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Job opportunity: Reviews Editor on Development

Posted by , on 5 March 2025

As well as looking for the next Executive Editor for Development, we are also recruiting a Reviews Editor on the journal. If you love developmental biology but don’t want to be ‘doing’ it any more, this is a great opportunity to stay connected to the field and the community and to help shape the content of the journal. You’ll commission and edit review-type articles and perspectives, conduct interviews, write research highlights, travel to conferences and contribute to the strategic development of the journal. As a small publishing company, you’ll get great exposure to all aspects of the business – both the publishing and the charitable side – and you’ll also get to work for an organisation that really believes in supporting the academic community. All the details can be found in the job advert on our website.

You don’t need to have prior editorial experience (though obviously we’d be delighted to receive applications from people who do); what you do need are research experience and a broad interest in the field, excellent communication skills, and a willingness to learn! If this sounds like something you might be interested in, please feel free to get in touch with informal questions, or just apply directly (instructions in the job ad). The deadline for applications is 31 March 2025.

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February in preprints

Posted by , on 4 March 2025

Welcome to our monthly trawl for developmental and stem cell biology (and related) preprints.

The preprints this month are hosted on bioRxiv – use these links below to get to the section you want:

Developmental biology

Cell Biology

Modelling

Tools & Resources

Spotted a preprint in this list that you love? If you’re keen to gain some science writing experience and be part of a friendly, diverse and international community, consider joining preLights and writing a preprint highlight article.

Developmental biology

| Patterning & signalling

Mac/Lac-tosylceramide regulates intestinal homeostasis and secretory cell fate commitment by facilitating Notch signaling

Kebei Tang, Xuewen Li, Jiulong Hu, Jingyuan Shi, Yumei Li, Yansu Chen, Chang Yin, Fengchao Wang, Rongwen Xi

Genetic evidence: zebrafish hoxba and hoxbb clusters are essential for the anterior-posterior positioning of pectoral fins

Morimichi Kikuchi, Renka Fujii, Daiki Kobayashi, Yuki Kawabe, Haruna Kanno, Sohju Toyama, Farah Tawakkal, Kazuya Yamada, Akinori Kawamura

Geometry-driven asymmetric cell divisions pattern cell cycles and zygotic genome activation in the zebrafish embryo

Nikhil Mishra, Yuting I. Li, Edouard Hannezo, Carl-Philipp Heisenberg

Insect wings arose with a genetic circuit that extends the useful range of a BMP morphogen

Anqi Huang, Luca Cocconi, Ben Nicholls-Mindlin, Cyrille Alexandre, Guillaume Salbreux, Jean-Paul Vincent

Divergent Hox cluster collinearity in horned beetles reveals adult head patterning function of labial

Erica M. Nadolski, Isabel G. Manley, Sukhmani Gill, Armin P. Moczek

Geometric, cell cycle and maternal-to-zygotic transition-associated YAP dynamics during preimplantation embryo development

Madeleine Chalifoux, Maria Avdeeva, Eszter Posfai

From Chalifoux et al. This image is made available under a CC-BY-NC 4.0 International license.

Measuring morphogen transport over multiple spatial scales in live zebrafish embryos

Ashwin V. S. Nelanuthala, Bitan Saha, Jagadish Sankaran, Tom J. Carney, Karuna Sampath, Thorsten Wohland

Anti-resonance in developmental signaling regulates cell fate decisions

Samuel J. Rosen, Olivier Witteveen, Naomi Baxter, Ryan S. Lach, Marianne Bauer, Maxwell Z. Wilson

CHD3 regulates BMP signalling response during cranial neural crest cell specification

Zoe H. Mitchell, Joery den Hoed, Willemijn Claassen, Martina Demurtas, Laura Deelen, Philippe M. Campeau, Karen Liu, Simon E. Fisher, Marco Trizzino

