Applications are invited for a Research Assistant/Associate within the Division of Infection & Immunity at UCL in Dr Gillian Tomlinson’s laboratory.
We are seeking highly motivated individuals interested in integrating cutting-edge human and zebrafish models to study the immunopathogenesis of tuberculosis. The post is funded by a Medical Research Council Clinician Scientist Fellowship entitled “Tuning the immune response in tuberculosis”, and combines a human experimental tuberculosis challenge model with studies using Mycobacterium marinum infection of zebrafish to identify and validate host factors that calibrate a favourable immune response in tuberculosis.
The post-holder will be supervised by Dr Gillian Tomlinson based in the Cruciform Building at UCL. Dr Tomlinson works with Dr Mahdad Noursadeghi’s and Professor Benny Chain’s group’s which study host immune responses to infectious diseases at genome wide level with a particular focus on tuberculosis (www.innate2adaptive.com). The zebrafish work will be supported by the fully managed world class research aquarium at UCL.
The post is available for 3 years in the first instance, subject to satisfactory probationary and annual appraisals. There is an established track record for department post-doctoral staff gaining personal fellowships. Independently minded and talented investigators will be encouraged and supported in seeking such fellowship support.
Key Requirements
Applicants must have an MSc (or equivalent degree) and/or a PhD (or equivalent degree) or about to be awarded in a relevant subject.
Candidates must have experience of working with zebrafish including microinjection and in vivo imaging.
Evidence of significant scientific contribution including publications and presentations at conferences is also essential.
Appointment at Grade 7 is dependent on having been awarded a PhD. If this is not the case, initial appointment will be at research assistant Grade 6B (salary £29,485 – £31,091 per annum) with payment at Grade 7 being backdated to the date of final submission of the PhD thesis.
To apply for this post please follow this link to the UCL website: https://atsv7.wcn.co.uk/search_engine/jobs.cgi?owner=5041178&ownertype=fair&jcode=1580418
The Department of Biology invites applications for a tenure-track position at the assistant professor level, beginning Fall 2017. Applicants should have a Ph.D.; post-doctoral experience is desirable. The strongest candidates will demonstrate a commitment to teaching and an active research program that can involve motivated undergraduates from diverse backgrounds. We seek a broadly trained systems biologist whose research and course offerings complement those of other faculty in the department. We invite applicants who use contemporary methodologies, including computational and/or modeling techniques, to study biological systems at the cellular or organismal level. Teaching responsibilities include participation in a team-taught introductory course, a one-semester intermediate level course in systems biology with a laboratory, and an advanced seminar with research projects in the area of the applicant’s interest. Participation in the interdisciplinary Neuroscience program is possible. The College offers competitive start-up packages to support faculty research and teaching, as well as a generous sabbatical policy (http://www.swarthmore.edu/provosts-office/sabbatical-support).
Located in the immediate suburbs of Philadelphia and just 20 miles from Wilmington DE, Swarthmore College is a highly selective liberal arts college whose mission combines academic rigor with social responsibility. Swarthmore has a strong institutional commitment to diversity, and actively seeks and welcomes applications from candidates with exceptional qualifications, particularly those with demonstrable commitments to a more inclusive society and world. Applicants from traditionally underrepresented groups are strongly encouraged to apply. For more information on Faculty Diversity and Excellence at Swarthmore, see http://www.swarthmore.edu/faculty-diversity-excellence/information- candidates-new-faculty.
All application materials should be submitted on Academic Jobs Online [https://academicjobsonline.org/ajo/jobs/7479] by October 8, 2016. Questions regarding this position should be addressed to the Search Chair at biosearch@swarthmore.edu.
Monash University is seeking an outstanding candidate to manage and lead the Department of Anatomy and Developmental Biology within the Faculty of Medicine Nursing and Health Sciences. The Department of Anatomy and Developmental Biology is one of six departments of the School of Biomedical Sciences and a leader within its discipline. Areas of research expertise include renal and lung biology, epithelial and reproductive biology, inflammation, embryology, cancer, stem cell biology and regenerative medicine.
The successful candidate will capitalise and build on existing educational and research strengths to create a high-performing team of academics and professional staff who not only provide outstanding educational opportunities to the students in the school but also, through membership of the Monash Biomedicine Discovery Institute, contribute to the research strategy and output of the institute.
To be successful in this role you will have a proven track record of individual research excellence and evidence of leadership through building and developing capability in an academic or research environment.
The Varshney lab is recruiting a highly motivated, passionate and independent individual with excellent interpersonal skills to play a key role in advancing the mission of the lab.
We are focused on tackling the huge challenge of systematically validating the flood of human candidate disease genes identified in various genome- wide association (GWAS) and whole-exome sequencing studies by developing disease models in zebrafish.
The successful applicant will use zebrafish and the emerging genomic technologies to understand the disease pathology of human non-syndromic hearing loss. Our research interests span multiple disciplines: genetics, genomics, molecular biology, and developmental biology.
