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BSDB/GenSoc 2020 Poster Session II

Posted by , on 17 March 2020

Here’s the second poster session of the virtual BSDB / Genetics Society 2020 meeting. The presenters would love to hear your comments and questions

 

1. Rebecca Lea (The Francis Crick Institute)

‘Identifying novel regulators of human pluripotency and embryogenesis’.

 

Fighsare link

 

2. Lara Busby (University of Cambridge)

‘Investigating time & cell fate decisions in the development of the avian posterior body’

 

Figshare link

 

3. Christian Schröter (MPI Dortmund)

‘Generation and maintenance of robust cell fate proportions by FGF/ERK signaling’

 

Figshare link

 

4. William Hamilton (DanStem)

‘Category errors in the pluripotency network’

 

Figshare link

 

5. Tim Fulton (University of Cambridge)

‘Self-organised symmetry breaking in zebrafish reveals feedback from morphogenesis to pattern formation’

 

Figshare link

 

6. Clare Benson (University of London)

‘Investigating Rho dysregulation in Adams-Oliver syndrome as a model of vascular development’

 

Figshare link

 

 

7. Monika Fluks (University of Warsaw)

‘Glucose import efficiency is reduced in transcriptionally active mouse GV oocytes’

 

 

Figshare link

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Scientist/Post-doctoral Associate position in leukemic stem cells and metabolism is available at the University of Bern, Switzerland

Posted by , on 16 March 2020

Closing Date: 15 March 2021

Scientist/Post-doctoral Associate position (100%) is available in the laboratory of ‘’Stem Cells and Leukemia’’ at the University Clinic of Hematology & Central Hematology, Department of Biomedical Research (DBMR), Inselspital Bern, Switzerland. We are looking for a highly motivated and creative scientist with a PhD or MD/PhD degree to contribute to research projects aiming to explore leukemic stem cell dependencies and vulnerabilities using transgenic mouse models of myeloid malignancies and primary patient samples from leukemia patients. The project is supported by Swiss National Science Foundation (SNSF). The employment starting date is 01.05.2020 (or negotiable).

 

Your profile

The potential candidate must be experienced in working with transgenic mouse models, primary patient samples and multicolor flow cytometry. Expertise in working with blood stem cells, and a strong background in cancer biology and/or metabolism is preferred. Demonstrated competence to independently conduct experiments and analyses, and willingness to collaborate internally and externally is mandatory. Applicant should have an excellent command of spoken and written English.

 

We offer you

The post-holder will be supported by a well-funded interdisciplinary research project in a young and dynamic environment. Our team works closely with clinicians and pharma industries in Switzerland and abroad. Department of Biomedical Research (DBMR) at the University of Bern and Inselspital Bern provides a stimulating environment and offers all the possibilities to be creative and highly productive. The position is limited to 3 years with a possibility of extension. The salary will be according to the guidelines of the SNSF.

 

Application / Contact

To apply for this position please submit your application in a single Pdf file including 1-page motivation letter specifying your research experience and interests, desired start date, CV, copies of PhD or MD/PhD degree, list of publications, and the names and contact details of 2-3 referees to: : tata.nageswararao@dbmr.unibe.ch

 

For further inquiries please contact:

Dr. Tata Nageswara Rao, PhD
Group leader
Stem Cells and Leukemia laboratory
University Clinic of Hematology
Department of Biomedical Research (DBMR)
Inselspital Bern, University of Bern
Murtenstrasse 40, 3008, Bern, Switzerland

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BSDB/GenSoc 2020 Poster Session I

Posted by , on 16 March 2020

The online version of the BSDB Genetic Society Spring meeting is well on its way over on Twitter (follow it at #BSDBGenSoc2020 and see our recently updated post for details about what we’re planning over the next couple of days).

Here we’re going to share the e-Poster session – 12 participants uploaded the posters they were due to present in Warwick to figshare. In the gallery below you’ll find images of the posters plus links to the high res versions and descriptions. Good poster sessions involve dialogue, and we’re hoping that some of you will reach out to the poster presenters with questions or comments – you can leave a comment here or on Twitter or contact them via the email addresses on the posters.

For participants who had a poster ready but have yet to upload it – there’s still time to join the second poster session tomorrow – just upload your poster to figshare and email thenode@biologists.com to tell us about it.

