering with the Duke Department of Pharmacology and Cancer Biology (PCB) to hire a tenure-track faculty member at the rank of Assistant Professor. We invite applications from accomplished candidates with expertise in developmental and cell biology, stem cell biology, mechanisms of tissue regeneration, quantitative biology, imaging, signaling, chemical biology, or related areas. Candidates must have a PhD, MD, or equivalent degree. Women and underrepresented minority candidates are especially encouraged to apply. Applicants should submit a curriculum vitae, a 3-page total summary of accomplishments and research plans, and at least 3 letters of recommendation by November 1, 2018 to: https://academicjobsonline.org/ajo/jobs/11605
The new Center for Stem Cell & Organoid Medicine (CuSTOM) at Cincinnati Children’s Hospital Medical Center (CCHMC) is launching a major new initiative to recruit outstanding tenure-track or tenured faculty at the Assistant to Associate Professor level.
CuSTOM (www.cincinnatichildrens.org/custom) is a multi-disciplinary center of excellence integrating developmental and stem cell biologists, clinicians, bioengineers and entrepreneurs with the common goal of accelerating discovery and facilitating bench-to-bedside translation of organoid technology and regenerative medicine. Faculty in CuSTOM benefit from the unique environment and resources here to accelerate their studies of human development, disease and regenerative medicine using pluripotent stem cell and organoid platforms.
CCHMC is a leader in organoid biology and one of the top ranked pediatric research centers in the world, providing a unique environment for basic and translational research. Among pediatric institutions CCHMC is the third-highest ranking recipient of research grants from the National Institutes of Health. CCHMC continues to make major investments in research supporting discovery with 1.4 million square feet of research space and subsidized state-of-the-art core facilities including a human pluripotent stem cell facility, CRISPR genome editing, high-throughput DNA analysis, biomedical informatics, a Nikon Center of Excellence imaging core and much more.
We invite applications from innovative and collaborative investigators focused on basic or translational research in human development and/or disease using stem cells or organoid models. A focus on neurobiology, pulmonary, vascular or cardiac biology would synergize with existing institutional strength. Successful candidates must hold the PhD, MD, or MD/PhD degrees, and will have a vibrant research program with an outstanding publication record.
Applicants should submit their curriculum vitae, two to three page research statement focused on future plans, and contact information for three people who will provide letters of recommendation to CuSTOM@cchmc.org. Applications must be submitted by November 16th, 2018.
The Cincinnati Children’s Hospital Medical Center, and the University of Cincinnati are Affirmative Action/Equal Opportunity Employers. Qualified women and minority candidates are especially encouraged to apply.
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