Shared Lineage, Distinct Outcomes: Yap and Taz Loss Differentially Impact Schwann and Olfactory Ensheathing Cell Development Without Disrupting GnRH-1 Migration

Ed Zandro M. Taroc, Enrico Amato Jr., Alexis Semon, Nikki Dolphin, Briane Beck, Sophie Belin, Yannick Poitelon, Paolo E. Forni

Bdnf-Ntrk2 Signaling Promotes but is not Essential for Spinal Cord Myelination in Larval Zebrafish

Kristen Russell, Christina A. Kearns, Macie B. Walker, Christopher S. Knoeckel, Angeles B. Ribera, Caleb A. Doll, Bruce Appel

| Morphogenesis & mechanics

Endoderm differentiates into a transient epidermis in the mouse perineum

Christine E. Larkins, Daniel M. Grunberg, Gabriel M. Daniels, Erik J. Feldtmann, Martin J. Cohn

Molecular insights into electroreceptor ribbon synapses from differential gene expression in sturgeon lateral line organs

Alexander S. Campbell, Martin Minařík, David Buckley, Tanmay Anand, David Gela, Martin Pšenička, Clare V. H. Baker

Myelination across cortical hierarchies and depths in humans and macaques

Monami Nishio, Xingyu Liu, Allyson P. Mackey, Michael J. Arcaro

Defects in nephrogenesis result in an expansion of the Foxd1+ stromal progenitor population

Michael G. Michalopulos, Yan Liu, Dinesh Ravindra Raju, John T. Lafin, Yanru Ma, Dhruv Gaur, Sadiksha Khadka, Chao Xing, Andrew P. McMahon, Thomas J. Carroll, Keri A. Drake

Analysis of molecular and cellular bases of honey bee mushroom body development

Shuichi Kamata, Takeo Kubo, Hiroki Kohno

Cross-Species Biomechanical Determinants of Shape Diversity

Richard Bailleul, Nicolas Cuny, Diana Khoromoskaia, Soham Basu, Giulia Bergamini, Paolo Cucurachi, Sebastian Rupp, Annika Guse, Camille Curantz, Natalie Swinhoe, Phillip Cleves, Jamie Craggs, Sosuke Fujita, Yu-ichiro Nakajima, Petrus J. Steenbergen, Alba Diz-Muñoz, Guillaume Salbreux, Aissam Ikmi

From Bailleul et al. This image is made available under a CC-BY 4.0 International license.

Testosterone exposure during fetal masculinization programming window determines the kidney size in adult mice

Arttu Junnila, Kalle T. Rytkönen, Guillermo Martinez-Nieto, Mats Perk, Hao Li, Jenni Airaksinen, Ida Hyötyläinen, Oliver Mehtovuori, Asta Laiho, Claes Ohlsson, Laura L. Elo, Satu Kuure, Matti Poutanen, Petra Sipilä

Mouse scalp development requires Rac1 and SRF for the maintenance of mechanosensing mesenchyme

Bharath H. Rathnakar, Alex Rackley, Hae Ryong Kwon, William L. Berry, Lorin E. Olson

A prevalent Krt8-to-Krt5 cellular state transition in skin is co-opted by p63 for enamel organ development

Qinghuang Tang, Jung-Mi Lee, Liwen Li, Chunmiao Cai, Hunmin Jung, Hyuk-Jae Edward Kwon

Development of the zebrafish anterior lateral line system is influenced by underlying cranial neural crest

Vishruth Venkataraman, Noel H. McGrory, Theresa J. Christiansen, Joaquin Navajas Acedo, Michael I. Coates, Victoria E. Prince

Additive effects on craniofacial development upon conditional ablation of PDGFRα and SHP2 in the mouse neural crest lineage

Daniel Fuhr, Jessica Johnston, Elliott P. Brooks, Katherine A. Fantauzzo

Keratins coordinate tissue spreading by balancing spreading forces with tissue material properties

