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Wellcome Trust Independent Senior Research Fellow at Warwick Medical School

Posted by , on 27 January 2016

Closing Date: 15 March 2021

http://www.jobs.ac.uk/job/AUC078/wellcome-trust-independent-senior-research-fellow-75344-016/

The University of Warwick has initiated a Wellcome-Trust funded research programme in “Quantitative Biomedicine” to bridge physical / mathematical sciences and biomedicine. The programme is of a cross-campus nature with strong participation from the Division of Biomedical Cell Biology and the Warwick Systems Biology Centre.

We are seeking early career researchers who are no more than 4 years from obtaining a Doctoral degree with the potential to lead a strong independent research programme. The candidates will be selected based on their track record in innovative research and on the strength of the research proposal. Importantly, the proposals should make clear how the project benefits from quantitative methodologies. The proposed research programme should bring together physical and mathematical sciences and biomedical sciences (including cell and developmental biology, neurobiology, immunology, microbiology and infection). Identified candidates will be provided salary, laboratory space, running costs and part-time technical support for three years. The successful candidates will be expected to win externally funded fellowships within the contract period and will be mentored in preparing such applications.

Interested candidates should submit their CV, a two-page research proposal, and the names and addresses of three referees who are able to comment on the candidates past research work as well as the readiness of the candidate to embark on an independent career in research.

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Eco Evo Devo Postgraduate Summer School

Posted by , on 27 January 2016

Dear Colleagues,

We are delighted to offer our 3rd Eco-Evo-Devo Postgraduate Summer School from August 8th to 12th 2016 at Oxford Brookes University.

For full details please see the Summer School website:

http://bms.brookes.ac.uk/ceec/courses/eco-evo-devo-summer

Alistair McGregor.

 

poster_SummerSchool_new

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Categories: Education, Events, News

4-year PhD position available at the Sars Centre in Bergen/Norway.

Posted by , on 27 January 2016

Closing Date: 15 March 2021

A 4-year PhD position is available in the Steinmetz lab to study the role of nutrients and feeding in gamete growth and maturation in cnidarians.

Please find more details on the position and the application here:

http://tinyurl.com/h7y4h6y

More info on the lab:

http://www.sars.no/research/SteinmetzGrp.php

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PhD position available to study arachnid evolution and development

Posted by , on 26 January 2016

Closing Date: 15 March 2021

 

PhD position available in the McGregor lab (http://mcgregor-evo-devo-lab.net/McGregor_lab/home.html) to investigate the role of gene duplication and divergence during the evolution of spiders, scorpions and other arachnids:

http://master.findaphd.com/search/ProjectDetails.aspx?PJID=72054

 

 

 

 

 

 

 

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Cosy Science talk- Repairing a broken heart: lessons from evolution and development

Posted by , on 26 January 2016

moon

Cosy Science is an informal pub gathering where scientists talk about their research over a pint of beer (or glass of wine!) with anyone who is interested in listening. It is mostly a monthly event, taking place at The Cittie of Yorke pub in London, and everyone is welcome!

 

Brian BlackAs you may know, The Company of Biologists runs a series of workshops for scientists, and we collaborate with Cosy Science to bring some of the exciting research discussed at the workshops to the general public. Our next workshop will focus on transdifferentiation and tissue plasticity in cardiavascular rejuvenation, and one of the organisers, Dr Brian Black (Cardiovascular Research Institute at the University of California, San Francisco) will be joining Cosy Science on Wednesday the 10th of February to bring developmental biology to the pub! Brian will give a short talk about what cardiac development in utero and cardiac regeneration in fish and salamanders may be able to teach us about regenerating cardiac muscle after a heart attack. After a short break to refill, the floor will be open for questions and friendly discussion. So if you’re in the area, bring along that friend who always wanted to know what developmental biology is all about, and enjoy an evening of pub science sponsored by The Company of Biologists!

 

Find out more information at the Cosy Science website.

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Categories: Events, News, Outreach

Meeting reporter wanted for Germline Stem Cells Conference in San Fran!

Posted by , on 26 January 2016

Germline_Homepage_Slider

 

Germline Stem Cells Conference

June 19-21, 2016 – San Francisco, California

Website: www.abcam.com/germlinestemcells

Germline stem cells represent a uniquely critical type of stem cell that is essential for fertility and propagation of the species. The topic of germline stem cells has become an active area of study both in mammalian systems and in non-mammalian model systems including flies, worms and fish.

Free registration for grabs! Abcam and the Node are looking for an official meeting reporter to attend this meeting. The Reporter will be responsible for providing regular updates of interesting talks/discussions for twitter/tweets (by Abcam), plus a meeting report of their experience and the sights and sounds of the meeting (for publishing on The Node and Abcam website).

To apply to be the meeting reporter, please send a short paragraph (max. 200 words) to events@abcam.com, letting us know why you are the best scientist for the job! Application deadline: April 15, 2016. The winner will receive free registration to the meeting (travel and accommodation not included).
Meeting information:

Organizers: John McCarrey (University of Texas at San Antonio) and Jon Oatley (Washing State University)

Keynote Speakers: D.G. (Dirk) de Rooij (Utrecht University) Azim Surani (The Gurdon Institute)

Confirmed speakers: Norman Arnheim, Brad Cairns, Amander Clark, Margaret Fuller, Christopher Geyer, Brian Hermann, Patricia Hunt, Diana Laird, Erika Matunis, John McCarrey, Jon Oatley, Susan Strome, Miles Wilkinson, and Kyle Orwig.