 

 

 

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eBSDB/GenSoc 2020 plans

Posted by , on 14 March 2020

 

UPDATE 16 MARCH events timetable added below

Following the cancellation of BSDB/GenSoc2020, the meeting organisers have been seeking ways to maintain some elements of the meeting through online interactions. We do not plan to run a full virtual meeting, but we do plan to experiment with ways to recreate some of the useful and fun parts of the meeting online.

The activities will run from Monday 16 – Wednesday 18 March.

Timetable-in-progress

Check back for updates

Timings are for UK time (GMT)

Monday

12 -2pm          Poster session

3pm               Waddington Medal Winner annoucement

6pm                Tickle Medal Winner announcement

Tuesday

11am              Virtual Careers Session run by @BSDBgradstudent

12 -2pm         Poster session

3pm                Beddington Medal winner announcement

6pm                Conference party! Kitchen-dancing to the Spotify playlist at the end of this post

PLUS…Posters, talks, interviews, competitions and more will be linked to from @the_Node and can also be found using #BSDBGenSoc2020 throughout the e-meeting.

Here are the various various ways you can get involved:

Twitter

The best way to get involved is via Twitter, where you can follow the hashtag #BSDBGenSoc2020. The BSDB medal winners will also be announced on Twitter, and you will have a chance to interact with speakers and poster presenters. If you don’t have a Twitter account why not consider getting one?

 

Upload your talks/posters

If you’re disappointed about not being able to share your work in Warwick, why not share it online? This is a great opportunity, particularly for students and postdocs, to promote their work despite the cancellation of the meeting.

  • Upload the talk slides/posters you were scheduled to give to figshare.
  • Use #BSDBGenSoc2020 as a keyword so others can find it easily, and don’t forget to include contact details so interested parties can get in touch.
  • Once you’ve uploaded your files, email the figshare link to thenode@biologists.com, and we’ll collate the documents into a Node post and help promote them on Twitter. The first 20 people to tell us about their uploads will get some goodies from The Company of Biologists!

 

Virtual talks

Speakers – in addition to thinking about sharing your slides, you could consider:

  • A Tweetorial – a thread covering the talk, including some choice images/slides, visual abstracts or GIFs. See this great recent example from Jesse Venvliet
  • Recording your talk on Powerpoint (see how to) or using a webcam or camera. If you do this, send us the file or a link and we will help promote it

 

Interviews and workshops

We hope to be posting interviews with medal winners and other speakers and there will be the chance to take part in our Careers workshop online…stay tuned for more

 

Interact

We strongly encourage everyone to send comments and questions to presenters of online posters and talks, whether publicly (e.g. through Twitter) or privately (by email to the presenter). This will help recapture the spirit of the BSDB meeting and give valuable feedback, especially to early career researchers.

 

Image competition

Tweet your favourite image from a talk or poster that you would have presented at #eBSDBGenSoc2020. The image caption should be contained within a single tweet along with the hashtag #eBSDBimages. Deadline noon 18 March!

 

Devbio on the dancefloor

Tweet your favorite song with #electroBSDB and we will add it to the eBSDB party playlist (or you should be able to add it directly yourself if you have a Premium account). Which track do you look forward to DJ Phil playing each year? Any guilty pleasures?

 

 

 

 

The BSDB and GenSoc are hugely grateful to the editors at Development and The Node for initiating these plans, providing expertise and infrastructure, and for their generous offer to put in the considerable amount of work to make this happen. Yet another reason to support your community journal!

 

 

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Genetics Unzipped: Is there such a thing as a perfect genome? Myths and misconceptions in genomics

Posted by , on 13 March 2020

Shocked small boy

In this episode, in partnership with the Genomics Education Programme’s Week of Action (16th-20th March), we’re taking a look at some of the common myths and misconceptions surrounding genomics and genetic tests. Are mutations always bad? If you’re more like your mum, does that mean you’ve inherited more of her genes? And is there such a thing as a perfect genome?
Join the conversation by following @genomicsedu and #GenomicsConversation on Twitter or head over to genomicseducation.hee.nhs.uk
“It is certainly as true as the gospel that when a man sleeps with his wife or his mistress with dirty and smelly feet, if he fathers a boy, the child will have smelly and unpleasant breath. If he fathers a girl, she will have a stinky rear end.”
There are lots of strange ideas about inheritance out there in the world. That one is from the Distaff Gospels – a collection of medieval old wives’ tales. Pregnant women were also advised to avoid eating hares in case they caused their baby to be born with a cleft palate and to skip snacking on fish heads in case their child ended up with a trout pout.
Fortunately, our understanding of inheritance has moved on a bit since then. Genetics and genomics are playing ever more important roles in modern healthcare. Genetic tests – and increasingly, more detailed genomic analysis – are providing an unprecedented amount of information about the underlying genetic variations and alterations that affect health.

