Scientist/Post-doctoral Associate position (100%) is available in the laboratory of ‘’Stem Cells and Leukemia’’ at the University Clinic of Hematology & Central Hematology, Department of Biomedical Research (DBMR), Inselspital Bern, Switzerland. We are looking for a highly motivated and creative scientist with a PhD or MD/PhD degree to contribute to research projects aiming to explore leukemic stem cell dependencies and vulnerabilities using transgenic mouse models of myeloid malignancies and primary patient samples from leukemia patients. The project is supported by Swiss National Science Foundation (SNSF). The employment starting date is 01.05.2020 (or negotiable).

Your profile

The potential candidate must be experienced in working with transgenic mouse models, primary patient samples and multicolor flow cytometry. Expertise in working with blood stem cells, and a strong background in cancer biology and/or metabolism is preferred. Demonstrated competence to independently conduct experiments and analyses, and willingness to collaborate internally and externally is mandatory. Applicant should have an excellent command of spoken and written English.

We offer you

The post-holder will be supported by a well-funded interdisciplinary research project in a young and dynamic environment. Our team works closely with clinicians and pharma industries in Switzerland and abroad. Department of Biomedical Research (DBMR) at the University of Bern and Inselspital Bern provides a stimulating environment and offers all the possibilities to be creative and highly productive. The position is limited to 3 years with a possibility of extension. The salary will be according to the guidelines of the SNSF.

Application / Contact

To apply for this position please submit your application in a single Pdf file including 1-page motivation letter specifying your research experience and interests, desired start date, CV, copies of PhD or MD/PhD degree, list of publications, and the names and contact details of 2-3 referees to: : tata.nageswararao@dbmr.unibe.ch

For further inquiries please contact:

Dr. Tata Nageswara Rao, PhD
Group leader
Stem Cells and Leukemia laboratory
University Clinic of Hematology
Department of Biomedical Research (DBMR)
Inselspital Bern, University of Bern
Murtenstrasse 40, 3008, Bern, Switzerland

(2 votes)

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The online version of the BSDB Genetic Society Spring meeting is well on its way over on Twitter (follow it at #BSDBGenSoc2020 and see our recently updated post for details about what we’re planning over the next couple of days).

Here we’re going to share the e-Poster session – 12 participants uploaded the posters they were due to present in Warwick to figshare. In the gallery below you’ll find images of the posters plus links to the high res versions and descriptions. Good poster sessions involve dialogue, and we’re hoping that some of you will reach out to the poster presenters with questions or comments – you can leave a comment here or on Twitter or contact them via the email addresses on the posters.

For participants who had a poster ready but have yet to upload it – there’s still time to join the second poster session tomorrow – just upload your poster to figshare and email thenode@biologists.com to tell us about it.

Davide Marchi ‘Bidirectional crosstalk between hypoxia-inducible factor and glucocorticoid signalling in zebrafish larvae’ https://figshare.com/articles/HIF-GC_crosstalk-DM_Poster_pdf/11987322/1

Filipa Simões ‘Macrophages directly contribute collagen to scar formation during heart repair and regeneration’ https://figshare.com/articles/Macrophages_directly_contribute_collagen_to_scar_formation_during_heart_repair_and_regeneration/11977344/1

Gabriela Toro-Tapia ‘Primary cilium remodelling mediates a cell signalling switch in differentiating neurons’ https://figshare.com/articles/Toro-Tapia_poster_BSDB/11981061

Jake Cornwall Scoones ‘A dot-stripe Turing model of joint patterning’ https://figshare.com/articles/A_dot-stripe_Turing_model_of_joint_patterning_in_the_tetrapod_limb/11982165

Mattias Malaguti ‘Id1 stabilises epiblast identity during peri-implantation development by modulating signal responsiveness’ https://figshare.com/articles/Id1_stablises_epiblast_identity_during_peri-implantation_development_by_modulating_signal_responsiveness/11987505

Michael Weinberger ‘Functional heterogeneity within the developing zebrafish epicardium’ https://figshare.com/articles/Functional_heterogeneity_in_the_developing_zebrafish_epicardium/11984187

