the community site for and by developmental biologists

Displaying posts with the tag: crispr [Clear Filter]

Postdoctoral Fellow Position – Genetics of Congenital Craniofacial and Neurodevelopment Malformations

Posted by on October 10th, 2017

An NIH-funded Postdoctoral Research Associate position is available in the Stottmann lab in the Divisions of Human Genetics and Developmental Biology.  Our interests are in the genetic basis of congenital malformations affecting the forebrain and craniofacial structures. Projects involve characterizing novel genes and mutations identified through forward genetic approaches in both mouse and human. We[…]

Research assistant in Development Biology, Sheffield University

Posted by on August 3rd, 2017

A Wellcome Trust/Royal Society funded Research Assistant position is available in Dr Kyra Campbell’s research group. This is a fantastic opportunity to join the Campbell group, who are focused on identifying the molecular mechanisms underlying epithelial cell plasticity during development and disease. We study how this fundamental property is orchestrated during morphogenesis of the Drosophila[…]

Reactions to the CRISPR human embryo paper

Posted by on August 3rd, 2017

A paper published online yesterday in Nature (and ‘leaked’ a week ago by the MIT Technology Review) describes the use of CRISPR in human embryos to correct a mutation that causes hypertrophic cardiomyopathy. The work has hit the headlines and sparked debate about its utility and implications. Collated below are responses from the field (or[…]

Postdoctoral position in chromatin and epigenetic control of Drosophila development

Posted by on June 30th, 2016

Stockholm University, Sweden, invites applications for one postdoctoral position in the laboratory of Professor Mattias Mannervik at the Department of Molecular Biosciences, The Wenner-Gren Institute (http://www.su.se/mbw). The position is scheduled to start as soon as possible.   Transcriptional coregulators are proteins that facilitate communication between transcription factors and the basal transcription apparatus, in part by[…]

2016 CSHL Xenopus Course (last few spots!) Deadline Feb 21

Posted by on February 12th, 2016

In order to encourage applicants to the 2016 Xenopus Course at Cold Spring Harbor, we able to offer substantial support to offset course costs thanks to support from the NICHD, Helmsley Charitable Trust, and HHMI to eligible candidates. We are particularly interested in scientists with an interdisciplinary or non-traditional background, or scientists new to Xenopus.[…]

Question of the month- patenting public research

Posted by on January 29th, 2016

Last week the Montreal Neurological Institute announced that it will become the first fully Open Science academic institute. In addition to  making their results and data available for free upon publication, this initiative also includes a  commitment not to register patents on any of their discoveries. This announcement comes in contrast with the ongoing heated dispute on[…]

Question of the month- CRISPR technology

Posted by on April 23rd, 2015

This week a group in China published a paper in Protein & Cell claiming to have genetically edited a human embryo using CRISPR technology. This paper is generating a lot of debate for many reasons, from the type of embryo used in the experiment, to where it was (or wasn’t) published. More broadly though, it forces us to think about[…]

Postdoctoral scientist position in Genome Editing in Xenopus at the Marine Biological Laboratory

Posted by on February 25th, 2015

A Postdoctoral Scientist position is available in the Horb Laboratory of the Eugene Bell Center for Regenerative Biology & Tissue Engineering at the Marine Biological Laboratory (http://www.mbl.edu/horb/). The position will focus on the creation of Xenopus models of human disease through the generation of mutants using CRISPR/Cas and TALENs and to work on developing and[…]

Tissue-specific genome editing in Ciona embryos by CRISPR/Cas9

Posted by on October 31st, 2014

Researchers have always been interested in tissue-specific loss of function to probe the role of specific genes in embryonic development, cell physiology and disease conditions. Migration of lateral plate primordial germ cells in zebrafish, border cell migration during oogenesis in drosophila, interaction of T-cells with their target, and numerous other cases have continued to give[…]