Go to GeneticsUnzipped.com to listen or download and to get a full transcript, links and references.

Genetics Unzipped is the podcast from The Genetics Society. Subscribe from Apple podcasts/iTunes, Spotify and all good podcast apps to make sure you get the latest episodes and catch up on our back catalogue.

If you enjoy the show, please do rate and review on Apple podcasts and help to spread the word on social media. And you can always send feedback and suggestions for future episodes and guests to podcast@geneticsunzipped.com Follow us on Twitter – @geneticsunzip

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Labs in lockdown

Posted by , on 13 March 2020

The coronavirus pandemic has led to travel restrictions, conference cancellations and university closures. How do labs function in various states of lockdown? What happens to model organisms and long running experiments? On the personal side, how can we counter the loss of lab camaraderie? And education – how can you run a course from home?

Here, we’ve collated a bunch of Twitter threads that deal with some of these issues, which hopefully will be relevant to many of you. If you have any questions for the community, or plans you would like to share, we’d love to hear from you – just comment below the post, or register here to write your own post.

 

This thread from Alex Shier’s lab on March 8 described how the lab would be working from now on.

 

Can we run labs on one person shifts?

https://twitter.com/JJ_Emerson/status/1237784345751867392

 

The Soragni lab is moving remotely as much as possible

 

How Stephen Floor’s lab are approaching working from home

 

Maren Friesen shared her coronovirus lab plans:

 

Suspending lab access in Harvard:

 

Giulia Biffi, a PI in Cambridge:

 

A plea to funding bodies to consider mitigating actions

 

Lots of ideas in this tweet and replies.

 

The Yaniv lab is Staying positive

 

 

The Gallego lab is using the lockdown as a chance to become better, computationally speaking

 

48 hours to shut down the Bardelli lab in Italy

 

And, please don’t do this, PIs!

 

A thread on zebrafish emergency preparedness

 

 

Seems like C. elegans researchers are a little less worried!

 

To fight social isolation, why not set up a virutal coffee break?

 

Or a virtual happy hour?

https://twitter.com/JShendure/status/1237640592147931136

 

Keep educating: a thread on how to use Zoom to lecture from home

 

A perspective on online learning from the Open University

 

Online courses could help fill your days

 

Cancelled conferences? Why not share your talk and poster online:

 

Indeed we are planning to help with this for the BSDB Spring meeting, which would have started on Sunday. More info here:

eBSDB/GenSoc 2020 plans

 

Virtual seminar series – more ideas in the replies

 

Help for conference organisers from OSF

 


Please let us know if you find any other useful links.

 

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BSDB meeting cancelled

Posted by , on 10 March 2020

Here at the Node and Development, the BSDB Spring meeting is always the first thing to go into our conference calendar, as an institution for the UK developmental biology community. The 2020 meeting, co-organised with the Genetics Society and due to start on Sunday, has just been cancelled due to concerns about spread of Covid-19 (more info will be available soon and we’ll share it here). It joins other recently cancelled developmental biology conferences (such as those in EMBL Heidelberg and Keystone). It seems to us to have been an inevitable decision, if a sad one, and we look forward to the next time a few hundred developmental biologists get together in the bar in Warwick!

Some photos of the last two meetings, ripped from Twitter:

 

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Postdoctoral fellowship at UPSC (Sweden) on Plant metacaspases and vascular development

Posted by , on 8 March 2020

Closing Date: 15 March 2021

The fellowship is a part of a 5-year project “ Co-evolution of metacaspase structure and biological function in Arabidopsis”, which aims to advance our mechanistic understanding of metacaspase family proteases in close cooperation between five research groups located in Uppsala BioCenter at SLU, Umeå SLU and Umeå University. The successful candidate for this fellowship will join the group of Hannele Tuominen at UPSC in Umeå, Sweden.

Umeå Plant Science Centre (UPSC) is a research centre in Umeå, Sweden (www.upsc.se) where research of both basic and strategic importance is conducted. The research at UPSC is carried out on all organization levels of the plant with a common goal to understand the plant as a complex organism in dynamic interaction with its environment.

