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PhD Studenship in soma-germline communication and signaling regulation in the Drosophila testis (Medway School of Pharmacy, Universities of Kent and Greenwich)

Posted by on February 13th, 2020

A PhD position is available in the lab of Fani Papagiannouli (@Medway School of Pharmacy, Universities of Kent and Greenwich) to study soma-germline communication and the role of cortical polarity in signaling regulation during Drosophila spermatogenesis. The position is funded by a Medway School of Pharmacy Post Graduate Research Scholarship.  Stem cells are critical for[…]

BSDB Gurdon/The Company of Biologists 2019 Summer Studentship Report – Jake Cornwall Scoones

Posted by on January 29th, 2020

Established by the British Society for Developmental Biology in 2014, The Gurdon/The Company of Biologists Summer Studentship scheme provides financial support to allow highly motivated undergraduate students an opportunity to engage in practical research during their summer vacation. Each year, ten successful applicants spend eight weeks in the research laboratories of their choices, and the feedback[…]

Off and On: it’s more complicated than we thought.

Posted by on January 23rd, 2020

We learn fairly early on when becoming biologists that both development and an organism’s response to environmental stressors require turning the right set of genes on in the right cells, at the right time. Clearly, for “on” to be meaningful, other genes have to be “off,” and many disordered conditions are associated with misexpression of[…]

BSDB Gurdon/The Company of Biologists 2019 Summer Studentship Report – Lauren Mulcahy

Posted by on January 18th, 2020

Established by the British Society for Developmental Biology in 2014, The Gurdon/The Company of Biologists Summer Studentship scheme provides financial support to allow highly motivated undergraduate students an opportunity to engage in practical research during their summer vacation. Each year, ten successful applicants spend eight weeks in the research laboratories of their choices, and the feedback[…]

Post-doctoral position: Chromatin dynamics in early embryogenesis.

Posted by on December 5th, 2019

The Blythe Lab at Northwestern University seeks to recruit a motivated postdoctoral fellow to investigate chromatin dynamics in early Drosophila embryogenesis.   Research in the Blythe Lab focuses on a critical period of embryogenesis termed the maternal-to-zygotic transition (MZT). During this time, embryos establish an initial ‘ground state’ of chromatin structure that defines the initial[…]

PhD DTP opportunity: Cell Biology, Univ. Manchester

Posted by on November 11th, 2019

Definition of integrin signalling networks underlying neuron growth in vivo   Application deadline: 31 January 2020 Application info: LINK Project enquiries: Andreas.Prokop@manchester.ac.uk Martin.Humphries@manchester.ac.uk   Cell adhesion molecules (CAMs) of the plasma membrane physically tie cells together into tissues, both via interaction of cells with other cells or with ECM (extracellular matrix); they also constitute hubs[…]

Using hemimetabolous insects to investigate the origin of the tra-dsx axis

Posted by on September 24th, 2019

The story behind our recent paper in eLife.   Rapid turn over of sex determination mechanisms provides biologists with an elegant study system connecting sexual selection to molecular evolution. Striking examples of this turnover are found in African cichlids, where multiple sex determination signals exist not only within the same genera, but sometimes within the[…]

POSTDOC IN DEVELOPMENTAL METABOLISM (Francis Crick Institute, London)

Posted by on July 12th, 2019

Roles of metabolism in the developmental origins of health and longevity A postdoctoral research position funded by the Wellcome Trust is available in the laboratory of Dr. Alex Gould at the Francis Crick Institute in London. The lab works on the mechanisms by which dietary nutrients during development can have profound long-term effects upon adult[…]

Collaboration: All the things we cannot see (alone).

Posted by on June 3rd, 2019

By Miriam Rosenberg and Suparna Ray Most of what we know about axial patterning in insects comes from decades of careful, beautiful work done in flies. Thanks to the genetic screens of Christiane Nüsslein-Volhard and Eric Wieschaus in the late 1970’s, we learned that distinct classes of genes, many of them transcription factors, act in[…]

Publishing Fly Research

Posted by on May 9th, 2019

Back in January, The Cambridge Fly Club held a symposium to mark 25 years since the publication of the famous Gal4/UAS paper (Brand & Perrimon, 1993 – published in Development); the organisers have posted a meeting report here. As part of this symposium, the organisers asked me to give a talk on ‘Publishing Fly Research’.[…]