A recent doctorate in Biological Sciences or related field with experience in Molecular Biology, Cell & Developmental Biology, and Genetics is required. Experience with zebrafish is desirable, but not essential.
Please send a curriculum vitae and summary of research interests to:
Gaurav Varshney, Ph.D.,
Assistant Member,
Functional & Chemical Genomics Program,
Oklahoma Medical Research Foundation.
Email: Gaurav-Varshney AT omrf.org
The Oklahoma Medical Research Foundation (OMRF) is an independent, not-for-profit, biomedical research institute adjacent to the campus of the University of Oklahoma Health Sciences Center (OUHSC) in Oklahoma City. OMRF investigators enjoy close scientific interactions with OUHSC faculty and participate in OUHSC graduate programs. OMRF has been selected as one of the best research institutions for post-docs from 2011 to 2013 in the USA by The Scientist journal. Additional information about OMRF can be found at the Oklahoma Medical Research Foundation web site: http://omrf.org
Department/Location: Wellcome Trust – Medical Research Council Cambridge Stem Cell Institute, University of Cambridge
Salary: £28,982-£37,768
Reference: PS10005
Closing date: 04 October 2016
Post-doctoral fellow: healthy ageing of human haematopoietic stem cells.
Fixed-term: The funds for this post are available until 31 October 2019 in the first instance.
The Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute is an international centre of excellence for stem cell research and regenerative medicine. Scientists in the Institute collaborate to advance our knowledge of various stem cell types and to perform pioneering work in translational research areas, providing the foundation for new medical treatments. The Institute currently comprises 29 research groups based across 6 sites in Cambridge. In 2018 all researchers will move to a new building on the Cambridge Biomedical Campus.
Applications are invited for a research associate to join Dr Laurenti’s group. We combine state-of-the-art experimental and computational methods to study the unique biological and molecular properties of human Haematopoietic Stem Cells (HSCs).
The post holder will join a new multidisciplinary project funded by the BBSRC. This collaboration between Dr Laurenti and Prof. Göttgens laboratories has as principal aim the investigation of the functional and molecular heterogeneity of HSCs throughout a human lifetime, with a particular focus on the effects of healthy ageing. The project will combine single cell, transcriptomics, epigenomics, flow cytometry, single cell functional assays in vitro and in vivo.
The successful candidate is expected to creatively and independently carry out their own research project, while collaborating on a regular basis with a team of experimentalists and computational biologists. They will also effectively communicate their work in writing and oral presentations at internal meetings and international conferences.
Candidates should hold a PhD in a relevant field. In particular, they will have a strong background either in stem cell biology, haematology, immunology or ageing. Extensive experience with flow cytometry, mouse models and tissue culture is required. The candidate should also possess molecular biology skills. Additional expertise with high-throughput sequencing data and the R programming language would be desirable. Finally, they will have demonstrated scientific achievement with an excellent publication record.
The start date is flexible but can be as early as November 2016.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a security check.
To apply online for this vacancy and to view further information about the role, please visit: http://www.jobs.cam.ac.uk/job/11327. This will take you to the role on the University’s Job Opportunities pages. There you will need to click on the ‘Apply online’ button and register an account with the University’s Web Recruitment System (if you have not already) and log in before completing the online application form.
The closing date for all applications is the Tuesday 04 October 2016.
Here we highlight some developmental biology related content from other journals published by The Company of Biologists.
Meritxell Huch, Wellcome Trust Sir Henry Dale Fellow at the Gurdon Institute in Cambridge, was interviewed as a Cell Scientist to Watch(she’s certainly one for developmental biologists to watch too!).
Kang-Yell Choi and colleagues found that retinoic acid stabilisation of HRas is required for neuronal differentiation during brain development
The Gönczy lab identified Aurora-A kinases as crucial regulators of spindle positioning from worms to humans.
Paul Lasko and colleagues identified the centrosomal protein Bsg25 as a crucial regulator of mitosis and embryonic development.
Pamela Yao and colleagues investigateda pool of Sonic Hedgehog contained in extracellular vesicles around neurons.
Takashi Yamamoto and colleagues presenteda super-ovulation method paired with genome engineering in mice.
Judith West-Mays and colleagues showed that loss of the transcription factor AP-2β in neural crest cells leads to multiple eye defects, providing a model for early-onset glaucoma
Using patient-derived stem cells, Mylène Hervé and El Chérif Ibrahim implicated miRNAs and the splicing factor NOVA-1 in familial dysautonomia
Kathryn Knight reportedfrom ‘Improving Experimental Approaches in Animal Biology: Implementing the 3Rs’, a conference held in June that showcased the various ways researchers can change their habits to ensure the ethical use of animals in research.
Glen Watson and colleagues found that repair of adult murine hair cells – which is normally only minimal – is enhanced by sea anemone repair proteins.