Monika Fluks ‘Optical coherence microscopy as a label-free tool for imaging live oocytes and embryos’ https://figshare.com/articles/Optical_coherence_microscopy_as_a_label-free_tool_for_imaging_live_oocytes_and_embryos/11987250

Joaquin Lilao-Garzon ‘Fertibetes: A new mouse model to study fertility in age obesity and diabetic context’ https://figshare.com/s/e45a58ae42b5bc01e0f8

Quentin Lemaitre ‘Investigating the role of Prdm14 in non-ectodermal neurogenesis of the sea anemone Nematostella vectensis’ https://figshare.com/s/2ab7426a7027f352894b

Ahlam Harasani ‘Epigenetic role of prc2 subunit ezh2 in embryo development’ https://figshare.com/articles/Epigenetic_Role_of_PRC2_Subunit_EZH2_in_Embryo_Development/11987931/1

Ana Jones ”Exploring the curves of the zebrafish inner ear’ https://figshare.com/s/bff451c1301586801f39

(1 votes)

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UPDATE 16 MARCH events timetable added below

Following the cancellation of BSDB/GenSoc2020, the meeting organisers have been seeking ways to maintain some elements of the meeting through online interactions. We do not plan to run a full virtual meeting, but we do plan to experiment with ways to recreate some of the useful and fun parts of the meeting online.

The activities will run from Monday 16 – Wednesday 18 March.

Timetable-in-progress

Check back for updates

Timings are for UK time (GMT)

Monday

12 -2pm          Poster session

3pm               Waddington Medal Winner annoucement

6pm                Tickle Medal Winner announcement

Tuesday

11am              Virtual Careers Session run by @BSDBgradstudent

12 -2pm         Poster session

3pm                Beddington Medal winner announcement

6pm                Conference party! Kitchen-dancing to the Spotify playlist at the end of this post

PLUS…Posters, talks, interviews, competitions and more will be linked to from @the_Node and can also be found using #BSDBGenSoc2020 throughout the e-meeting.

Here are the various various ways you can get involved:

Twitter

The best way to get involved is via Twitter, where you can follow the hashtag #BSDBGenSoc2020. The BSDB medal winners will also be announced on Twitter, and you will have a chance to interact with speakers and poster presenters. If you don’t have a Twitter account why not consider getting one?

Upload your talks/posters

If you’re disappointed about not being able to share your work in Warwick, why not share it online? This is a great opportunity, particularly for students and postdocs, to promote their work despite the cancellation of the meeting.

• Upload the talk slides/posters you were scheduled to give to figshare.
• Use #BSDBGenSoc2020 as a keyword so others can find it easily, and don’t forget to include contact details so interested parties can get in touch.
• Once you’ve uploaded your files, email the figshare link to thenode@biologists.com, and we’ll collate the documents into a Node post and help promote them on Twitter. The first 20 people to tell us about their uploads will get some goodies from The Company of Biologists!

Virtual talks

Speakers – in addition to thinking about sharing your slides, you could consider:

• A Tweetorial – a thread covering the talk, including some choice images/slides, visual abstracts or GIFs. See this great recent example from Jesse Venvliet
• Recording your talk on Powerpoint (see how to) or using a webcam or camera. If you do this, send us the file or a link and we will help promote it

Interviews and workshops

We hope to be posting interviews with medal winners and other speakers and there will be the chance to take part in our Careers workshop online…stay tuned for more

Interact

We strongly encourage everyone to send comments and questions to presenters of online posters and talks, whether publicly (e.g. through Twitter) or privately (by email to the presenter). This will help recapture the spirit of the BSDB meeting and give valuable feedback, especially to early career researchers.

Image competition

Tweet your favourite image from a talk or poster that you would have presented at #eBSDBGenSoc2020. The image caption should be contained within a single tweet along with the hashtag #eBSDBimages. Deadline noon 18 March!

Devbio on the dancefloor

Tweet your favorite song with #electroBSDB and we will add it to the eBSDB party playlist (or you should be able to add it directly yourself if you have a Premium account). Which track do you look forward to DJ Phil playing each year? Any guilty pleasures?