Previous studies carried out by the host and other laboratories have linked metacaspases to regulation of aging and cell death in diverse organisms (Escamez et al., 2020). The Arabidopsis thaliana Metacaspase9 (MC9) is required for the rapid autolysis of the xylem vessel elements (Bollhöner et al., 2013), but the underlying mechanism as well as the proteolytic substrates of MC9 remain poorly understood. The main purpose of this project is to study MC9-mediated cleavage of target proteins which results in production of biologically active peptides, including the previously identified Bia and Kratos peptides (Escamez et al., 2019, J Exp Bot. 70:2199-2210). The function of the peptides is investigated in vascular differentiation of Arabidopsis using genetic, proteomic and biochemical methods. Other aspects of the project can be developed according to the interests of the candidate.

  • Bollhöner B, Zhang B, Stael S, Denancé N, Overmyer K, Goffner D, van Breusegem F and Tuominen H 2013. Post mortem function of AtMC9 in xylem vessel elements. New Phytologist 200:498-510.
  • Escamez S, Stael S, Vainonen J, Willems P, Jin H, Kimura S, Van Breusegem F, Gevaert K, Wrzaczek M, and Tuominen H. 2019. Extracellular peptide Kratos restricts cell death during vascular development and stress in Arabidopsis. Journal of Experimental botany 70: 2199–2210.
  • Escamez S, André D, Sztojka B, Bollhöner B, Hall H, Berthet B, Voss U, Lers A, Maizel A, Andersson M, Bennett M, Tuominen H. 2020. Cell death in cells overlying lateral root primordia contributes to organ growth in Arabidopsis. Current Biology 30: 1–10.

We are looking for a highly motivated plant biologist with a keen interest in understanding mechanisms and role of proteolysis in a developmental context. Successful candidates are expected to have a PhD degree, experience in cell and molecular biology and genetics, and a proven research track record.

A stipend is granted for 2 years starting in August 1, 2020 or by agreement. The tax-free stipend is financed by the Wallenberg foundation and amounts to 288 000 SEK per year. The fellowship can be prolonged by a two-year University employment after positive evaluation. The project involves visits to collaborating laboratories.

Please send you application, including a personal letter, CV, and contact information of three references by e-mail to Hannele.tuominen@slu.se latest 30 April 2020.

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Call for letter of interest: Executive Director to DanStem, University of Copenhagen

Posted by , on 6 March 2020

Closing Date: 15 March 2021

A Directorship position is now open at the Novo Nordisk Foundation Center for Stem Cell Biology DanStem Faculty of Health and Medical Sciences, University of Copenhagen
DanStem is seeking a visionary scientific leader of international stature with a strong track record of innovative research in developmental and stem cell biology.
DanStem is dedicated to promoting research in stem cell and developmental biology within Denmark and throughout Europe. A part of this commitment involves the training of the next generation of stem cell scientist. To this end DanStem engages in pre-graduate training, operates a four-year PhD program, offers a broad spectrum of post-graduate teaching and a number of out-reach activities. DanStem also engages in active post-doctoral training and mentorship programs. Together with its large post-graduate and post-doctoral population, DanStem represents a major European hub for training in contemporary stem cell biology.
DanStem is a part of the NNF Center Cluster, that also contains the Centers for Protein Research (CPR), Basic Metabolic Research (CBMR) and Biosustainability.
Read more about the position and recruitment process

Image

 

For informal inquiries and more information about position, you are welcome to contact:

Dean Ulla Wewer (dekan@sund.ku.dk),

Professor Tor Henrik Semb (semb@sund.ku.dk)

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Call for letter of interest – Executive Director (Professor) of the Novo Nordisk Foundation Center for Stem Cell Biology (DanStem)

Posted by , on 6 March 2020

Closing Date: 15 March 2021

DanStem
The Novo Nordisk Foundation Center for Stem Cell Biology (DanStem) addresses fundamental research questions in stem cell and developmental biology and seeks to develop translational activities based on this fundamental discovery science, producing new therapeutic strategies for chronic diseases. Current focus at DanStem is predominantly on fundamental research at the highest level, and the Center also offers investigators the opportunity to develop their work in the translational arena, providing opportunities for strategic development aiming at clinical application. DanStem is a vibrant, internationally diverse and ambitious research center with state-of-the-art facilities located at the Faculty of Health and Medical Sciences, University of Copenhagen. The setting is ideally situated for seamless collaboration and exchange with other centers and departments of the Faculty and the surrounding hospitals
DanStem is dedicated to promoting research in stem cell and developmental biology within Denmark and throughout Europe. A part of this commitment involves the training og the next generation of stem cell scientist. To this end DanStem engages in pre-graduate training, operates a four-year PhD program, offers a broad spectrum of post-graduate teaching and a number of out-reach activities. DanStem also engages in active post-doctoral t5raining and mentorship programs. Together with its large post-graduate and post-doctoral population, DanStem represents a major European hub for training in contemporary stem cell biology.