Suyash Naik, Yann-Edwin Keta, Kornelija Pranjic-Ferscha, Édouard Hannezo, Silke Henkes, Carl-Philipp Heisenberg

mTOR regulates Wnt signaling to promote tension-mediated lens vesicle closure

Qian Wang, Hao Wu, Yingyu Mao, Alyssa Chow, Michael Bouaziz, Yihua Wu, Xin Zhang

A myofilament lattice model of Drosophila flight muscle sarcomeres based on multiscale morphometric analysis during development

Péter Görög, Tibor Novák, Tamás F. Polgár, Péter Bíró, Adél Gutheil, Csaba Kozma, Tamás Gajdos, Krisztina Tóth, Alexandra Tóth, Miklós Erdélyi, József Mihály, Szilárd Szikora

Altered pseudostratified epithelial development of the lateral ventricle choroid plexus in Mllt11 mutants

Sam Moore, Danielle Stanton-Turcotte, Angelo Iulianella

Noncanonical Wnt/Ror2 Signaling Regulates Basal Cell Fidelity and Branching Morphogenesis in the Mammary Gland

Hongjiang Si, Erika Mendoza Mendoza, Madelyn Esquivel, Chad J. Creighton, Jianming Xu, Kevin Roarty

From Si et al. This image is made available under a CC-BY 4.0 International license.

| Genes & genomes

Active DNA demethylation is upstream of rod-photoreceptor fate determination and required for retinal development

Ismael Hernández-Núñez, Alaina Urman, Xiaodong Zhang, William Jacobs, Christy Hoffman, Sohini Rebba, Ellen G Harding, Qiang Li, Fengbiao Mao, Andi K Cani, Shiming Chen, Meelad M Dawlaty, Rajesh C Rao, Philip A Ruzycki, John R Edwards, Brian S Clark

Mismatch repair and homologous recombination are yin-yang partners in hybrid zygote meiosis

Chi-Ning Chuang, Ya-Ling Hung, Hong-Xiang Kim, Jhong-Syuan Yao, Hou-Cheng Liu, Sheng-Yuan Chen, Lavernchy Jovanska, Yi-Ping Hsueh, Ruey-Shyang Chen, Ting-Fang Wang

Spatially regulated mRNA decay sharpens expression patterns in the Drosophila embryo

Jennifer C. Love, Lauren Forbes Beadle, Catherine Sutcliffe, Magnus Rattray, Hilary L. Ashe

Differential Roles of Broadly Expressed Transcription Factors in Early Cardiac Cell Specification

Shiva Abbasi, Evangelia Chrysostomou, Georgios Tegousis, Oscar Villasana Espinosa, Rie Conley, Theodora Koromila

MYRF is Essential in Mesothelial Cells to Promote Lung Development and Maturation

Gidsela Luna, Jamie Verheyden, Chunting Tan, Estelle Kim, Michelle Hwa, Jugraj Sahi, Yufeng Shen, Wendy Chung, David McCulley, Xin Sun

Feed-forward loops by NR5A2 ensure robust gene activation during pre-implantation development

Wataru Kobayashi, Siwat Ruangroengkulrith, Eda Nur Arslantas, Adarsh Mohanan, Kikue Tachibana

The mex-3 3’ untranslated region is essential for reproduction during temperature stress

Hannah E. Brown, Haik V. Varderesian, Sara A. Keane, Sean P. Ryder

Dora, a key component of target-directed miRNA degradation, is essential for local genomic amplification in Drosophila ovarian follicle cells

Natalia Akulenko, Oxana Olenkina, Elena Mikhaleva, Sofya Marfina, Anastasia Krylova, Stepan Toshchakov, Sergei Ryazansky

Single-Cell Roadmap of Early Hemato-Endothelial Development: Functions of Atf3, Zfp711 and Bcl6b

Ridvan Cetin, Giulia Picco, Jente van Staalduinen, Eric Bindels, Remco Hoogenboezem, Gregory van Beek, Mathijs A Sanders, Yaren Fidan, Ahmet Korkmaz, Joost Gribnau, Jeffrey van Haren, Danny Huylebroeck, Eskeatnaf Mulugeta, Frank Grosveld

Single-nucleus multiomics of murine gonadal cells reveals transcriptional regulatory network underlying supporting lineage differentiation

Yu-Ying Chen, Karina Rodriguez, Adriana K. Alexander, Xin Xu, Brian Papas, Martin A. Estermann, Humphrey Hung-Chang Yao

From Chen et al. This image is made available for use under a CC0 license.