The BSDB and GenSoc are hugely grateful to the editors at Development and The Node for initiating these plans, providing expertise and infrastructure, and for their generous offer to put in the considerable amount of work to make this happen. Yet another reason to support your community journal!

(11 votes)

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“It is certainly as true as the gospel that when a man sleeps with his wife or his mistress with dirty and smelly feet, if he fathers a boy, the child will have smelly and unpleasant breath. If he fathers a girl, she will have a stinky rear end.”

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The coronavirus pandemic has led to travel restrictions, conference cancellations and university closures. How do labs function in various states of lockdown? What happens to model organisms and long running experiments? On the personal side, how can we counter the loss of lab camaraderie? And education – how can you run a course from home?

Here, we’ve collated a bunch of Twitter threads that deal with some of these issues, which hopefully will be relevant to many of you. If you have any questions for the community, or plans you would like to share, we’d love to hear from you – just comment below the post, or register here to write your own post.

This thread from Alex Shier’s lab on March 8 described how the lab would be working from now on.

Can we run labs on one person shifts?

https://twitter.com/JJ_Emerson/status/1237784345751867392

The Soragni lab is moving remotely as much as possible

Now this is not an easy decision, we are a wet lab almost exclusively, and a new one at that as we only opened the doors 3 years ago.
This break will come at a price. But societal risks are much more important than any single experiment and delay. So onwards and upwards we go.

— Soragni:Lab (@soragnilab) March 12, 2020

How Stephen Floor’s lab are approaching working from home

Maren Friesen shared her coronovirus lab plans:

Suspending lab access in Harvard:

So @Harvard science division is essentially shutting down research labs starting next week. At most 2-3 individuals per lab for maintaining cell/mouse lines. Expects suspended lab access to last *at least* 6-8 weeks pic.twitter.com/EyEWgXWrvY

— Tanush Jagdish (@TanushJagdish) March 12, 2020

Giulia Biffi, a PI in Cambridge:

Today I told my people to stop doing experiments and stay home. As a trainee, I know I would have been upset about this. As a PI, I cannot think about a good reason not to do it. I will carry on with their work (unless the institute shuts down). Stay well everyone.

— Giulia Biffi (@BiffiGiulia) March 12, 2020

A plea to funding bodies to consider mitigating actions

#Covid_19 must be affecting many labs. We have two major tumour studies now on hold indefinitely. This will impact timely publication and post-doc career progression. I hope @AMRC, @wellcometrust, #UKRI etc are considering mitigating actions.

— MossLabUCL #FBPE 🇪🇺 (@stephenemoss) March 13, 2020

Lots of ideas in this tweet and replies.

We’ve been advised to prep our labs for potential #COVID19 shutdown. We've discussed:
1. Flexibility to work from home
2. Avoid starting long-term studies
3. Freeze down cells
4. Reduce mouse cage numbers
5. Be prepared to separate breeding pairs

Other ideas? #InThisTogether

— Joy Wu, MD, PhD (@JoyYWu) March 9, 2020

We are also discussing what we need to do….Stock up on cell media, make sure liquid nitrogen topped up, trying to coordinate cell culture access to maintain some of our oldest iPSC-neurons (~1y) via minimal access, freeze down iPSC that need daily feeding…. https://t.co/dYNYqm8tIl

— Prof Selina Wray (@SelinaWray) March 11, 2020

The Yaniv lab is Staying positive

Here’s the @yaniv_lab keeping up the good spirit! With one student (corona positive 😱😱) interviewed by the Israeli news, and myself on quarantine (😔😔😔) after returning from @GordonConf lymphatics, we try our best to stay healthy and happy! pic.twitter.com/f96weOshCt

— 🎗️Karina Yaniv🎗️ (@KarinaYaniv) March 12, 2020

The Gallego lab is using the lockdown as a chance to become better, computationally speaking

We changed pipettes by computers! We didn't plan working from home… but this is a fantastic opportunity to strengthen our computational power. We'll be back in a few weeks, and we'll be better in
#bioinformatics #Imageanalysis #modeling #Python pic.twitter.com/VA4V2Y8Rv8

— Gallego Lab (@GallegoLab) March 12, 2020

48 hours to shut down the Bardelli lab in Italy

9pm Italy, we were given 48hrs to shut down the @BardelliLab, I wanted to be last to leave, and now is time to go. I said goodbye to my post docs, PhDs, techs, we are all part of a worldwide family. I will miss my team and look fwd to continue the fight against #cancer from home! pic.twitter.com/y4MeZ3Ztsc

— Alberto Bardelli (@Albert0Bardelli) March 11, 2020

And, please don’t do this, PIs!