 

Call for abstracts: Abstracts are invited for short talks or poster presentations and can be submitted during registration. Those selected will be notified after the April 18 deadline.

 

Check out the article written by last years official meeting reporter winner here!

 

 

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Categories: Events, News

Peter Lawrence

Posted by , on 26 January 2016

What ho nodites,

I am putting here a link to my latest polemic on the issues discussed in the interview and some others. Of course being carefully written it is a little more accurate and pointed and widely ranging than the verbatim interview.

There might be a way of reading it gratis if you drop me a line, pal38@cam.ac.uk

 

here is the link

 

http://www.sciencedirect.com/science/bookseries/aip/00702153

 

Peter

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Categories: Discussion

From our sister journals- January 2016

Posted by , on 26 January 2016

Here is some developmental biology-related content from other journals published by The Company of Biologists.

 

CoB_DisModMech_AW_RGB

 

Characterisation of Slc9a6 knockout heterozygous female mice

DMM Jan2016Mutations in SLC9A6 are responsible for X-linked Christianson syndrome, a neurodevelopmental disease. Sikora and colleagues demonstrate that female mice heterozygous for a Slc9a6 knockout present mosaic neuropathology and similar but milder behavioural traits to those of affected males. Read the paper here. [OPEN ACCESS]

 

 

 

Journal typography

 

Sp5 emerges as an important component in mESC naïve pluripotency

JCSJan2016_1Sp5 has been identified as an effector of both Wnt/β-catenin and leukemia inhibitory factor (LIF)/Stat3 pluripotency signaling, and its forced expression produces effects of both pathways in mESC pluripotency. Furthermore, Sp5 can convert mouse epiblast stem cells into mESCs. Read the paper here. [OPEN ACCESS]

 

 

FGF signalling on E-Cadherin impacts primordial germ cell motility

JCSJan2016_2In this paper, Parès and Ricardo describe how fibroblast growth factor (FGF) signaling modulates zygotic E-cadherin distribution to maintain posterior midgut epithelial 3D architecture, impacting on primordial germ cell motility during the early embryonic development of Drosophila. Read the paper here.

 

 

Targets identified for NF-κB-modulated microRNAs that inhibit myoblast proliferation

JCSJan2016_3Wei and colleagues show that miR-195 and miR-497 target lgf1rlnsrCcnd2 and Ccne1 and inhibit proliferation in C2C12 cells. They also show that these microRNAs are negatively regulated by nuclear factor κB, illustrating an important signalling pathway in myogenesis. Read the paper here.

 

 

Reciprocal regulation of alternative lineages by Rgs18 and its transcriptional repressor Gfi1b

JCSJan2016_4Sengupta and colleagues describe how Rgs18, a GTPase-activating protein, and its transcriptional repressor Gfi1b reciprocally regulate the lineage segregation between the megakaryocytic and the erythroid lineage through the downstream effects on the antagonistic transcription factors Fli1 and Klf1. Read the paper here.

 

 

 

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Categories: Research

New 3D anatomy viewer available at eMouseAtlas

Posted by , on 26 January 2016

A new 3D viewer that allows interactive visualisation of mouse embryo anatomy is now available from the eMouseAtlas website (www.emouseatlas.org/). A slice viewer allows visualisation of anatomy on arbitrary section through mouse embryos – much like a virtual microtome – whilst a 3D anatomy pop-up window allows users to visualise the delineated anatomical components in an interactive 3D-context as either a wireframe or surface-rendered model. There is the additional option to change colour for selected anatomical components in both the slice viewer and the 3D anatomy pop-up window.

 

The new viewer uses IIP3D and WebGL technology to allow interactive exploration of 3D anatomy in a HTML5-compatible and WebGL-enabled web-browser and without the need for data download.

 

3D anatomy
The new 3D anatomy viewer enables visualisation of mouse embryo anatomy in a web browser.

 

eMouseAtlas continues to develop tools and resources that enable high-end visualisation of embryo data. The anatomy is delineated to a very high standard and can be used for both research and for learning. There are future plans to explore use of this 3D viewer in web-based visualisation of 3D gene expression and phenotype data.

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Categories: Images, Resources

Postdoctoral Research Scientist position in Cardiac Developmental Biology – University of Oxford

Posted by , on 25 January 2016

Closing Date: 15 March 2021

Applications are invited for a Postdoctoral Research Scientist to join Professor Mathilda Mommersteeg’s laboratory to work on a project focussed on characterising the role of the Slit-Robo signalling pathway in cardiac innervation patterning. The post would be ideally suited to a postdoctoral scientist with experience in working with mouse models and background expertise in mammalian heart development or developmental neuroscience. More information through the link.

 

You will use conditional knock-out approaches to analyse the role of the pathway in cardiac innervation guidance, both during development and in disease. The techniques used will include immunohistochemistry, use of Amira software for 3D reconstructions of innervation, in vitro axon guidance assays and telemetry ECG analysis.

 

You must hold, or be near completion of, a PhD or equivalent in a relevant area of research and have a background in mammalian developmental biology and/or cardiovascular sciences and/or neuroscience.

 

You will be based in the Sherrington Building in the Department of Physiology, Anatomy and Genetics at the University of Oxford.

 

The position is funded by the British Heart Foundation for up to 2.5 years.

The closing date for applications is 12.00 noon on Monday 8 February 2016.

https://www.recruit.ox.ac.uk/pls/hrisliverecruit/erq_jobspec_version_4.jobspec?p_id=121602

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