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An evolutionary fable: the black pencil and the rubber.

Posted by on June 18th, 2020

By Héloïse Dufour, Shigeyuki Koshikawa and Cédric Finet In this post we will discuss our recent paper entitled “Temporal flexibility of gene regulatory network underlies a novel wing pattern in flies” [1]. We initiated the present project in Sean Carroll’s lab where the pigmentation in drosophilids was used as a model to study evolutionary genetics.[…]

Postdoctoral research fellow position in stem cells and regeneration- Patel lab U. of Bristol

Posted by on June 12th, 2020

We are looking for a highly motivated, intellectually curious and creative postdoctoral research fellow with a strong interest in tissue maintenance, regeneration and ageing to join our lab.   The Patel lab at the School of Cellular and Molecular Medicine, University of Bristol studies how tissues regenerate themselves after damage and how they maintain themselves[…]

3-year PhD Project on “Transcriptional regulation of intestinal stem cells during ageing”

Posted by on June 9th, 2020

The Korzelius lab has a funded position for a 3-year PhD at the University of Kent in Canterbury, U.K. We use the Drosophila intestine as a model system for age-related decline of organ function. Similar to the mammalian small intestine and colon, the fly intestine is maintained by a population of adult Intestinal Stem Cells[…]

Dissecting modes of pattern formation using live imaging and Hidden Markov Models

Posted by on April 30th, 2020

Background/History In the early fly embryo, information encoded in a handful of maternally deposited protein gradients is fed forward through increasingly intricate layers of interacting genes, culminating in the differentiation of the embryo into functional body segments with a high degree of spatial and temporal precision[1],[2]. Short segments of regulatory DNA known as enhancers lie[…]

Irin ajo mi si Nigeria | My journey to Nigeria

Posted by on April 17th, 2020

My first impression of Nigeria remained loyal to what I would experience the following two weeks: very warm weather, very colourful attires, very warm and joyful hearts. Also, it is loud, there is always sound…

PhD Studenship in soma-germline communication and signaling regulation in the Drosophila testis (Medway School of Pharmacy, Universities of Kent and Greenwich)

Posted by on February 13th, 2020

A PhD position is available in the lab of Fani Papagiannouli (@Medway School of Pharmacy, Universities of Kent and Greenwich) to study soma-germline communication and the role of cortical polarity in signaling regulation during Drosophila spermatogenesis. The position is funded by a Medway School of Pharmacy Post Graduate Research Scholarship.  Stem cells are critical for[…]

BSDB Gurdon/The Company of Biologists 2019 Summer Studentship Report – Jake Cornwall Scoones

Posted by on January 29th, 2020

Established by the British Society for Developmental Biology in 2014, The Gurdon/The Company of Biologists Summer Studentship scheme provides financial support to allow highly motivated undergraduate students an opportunity to engage in practical research during their summer vacation. Each year, ten successful applicants spend eight weeks in the research laboratories of their choices, and the feedback[…]

Off and On: it’s more complicated than we thought.

Posted by on January 23rd, 2020

We learn fairly early on when becoming biologists that both development and an organism’s response to environmental stressors require turning the right set of genes on in the right cells, at the right time. Clearly, for “on” to be meaningful, other genes have to be “off,” and many disordered conditions are associated with misexpression of[…]

BSDB Gurdon/The Company of Biologists 2019 Summer Studentship Report – Lauren Mulcahy

Posted by on January 18th, 2020

Established by the British Society for Developmental Biology in 2014, The Gurdon/The Company of Biologists Summer Studentship scheme provides financial support to allow highly motivated undergraduate students an opportunity to engage in practical research during their summer vacation. Each year, ten successful applicants spend eight weeks in the research laboratories of their choices, and the feedback[…]

Post-doctoral position: Chromatin dynamics in early embryogenesis.

Posted by on December 5th, 2019

The Blythe Lab at Northwestern University seeks to recruit a motivated postdoctoral fellow to investigate chromatin dynamics in early Drosophila embryogenesis.   Research in the Blythe Lab focuses on a critical period of embryogenesis termed the maternal-to-zygotic transition (MZT). During this time, embryos establish an initial ‘ground state’ of chromatin structure that defines the initial[…]