Lysine-specific demethylase 1a is obligatory for gene regulation during kidney development

Savithri Balasubramanian Kota, Satya K. Kota

| Stem cells, regeneration & disease modelling

Dependence of cell fate potential and cadherin switching on primitive streak coordinate during differentiation of human pluripotent stem cells

Ye Zhu, Aryeh Warmflash

A kinetics-based model of hematopoiesis reveals extrinsic regulation of skewed lineage output from stem cells

Esther Rodríguez-Correa, Florian Grünschläger, Tamar Nizharadze, Natasha Anstee, Jude Al-Sabah, Vojtech Kumpost, Anastasia Sedlmeier, Congxin Li, Melanie Ball, Foteini Fotopoulou, Jeyan Jayarajan, Ian Ghezzi, Julia Knoch, Megan Druce, Theo Aurich, Marleen Büchler-Schäff, Susanne Lux, Pablo Hernández-Malmierca, Julius Gräsel, Dominik Vonficht, Anna Mathioudaki, Judith Zaugg, Ralf Mikut, Andreas Trumpp, Thomas Höfer, Daniel Hübschmann, Simon Haas, Michael D. Milsom

Chronic alcohol consumption enhances the differentiation capacity of hematopoietic stem and progenitor cells into osteoclast precursors

Hami Hemati, Madison B. Blanton, Jude koura, Rupak Khadka, Kathleen A. Grant, Ilhem Messaoud

Dimethyl sulfoxide primes induced pluripotent stem cells for more efficient nephron progenitor and kidney organoid differentiation

Helen Kearney, Aleksandra Rak-Raszewska, Adrián Seijas-Gamardo, Enrique Escarda-Castro, Paul Wieringa, Lorenzo Moroni, Carlos Mota

Quiescence modulates age-related changes in the functional capacity of highly proliferative canine lung mesenchymal stromal cell populations

Nakesha Agyapong, Leslie Dominguez-Ortega, Brian Macdonough, Patrick Mulluso, Sagar Patel, Briti Prajapati, Brian Saville, Andrew Shapiro, Ethan Trim, Kara Battaglia, Jocelyn Herrera, Gianna Garifo-MacPartland, Dianne Newcombe, Latoya Okundaye, Heather Paglia, Julia Paxson

Senolytics restore hematopoietic stem cell function in sickle cell disease

Aditya Barve, Adam Cornwell, Pramika Sriram, Alex Kopyov, Preeti Dabas, Emilia Kooienga, Zakiya Kelley, James Johnson, Jacquelyn A. Myers, Esther A. Obeng, Guolian Kang, Yunus Olufadi, Terri Cain, Lindsay Talbot, David Spence, Mauricio Cortes, Sam Miller, Dirk Loeffler, Akshay Sharma, Shannon McKinney-Freeman

Human pluripotent stem cell-derived intestinal epithelial cells maintain small intestine-specific functions over time, even with repeated cell division

Junlong Chen, So Kuramochi, Shinichiro Horiuchi, Tomoyuki Kawasaki, Hiroto Kakizaki, Lirika Tabata, Tohru Kimura, Kazuaki Nakamura, Hidenori Akutsu, Seiichi Ishida, Akihiro Umezawa

Canonical Hedgehog Signaling Controls Astral Microtubules and Mitotic Spindle Orientation in Neural Progenitors and iPSCs