Adriana Briscoe and colleagues identifiedan expanded number of photoreceptor classes and sexual dimorphism in their expression in a species of nymphalid butterflies
We are seeking a postdoctoral fellow interested in studying social behavior using zebrafish models at the Novartis Institutes for Biomedical Research (NIBR), Cambridge, USA. The goal of the study is to identify genetic and neural basis of social behavior in zebrafish.
Education and preferred qualifications: Ph.D. (completed or near completion) in behavioral neuroscience or related fields; experience in quantitative, large-scale analysis of behavior is a plus; prior experience in zebrafish is not required.
Interested candidates may send their CV, and contact address of three potential referees to ajeet.singh[at]novartis.com. For general information regarding postdoctoral fellowships at the NIBR, please look at http://postdoc.nibr.com/.
Our latest monthly trawl for developmental biology (and other cool) preprints. See June’s post for background, and let us know if we missed anything
It was another bumper month for preprints, as bioRxiv’s Richard Sever celebrated:
This month we found three pieces on the development of the spinal cord, three investigations into gene expression networks in the early fly embryo, some in vivo cell biology featuring centrosomes and kinesins, as well as a lot of evolutionary content and some very cool sounding tools, perhaps the most striking of which is a hand-powered centrifuge modelled on a whirligig! bioRxivprovided the bulk of the preprints, with one coming from PeerJ.
Assembly of Radically Recoded E. coli Genome Segments. Julie E. Norville, Cameron L. Gardner, Eduardo Aponte, Conor K. Camplisson, Alexandra Gonzales, David K. Barclay, Katerina A. Turner, Victoria Longe, Maria Mincheva, Jun Teramoto, Kento Tominaga, Ryota Sugimoto, James E. DiCarlo, Marc Guell, Eriona Hysolli, John Aach, Christopher J. Gregg, Barry L. Wanner, George M. Church
Highly parallel direct RNA sequencing on an array of nanopores. Daniel R Garalde, Elizabeth A Snell, Daniel Jachimowicz, Andrew J Heron, Mark Bruce, Joseph Lloyd, Anthony Warland, Nadia Pantic, Tigist Admassu, Jonah Ciccone, Sabrina Serra, Jemma Keenan, Samuel Martin, Luke McNeill, Jayne Wallace, Lakmal Jayasinghe, Chris Wright, Javier Blasco, Botond Sipos, Stephen Young, Sissel Juul, James Clarke, Daniel J Turner
August was meant to be a quiet month, with researchers (in Europe, at least) leaving the lab for a well earned break and winding down before the start of the academic year…but here on the Node we’ve had another bumper month full of diverse content. Happy reading!
Meetings
We had a wonderful report from Joaquín Navajas Acedo, Aleisha Symon and Tsai-Ming Lu from the Woods Hole Embryology Course. They really managed to capture the intense excitement and slight mania of the course, and I’m sure made a lot of readers eager to sign up for next year. I reported from the BSD-ISD in Boston: a fantastic conference, and a wonderful city. I also got to meet Yusuff and Mathew who carried on the SDB-BSDB interview chain (long may it continue!).
We started a new series to complement our usual research posts: The People Behind the Papers, highlighting the faces behind recent exciting developmental biology papers. We started with an interdisciplinary team from Heidelberg who uncovered how nuclear pore complexes get into the nuclear envelope, and then featuredThomas Lozito, author of a recent Development paper on lizard tail regeneration.
Applications are invited for a tenure track Assistant Professor faculty position in the Division of Developmental Biology (DB) at Cincinnati Children’s Hospital Medical Center (CCHMC).
DB is home to a large community of developmental biologists (please visit our web site at: http://www.cincinnatichildrens.org/research/divisions/d/dev-biology/default/). We are a highly collaborative interdisciplinary group of basic scientists and clinicians studying fundamental questions in developmental biology, the genetic basis of pediatric disease and regenerative medicine. Being embedded in CCHMC, one of the top ranking pediatric research centers in the world, creates a unique environment in which clinical translation of basic science is greatly enhanced. CCHMC is making a major long-term investment in basic and translational research and developmental biology is one of the pillars in this effort.
DB faculty have access to state of the art subsidized cores, to high-quality graduate and MD/PhD programs, and to training programs for postdoctoral fellows, clinical fellows, residents and clinical faculty. Successful candidates must hold the PhD, MD, or MD/PhD degrees, have recently completed postdoctoral training, have published significant original work and have a mature research plan.
Applicants should submit their curriculum vitae, two to three page research statement focused on future plans, and contact information for three people who will provide letters of recommendation to DB_devbiologists@cchmc.org. Applications must be submitted by December 2, 2016.
The Cincinnati Children’s Hospital Medical Center, and the University of Cincinnati are Affirmative Action/Equal Opportunity Employers. Qualified women and minority candidates are especially encouraged to apply.
The Tanentzapf lab 