Learn more about DanStem at https://danstem.ku.dk/.

DanStem is a part of the NNF Center Cluster, that also contains the Centers for Protein Research (CPR), Basic Metabolic Research (CBMR) and Biosustainability. Three of these centers are located in the Faculty of Health and Medical Science at the University of Copenhagen. DanStem is situated in the Panum building along with CPR, with whom it shares research technology platforms. DanStem is also on the same campus as CBMR and a number of other relevant departments in biomedical sciences. A short walking distance from DanStem is the Biotech Research and Innovation Center (BRIC), a high-profile, vibrant and international center for cancer and epigenetics research at the Faculty, where some of the DanStem research programs are based.  As a result of DanStem’s proximity, there is ample opportunity for educational and research collaborations. DanStem is well integrated into European science and recognized internationally as a key player in stem cell research.

DanStem is a highly international and rewarding workplace with a staff of 250, placing high value on diversity and synergistic approaches to solving the challenges of developmental and stem cell biology. As DanStem has evolved in the last ten years its research approaches have become increasingly interdisciplinary and quantitative. Its location next to the Niels Bohr Institute and in close proximity to Denmark’s leading technical university (Danish Technical University) has helped enable this transition. Importantly, while DanStem will continue solving fundamental questions in stem cell biology, the future will emphasize and strengthen translational stem cell-based applications. This will be enabled through the Faculty’s strong collaboration with the hospitals.

DanStem Executive Directorship
Qualified Executive Director candidates will be visionary scientific leaders of international stature with a strong track record of innovative research in developmental and stem cell biology. They will also have the vision to identify and support new translational programs aiming at clinical application. They are expected to have a strong track record of collaboration and a history in building interdisciplinary academic research in a collaborative environment. The Executive Director will lead the overall research directions at the Center and promote the research carried out by DanStem’s faculty. A management team and Scientific Advisory Board support the Executive Director.

Expectations
The Executive Director will:

  • Be responsible for development of the Center, including producing and implementing a vision for future scientific growth as well as the recruitment of a new generation of outstanding and highly interactive researchers
  • Lead her/his own research group
  • Develop new strategic initiatives and support existing and future translational programs
  • Participate in fostering new collaborations
  • Work closely with key scientific and administrative staff to develop a comprehensive research strategy and guide the future direction of DanStem’s research portfolio
  • Collaborate on cross center initiatives with CPR and CBMR, as well as other national and international research centers
  • Report to the Dean of the Faculty of Health and Medical Sciences and work closely with Dean’s office in a variety of joint efforts including educational activities
  • Lead the writing of the strategic application to NNF for funding of the renewal period (8 years).


Qualifications and experience

The successful candidate will:

  • Hold an appropriate doctoral degree
  • Have an outstanding record of scientific discovery and accomplishment, including a track record of substantial external competitive funding and proven success in collaborations
  • Present a clear vision of future directions in areas related to developmental and stem cell biology, including how fundamental science can provide technological innovation and clinical translation
  • Demonstrate excellent interpersonal and leadership skills, especially with regard to successful leadership of international and diverse teams
  • Proven management skills
  • Show a commitment to foster and promote excellence in scientific research and education


Inquiries

For informal inquiries and more information about position, you are welcome to contact Dean Ulla Wewer (dekan@sund.ku.dk),  Professor Tor Henrik Semb (semb@sund.ku.dk) or Perrett Laver (see contact information below).


Submitting letter of interest

Perrett Laver is assisting the search committee with the recruitment process. Perrett Laver may also be contacted for informal inquiries and questions on Jack.Bircher@perrettlaver.com or +44 (0)20 7340 6275. Further information, including details on how to apply, can be downloaded at https://candidates.perrettlaver.com/vacancies/ quoting reference 4558.

Please include the following documents, when submitting your letter of interest:

  • Your curriculum vitae, detailing employment history, and academic and professional qualifications (max. 4 pages including bio sketch)
  • A description of your vision for the future of developmental and stem cell biology and how you believe DanStem could contribute to this  (max. 5 pages)
  • A list of not more than 10 selected publications
  • A link or reference to a complete list of publications (e.g. ORCID).


Deadline for submitting letters of interest: April 15th 2020 at 23:59 CET.

For further information about

 

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

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