Fengming Liu, Anna Medyukhina, Kris M Olesen, Abbas Shirinifard, Hongjian Jin, Lei Li, Marina Mapelli, Khaled Khairy, Young-Goo Han

YY1 protein is essential for the promotion of Muller glia reprogramming and retina regeneration

Mansi Chaudhary, Omkar Mahadeo Desai, Poonam Sharma, Sharanya Premraj, Pooja Shukla, Rajesh Ramachandran

Analysis of The Senescence Secretome During Zebrafish Retina Regeneration

Gregory J. Konar, Kyle T. Vallone, Tu D. Nguyen, James G. Patton

Platelet endocytosis and α-granule cargo packaging are essential for normal skin wound healing

Daniëlle M. Coenen, Hammodah R. Alfar, Sidney W. Whiteheart

Cooperation between proximate cell layers drives large-scale wound closure prior to whole-body regeneration

Allison P. Kann, Mansi Srivastava

Ectopic head regeneration after nervous system ablation in a sea anemone

Fatemeh Mazloumi Gavgani, Johanna E.M. Kraus, Joshua November, Layla Al-Shaer, Anna Cosima Seybold, Benjamin Lerstad, Harald Hausen, Michael J. Layden, Fabian Rentzsch

From Gavgani et al. This image is made available under a CC-BY-NC 4.0 International license.

Divergent stem cell mechanisms governing the primary body axis and appendage regeneration in the axolotl

Liqun Wang, Li Song, Chao Yi, Jing Zhou, Zhouying Yong, Yan Hu, Xiangyu Pan, Na Qiao, Hao Cai, Wandong Zhao, Rui Zhang, Lieke Yang, Lei Liu, Guangdun Peng, Elly M Tanaka, Hanbo Li, Yanmei Liu, Ji-Feng Fei

Specific cell states underlie complex tissue regeneration in spiny mice

Emilio Oviedo Rivadeneira, Robyn Allen, Mike Adam, Ashley W. Seifert

A Single Mutation in TRPC6 Protects Mice from Acute Lung Injury by Regenerating Endothelium

Mumtaz Anwar, Vijay Avin Balaji Raghunathrao, Ruhul Amin, Vigneshwaran Vellingiri, Jagdish Chandra Joshi, Md Zahid Akhter, Mohammad Tauseef, Ibrahim Hassan El-Erian, Nazanin Khaki, Ibra S. Fancher, Hazem Abdelkarim, Irena Levitan, Konstantinos Chronis, Vadim Gaponenko, Dolly Mehta

Cloche/Npas4l is a pro-regenerative platelet factor during zebrafish heart regeneration

Junjie Hou, Yabing Song, Chenglu Xiao, Yuanyuan Sun, Jie Shen, Xiaokai Ma, Qinchao Zhou, Shih-Ching Chiu, Yang Xu, Yanyi Huang, Ye-Guang Chen, Xiaojun Zhu, Jianbin Wang, Jing-Wei Xiong

ZEB2 signaling is essential for ureteral smooth muscle cell differentiation and maintenance

Sudhir Kumar, Xueping Fan, Harshita Pattam, Kun Yan, Easton Jinhun Liaw, Jiayi Ji, Emily Zaltz, Paul Song, Yuqiao Jiang, Yuriko Nishizaki, Yujiro Higashi, Chen-Leng Cai, Weining Lu

Intersecting impact of CAG repeat and Huntingtin knockout in stem cell-derived cortical neurons

Jennifer T. Stocksdale, Matthew J. Leventhal, Stephanie Lam, Yu-Xin Xu, Yang Oliver Wang, Keona Q. Wang, Reuben Tomas, Zohreh Faghihmonzavi, Yogi Raghav, Charlene Smith, Jie Wu, Ricardo Miramontes, Kanchan Sarda, Heather Johnson, Min-Gyoung Shin, Terry Huang, Mikelle Foster, Mariya Barch, Naufa Armani, Chris Paiz, Lindsay Easter, Erse Duderstadt, Vineet Vaibhav, Niveda Sundararaman, Dan P. Felsenfeld, Thomas F. Vogt, Jennifer Van Eyk, Steve Finkbeiner, Julia A. Kaye, Ernest Fraenkel, Leslie M. Thompson