Already hearing stories of postdocs being explicitly instructed by faculty that they are NOT to work from home, but must be in lab as usual. If you are a PI, PLEASE don't do this. If you hear of others doing it please exercise what powers of peer pressure you have.

— Dr. Sam Dundon (@serdundon) March 11, 2020

A thread on zebrafish emergency preparedness

Seems like C. elegans researchers are a little less worried!

Never been more thankful for C. elegans dauers than in this era of campus shutdowns. #ILoveWorms

— Piali Sengupta (@SenguptaLab) March 11, 2020

To fight social isolation, why not set up a virutal coffee break?

and engage with one another, with no agenda other than to connect and hopefully avoid some of feelings of isolation that can occur when working alone. I have instituted the same thing with my lab now, and hopefully it will help us all get through these unprecedented times /fin

— Gavin Sherlock (@gsherloc) March 12, 2020

Or a virtual happy hour?

https://twitter.com/JShendure/status/1237640592147931136

Keep educating: a thread on how to use Zoom to lecture from home

A perspective on online learning from the Open University

Online courses could help fill your days

Since I won't be leaving the house much in the coming weeks, I am particularly looking forward to participating in this free online course "Teaching Biology: Inspiring Students with Plant Science" Who wants to join me? Starts Monday.https://t.co/u17eX0J5ge

— mary williams (@PlantTeaching) March 12, 2020

Cancelled conferences? Why not share your talk and poster online:

Dear early career researchers,

If you conference was cancelled, share your poster or talk online & use the conference hashtag.

There is a good chance that you’ll have dozens—if not hundreds—of people who will check it out.

This is far more efficient way to share your work. https://t.co/gSn7mfUrXU

— Jay Van Bavel, PhD (@jayvanbavel) March 10, 2020

Indeed we are planning to help with this for the BSDB Spring meeting, which would have started on Sunday. More info here:

eBSDB/GenSoc 2020 plans

Virtual seminar series – more ideas in the replies

If things really shut down. Who wants to start a virtual seminar series with me. Or something.

— Tom Kash (@superkash) March 12, 2020

Help for conference organisers from OSF

Conference organizers, if you would like to promote sharing of conference presentations and posters amid COVID-19 cancellations, the free OSF Meetings service is available for authors to easily submit and share their work. Sign-up here: https://t.co/p2zXo1sy3k. https://t.co/rieeguq7tX

— Brian Nosek (@briannosek@nerdculture.de) (@BrianNosek) March 10, 2020

Please let us know if you find any other useful links.

(3 votes)

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Here at the Node and Development, the BSDB Spring meeting is always the first thing to go into our conference calendar, as an institution for the UK developmental biology community. The 2020 meeting, co-organised with the Genetics Society and due to start on Sunday, has just been cancelled due to concerns about spread of Covid-19 (more info will be available soon and we’ll share it here). It joins other recently cancelled developmental biology conferences (such as those in EMBL Heidelberg and Keystone). It seems to us to have been an inevitable decision, if a sad one, and we look forward to the next time a few hundred developmental biologists get together in the bar in Warwick!

Some photos of the last two meetings, ripped from Twitter:

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The fellowship is a part of a 5-year project “ Co-evolution of metacaspase structure and biological function in Arabidopsis”, which aims to advance our mechanistic understanding of metacaspase family proteases in close cooperation between five research groups located in Uppsala BioCenter at SLU, Umeå SLU and Umeå University. The successful candidate for this fellowship will join the group of Hannele Tuominen at UPSC in Umeå, Sweden.

Umeå Plant Science Centre (UPSC) is a research centre in Umeå, Sweden (www.upsc.se) where research of both basic and strategic importance is conducted. The research at UPSC is carried out on all organization levels of the plant with a common goal to understand the plant as a complex organism in dynamic interaction with its environment.

