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The rabbit blastocyst modelling (for) vertebrate gastrulation

Posted by , on 5 January 2015

Form and function of animal gastrulation have been longstanding classics accompanying the rise of experimental embryology, and – as if to square the circle in the literal sense – the ...
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Of mice and men: exploring Mouse ENCODE

Posted by , on 17 December 2014

The Mouse ENCODE Project released a slew of papers late last month reporting findings from a three-year effort to comprehensively map functional elements in the mouse genome. Their major findings ...
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In Development this week (Vol. 142, Issue 1)

Posted by , on 16 December 2014

Here are the highlights from the current issue of Development:   Planar cell polarity squeezes in on the action The planar cell polarity (PCP) pathway regulates the polarization of epithelial ...
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Seeing cells from a different angle

Posted by , on 7 December 2014

Thanks to microscopy, scientists can compete with the most talented photographers and take the most astonishing pictures! Although I have been focusing on microscopy pictures in this blog, microscopy is ...
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BSDB Gurdon Summer Studentship Report (2)

Posted by , on 27 November 2014

In 2014, the BSDB has initiated the Gurdon Summer Studentship program with the intention to provide highly motivated students with exceptional qualities and a strong interest in Developmental Biology an ...
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BSDB Gurdon Summer Studentship Report (1)

Posted by , on 27 November 2014

In 2014, the BSDB has initiated the Gurdon Summer Studentship program with the intention to provide highly motivated students with exceptional qualities and a strong interest in Developmental Biology an ...
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In Development this week (Vol. 141, Issue 23)

Posted by , on 18 November 2014

Here are the highlights from the new issue of Development:   Akt acts to reprogram germ cells Primordial germ cells (PGCs) are unipotent – they go on to form germline ...
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Applications of homologous recombination-mediated genome engineering

Posted by , on 17 November 2014

We recently demonstrated an improved method for homologous recombination (HR)-mediated genome editing using TALEN (Transcription activator-like effector nuclease) in zebrafish (Shin et al., 2014). In the study, we identified that ...
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A TALE OF LIMBS AND GENITALS

Posted by , on 17 November 2014

The morphological evolution of limbs and external genitalia were both essential adaptions to a life on land. While the former deals with the novel locomotory challenges facing an animal invading ...
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Neurogenesis in “non-neurogenic” regions

Posted by , on 13 November 2014

In the early ‘90s, the discovery of neural stem cells in the adult brain aroused hope to exploit these cells to treat neurodegenerative diseases or even induce brain regeneration. Yet, ...
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