the community site for and by developmental biologists

Displaying posts with the tag: zebrafish [Clear Filter]

Ph.D. positions in Developmental Biology, Morphogenesis, Cardiovascular Biology-University of Mississippi

Posted by on October 13th, 2017

  Our research seeks to investigate the fundamental question of how cardiac cells sense and respond to their environment. Focusing on tissue interactions we seek to understand the mechanisms underlying the regulation of morphogenic and identity transformations that occur during development and disease. We use the assembly of the heart tube in zebrafish as our[…]

Two fully-funded PhD positions in Wnt trafficking at the LSI in Exeter

Posted by on October 9th, 2017

The process of subdividing a tissue into functional units represents a classic problem in pattern formation. Signalling proteins – so-called morphogens – orchestrate this process. The traditional view is that morphogens are released from local source and slowly diffuse through a neighbouring tissue to build up a gradient. As Wnt signals act as a key[…]

Discovery Through Collaboration: Brain Lymphatic Endothelial Cells

Posted by on August 8th, 2017

Looking back on the journey: Intracellular uptake of macromolecules by brain lymphatic endothelial cells during zebrafish embryonic development eLife van Lessen et al., 2017   Just over two years ago, while I was a Masters of Neuroscience student at University College London, I became interested in the emerging concepts of brain lymphatics and sleep dependent macromolecule[…]

The people behind the papers: Gabriel Krens and Carl-Philipp Heisenberg

Posted by on May 25th, 2017

Cell sorting is a critical process during development, as differently specified cells are segregated to the right parts of the embryo. Differences in cell adhesion and cortical tension are thought to be crucial to this process, but the mechanics have been difficult to probe in vivo. This week’s paper, published in the current issue of[…]

Biotagging: Behind the scenes (and beyond)

Posted by on May 16th, 2017

“It finally got accepted!”, fol­­lowed by “It’s finally out!” about a month later. I am certain this ‘finally’ feeling about their paper is very familiar to those well-acquainted with the peer review process, and it was no different for our recently published Resource article. The ‘biotagging paper’, as we call it within the Sauka-Spengler lab,[…]

The people behind the papers: Dae Seok Eom & David Parichy

Posted by on April 7th, 2017

Macrophages are usually associated with immunity, but have increasingly appreciated functions in development and homeostasis. This week we meet the authors of a recent Science paper that identified a role for macrophages in zebrafish stripe patterning, revealing a remarkable ‘relay’ mechanism whereby macrophages help one type of cell signal to another via cytoplasmic extensions. Postdoc[…]

Biologists find ‘skin-and-bones’ mechanism underlying zebrafish fin regeneration

Posted by on March 28th, 2017

This Press Release from the University of Oregon was originally posted on Eurekalert.   EUGENE, Ore. March 28, 2017 University of Oregon biologists have figured out how zebrafish perfectly regenerate amputated fins with a precisely organized skeleton. Adult zebrafish fins, including their complex skeleton, regenerate exactly to their original form within two weeks after an[…]

New signal revealed for birth of blood stem cells in vertebrates

Posted by on March 1st, 2017

Jamie R. Genthe and Wilson K. Clements   When blood goes bad, a replacement is often needed. Each year, thousands of patients in the US receive bone marrow transplants to treat life-threatening diseases like blood cancer. But in some cases, the transplant itself can become deadly. The problem is not necessarily the one most people think[…]

Diversity is a good thing: coordination of collective cell migration in angiogenesis

Posted by on February 2nd, 2017

Comment on “Asymmetric division coordinates collective cell migration in angiogenesis” Nat Cell Bio, 18 (12), 1292-1301, (2016).   Holly E. Lovegrove & Guilherme Costa Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, Uk   Collective cell migration is involved in many biological processes. In particular it is required to build new tissues[…]

The tale of three cities – Valdivia, Jyväskylä and London

Posted by on January 23rd, 2017

This is the latest dispatch from a recipient of a Company of Biologists Travelling Fellowship. Learn more about the scheme, including how to apply, here, and read more stories from the Fellows here. Hanna Hakkinen   I am originally a Finnish evolutionary biology student who got fascinated about developmental biology during my exchange programme couple of[…]