Previous studies carried out by the host and other laboratories have linked metacaspases to regulation of aging and cell death in diverse organisms (Escamez et al., 2020). The Arabidopsis thaliana Metacaspase9 (MC9) is required for the rapid autolysis of the xylem vessel elements (Bollhöner et al., 2013), but the underlying mechanism as well as the proteolytic substrates of MC9 remain poorly understood. The main purpose of this project is to study MC9-mediated cleavage of target proteins which results in production of biologically active peptides, including the previously identified Bia and Kratos peptides (Escamez et al., 2019, J Exp Bot. 70:2199-2210). The function of the peptides is investigated in vascular differentiation of Arabidopsis using genetic, proteomic and biochemical methods. Other aspects of the project can be developed according to the interests of the candidate.

• Bollhöner B, Zhang B, Stael S, Denancé N, Overmyer K, Goffner D, van Breusegem F and Tuominen H 2013. Post mortem function of AtMC9 in xylem vessel elements. New Phytologist 200:498-510.
• Escamez S, Stael S, Vainonen J, Willems P, Jin H, Kimura S, Van Breusegem F, Gevaert K_, Wrzaczek M, and Tuominen H. 2019. Extracellular peptide Kratos restricts cell death during vascular development and stress in Arabidopsis. Journal of Experimental botany 70: 2199–2210.
• Escamez S, André D, Sztojka B, Bollhöner B, Hall H, Berthet B, Voss U, Lers A, Maizel A, Andersson M, Bennett M, Tuominen H. 2020. Cell death in cells overlying lateral root primordia contributes to organ growth in Arabidopsis. Current Biology 30: 1–10.

We are looking for a highly motivated plant biologist with a keen interest in understanding mechanisms and role of proteolysis in a developmental context. Successful candidates are expected to have a PhD degree, experience in cell and molecular biology and genetics, and a proven research track record.

A stipend is granted for 2 years starting in August 1, 2020 or by agreement. The tax-free stipend is financed by the Wallenberg foundation and amounts to 288 000 SEK per year. The fellowship can be prolonged by a two-year University employment after positive evaluation. The project involves visits to collaborating laboratories.

Please send you application, including a personal letter, CV, and contact information of three references by e-mail to Hannele.tuominen@slu.se latest 30 April 2020.

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DanStem
The Novo Nordisk Foundation Center for Stem Cell Biology (DanStem) addresses fundamental research questions in stem cell and developmental biology and seeks to develop translational activities based on this fundamental discovery science, producing new therapeutic strategies for chronic diseases. Current focus at DanStem is predominantly on fundamental research at the highest level, and the Center also offers investigators the opportunity to develop their work in the translational arena, providing opportunities for strategic development aiming at clinical application. DanStem is a vibrant, internationally diverse and ambitious research center with state-of-the-art facilities located at the Faculty of Health and Medical Sciences, University of Copenhagen. The setting is ideally situated for seamless collaboration and exchange with other centers and departments of the Faculty and the surrounding hospitals
DanStem is dedicated to promoting research in stem cell and developmental biology within Denmark and throughout Europe. A part of this commitment involves the training og the next generation of stem cell scientist. To this end DanStem engages in pre-graduate training, operates a four-year PhD program, offers a broad spectrum of post-graduate teaching and a number of out-reach activities. DanStem also engages in active post-doctoral t5raining and mentorship programs. Together with its large post-graduate and post-doctoral population, DanStem represents a major European hub for training in contemporary stem cell biology.

Learn more about DanStem at https://danstem.ku.dk/.

DanStem is a part of the NNF Center Cluster, that also contains the Centers for Protein Research (CPR), Basic Metabolic Research (CBMR) and Biosustainability. Three of these centers are located in the Faculty of Health and Medical Science at the University of Copenhagen. DanStem is situated in the Panum building along with CPR, with whom it shares research technology platforms. DanStem is also on the same campus as CBMR and a number of other relevant departments in biomedical sciences. A short walking distance from DanStem is the Biotech Research and Innovation Center (BRIC), a high-profile, vibrant and international center for cancer and epigenetics research at the Faculty, where some of the DanStem research programs are based.  As a result of DanStem’s proximity, there is ample opportunity for educational and research collaborations. DanStem is well integrated into European science and recognized internationally as a key player in stem cell research.

DanStem is a highly international and rewarding workplace with a staff of 250, placing high value on diversity and synergistic approaches to solving the challenges of developmental and stem cell biology. As DanStem has evolved in the last ten years its research approaches have become increasingly interdisciplinary and quantitative. Its location next to the Niels Bohr Institute and in close proximity to Denmark’s leading technical university (Danish Technical University) has helped enable this transition. Importantly, while DanStem will continue solving fundamental questions in stem cell biology, the future will emphasize and strengthen translational stem cell-based applications. This will be enabled through the Faculty’s strong collaboration with the hospitals.

DanStem Executive Directorship
Qualified Executive Director candidates will be visionary scientific leaders of international stature with a strong track record of innovative research in developmental and stem cell biology. They will also have the vision to identify and support new translational programs aiming at clinical application. They are expected to have a strong track record of collaboration and a history in building interdisciplinary academic research in a collaborative environment. The Executive Director will lead the overall research directions at the Center and promote the research carried out by DanStem’s faculty. A management team and Scientific Advisory Board support the Executive Director.

Expectations
The Executive Director will:

• Be responsible for development of the Center, including producing and implementing a vision for future scientific growth as well as the recruitment of a new generation of outstanding and highly interactive researchers
• Lead her/his own research group
• Develop new strategic initiatives and support existing and future translational programs
• Participate in fostering new collaborations
• Work closely with key scientific and administrative staff to develop a comprehensive research strategy and guide the future direction of DanStem’s research portfolio
• Collaborate on cross center initiatives with CPR and CBMR, as well as other national and international research centers
• Report to the Dean of the Faculty of Health and Medical Sciences and work closely with Dean’s office in a variety of joint efforts including educational activities
• Lead the writing of the strategic application to NNF for funding of the renewal period (8 years).

Qualifications and experience
The successful candidate will:

• Hold an appropriate doctoral degree
• Have an outstanding record of scientific discovery and accomplishment, including a track record of substantial external competitive funding and proven success in collaborations
• Present a clear vision of future directions in areas related to developmental and stem cell biology, including how fundamental science can provide technological innovation and clinical translation
• Demonstrate excellent interpersonal and leadership skills, especially with regard to successful leadership of international and diverse teams
• Proven management skills
• Show a commitment to foster and promote excellence in scientific research and education

Inquiries
For informal inquiries and more information about position, you are welcome to contact Dean Ulla Wewer (dekan@sund.ku.dk),  Professor Tor Henrik Semb (semb@sund.ku.dk) or Perrett Laver (see contact information below).

Submitting letter of interest
Perrett Laver is assisting the search committee with the recruitment process. Perrett Laver may also be contacted for informal inquiries and questions on Jack.Bircher@perrettlaver.com or +44 (0)20 7340 6275. Further information, including details on how to apply, can be downloaded at https://candidates.perrettlaver.com/vacancies/ quoting reference 4558.

Please include the following documents, when submitting your letter of interest:

• Your curriculum vitae, detailing employment history, and academic and professional qualifications (max. 4 pages including bio sketch)
• A description of your vision for the future of developmental and stem cell biology and how you believe DanStem could contribute to this  (max. 5 pages)
• A list of not more than 10 selected publications
• A link or reference to a complete list of publications (e.g. ORCID).

Deadline for submitting letters of interest: April 15th 2020 at 23:59 CET.

For further information about

• DanStem, please visit https://danstem.ku.dk
• Copenhagen Bioscience Cluster, a Novo Nordisk Foundation initiative, please visit https://cph–bioscience.com/en/
• University of Copenhagen, Faculty of Health and Medical Sciences, please visit https://healthsciences.ku.dk

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

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The Danish Stem Cell Center (DanStem) at Faculty of Health & Medical Sciences at the University of Copenhagen is looking for a Postdoctoral candidate to join the Żylicz group starting July 2020 or upon agreement with the chosen candidate.

A postdoctoral position is available in the group of Jan Żylicz at DanStem. The team studies fundamental mechanisms of early mouse development and stem cell biology. The Żylicz group wants to understand how metabolic and epigenetic mechanisms cooperate to regulate transcription during early development. In particular the team is interested in how metabolism regulates histone modifiers, and how these in turn affect lineage choice and embryo growth at around the time of implantation. To achieve this, the group utilizes both in vivo mouse models as well as in vitro stem cell culture systems and state-of the-art ultrasensitive transcriptomic, epigenomic and metabolomic techniques. This research project will employ high-throughput screening methods to uncover metallic regulators underpinning chromatin states of mouse stem cell models. Starting date for this position is the 1 June 2020, or upon agreement with the chosen candidate.

Job description:
We are seeking a highly motivated and ambitious post-doctoral candidate with a strong background in either stem cell and developmental biology and/or metabolomic research. The candidate implement high-throughput screening techniques to identify key metabolic players regulating chromatin states in vitro and in vivo. By using functional assays in combination with live imaging and ultra-sensitive chromatin mapping and metabolomic techniques the candidate will get at the underlying principles of epi-metabolic regulation.

About DanStem
The Novo Nordisk Foundation Center for Stem Cell Biology – DanStem – addresses basic research questions in stem cell and developmental biology and translates results from basic research into new strategies and targets for the development of new therapies for diabetes and cancer. DanStem was established as a result of a series of international recruitments coupled with internationally recognized research groups focused on insulin producing beta cells and cancer research already located at the University of Copenhagen.

Qualifications:

• Candidates must hold a PhD degree in cell/developmental/stem cell biology/metabolomics or similar, with a track-record of successful scientific work.
• Candidates should have a strong background in mouse genetics, cell biology and/or live cell imaging. Alternatively candidates with a background in metabolomics applied to animal models are also encouraged to apply.
• Previous experience in metabolomics, bioinformatics, next-generation sequencing, mouse embryology and/or stem cell culture are considered an advantage.
• Good English communication skills, both oral and written, are prerequisite for the successful candidate.

Terms of salary, work, and employment :
The employment is planned to start 1 July 2020 or upon agreement with the chosen candidate. The employment is initially for 2 years. The terms of employment are set according to the Agreement between the Ministry of Finance and The Danish Confederation of Professional Associations or other relevant professional organization. The position will be at the level of postdoctoral fellow and the basic salary according to seniority. Currently, the salary starts at 34.360 DKK/approx. 4,.590 Euro (October 2019-level). A supplement could be negotiated, dependent on the candidate ́s experiences and qualifications. In addition a monthly contribution of 17.1% of the salary is paid into a pension fund.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark the last 10 years.
The position is covered by the “Memorandum on Job Structure for Academic Staff at the Universities” of December 11, 2019.

Questions:
For further information contact Associate Professor Jan Żylicz, jan.zylicz@sund.ku.dk.

Foreign applicants may find the following links useful: www.ism.ku.dk (International Staff Mobility) and www.workingconditions.ku.dk.

How to apply
The application, in English, must be submitted electronically by clicking APPLY below.

The application must include:

1. Motivation letter
2. Curriculum vitae incl. education, experience, previous employments, language skills and other relevant skills
3. List of two references (full address, incl. email and phone number)
4. List of publications
5. Copy of diplomas/degree certificate(s)

Application deadline: April 14, 2020

The University of Copenhagen wishes to reflect the diversity of society and welcomes applications from all qualified candidates regardless of personal background.

Only applications received in time and consisting of the above listed documents will be considered.

Applications and/or any material received after deadline will not be taken into consideration.

The application will be assessed according to the Ministerial Order no. 284 of 25 April 2008 on the Appointment of Academic Staff at Universities.

Assessment procedure
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the Appointments Committee. All applicants are then immediately notified whether their application has been passed for assessment by an expert assessment committee. Selected applicants are notified of the composition of the committee and each applicant has the opportunity to comment on the part of the assessment that relates to the applicant him/herself.

You can read about the recruitment process at http://employment.ku.dk/faculty/recruitment-process/

Interviews are expected to be held in weeks 20

University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of age, disability, gender, nationality, race, religion or sexual orientation. Appointment will be based on merit alone.

 APPLY ONLINE

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