A cell-type specific surveillance complex represses cryptic promoters during differentiation in an adult stem cell lineage

Neuza R. Matias, Lorenzo Gallicchio, Dan Lu, Jongmin J. Kim, Julian Perez, Angela M. Detweiler, Chenggang Lu, Benjamin Bolival, Margaret T. Fuller

An increase in reactive oxygen species underlies neonatal cerebellum repair

Anna Pakula, Salsabiel El Nagar, N. Sumru Bayin, Jens Bager Christensen, Daniel N. Stephen, Adam James Reid, Richard Koche, Alexandra L. Joyner

From Pakula et al. This image is made available under a CC-BY-NC 4.0 International license.

Hematopoietic stem cells undergo bidirectional fate transitions in vivo

Tsuyoshi Fukushima, Trine Ahn Kristiansen, Lai Ping Wong, Samuel Keyes, Yosuke Tanaka, Michael Mazzola, Ting Zhao, Lingli He, Masaki Yagi, Konrad Hochedlinger, Satoshi Yamazaki, Ruslan I. Sadreyev, David T Scadden

Muscle stem cell activation in response to acute injury is promoted by transient exposure to neutrophil elastase

Christopher J. Clarke, Amy Stonadge, Ethan Aminov, Addolorata Pisconti

| Plant development

Regulation of early-stage tomato fruit growth by the splicing factor RS2Z36

Stavros Vraggalas, Remus RE Rosenkranz, Mario Keller, Yolanda Pérez-Pérez, Samia Bachiri, Kerstin J Zehl, Jessica Bold, Stefan Simm, Arindam Ghatak, Wolfram Weckwerth, Leila Afjehi-Sadat, Palak Chaturvedi, Pilar S Testillano, Michaela Müller-McNicoll, Kathi Zarnack, Sotirios Fragkostefanakis

Multiple fertility restorer loci for cytoplasmic male sterility caused by orf137 in tomato

Yurie Iki, Issei Harada, Kentaro Ezura, Seira Mashita, Kosuke Kuwabara, Hitomi Takei, Atsushi Toyoda, Kenta Shirasawa, Tohru Ariizumi

Shoot at Site: Advancing in planta transformation, regeneration and gene-editing through a cascade of wounding-mediated developmental regulators

Arjun Ojha Kshetry, Kaushik Ghose, Anshu Alok, Vikas Devkar, Vidhyavathi Raman, Robert M. Stupar, Luis Herrera-Estrella, Feng Zhang, Gunvant B. Patil

Transcriptomic insights into the role of miR394 in the regulation of flowering time in Arabidopsis thaliana

Federico Belen, Yanel Bernardi, Andrea Reutemann, Abelardo Vegetti, Marcela Dotto

Protein and genetic interactions between RACK1A and FSD1 modulate plant development and stress granule-dependent response to salt in Arabidopsis

Pavol Melicher, Petr Dvořák, Maryna Tsinyk, Jan Řehák, Olga Šamajová, Kateřina Hlaváčková, Miroslav Ovečka, Jozef Šamaj, Tomáš Takáč

The ribosomal protein RPS6A modulates auxin signalling and root development in Arabidopsis

Kai Pan, Kai Hou, Mengjuan Kong, Shutang Tan

Spatial and single-cell expression analyses reveal complex expression domains in early wheat spike development

Xiaosa Xu, Huiqiong Lin, Junli Zhang, German Burguener, Francine Paraiso, Connor Tumelty, Chengxia Li, Yuchen Liu, Jorge Dubcovsky

From Xu et al. This image is made available under a CC-BY 4.0 International license.

| Environment, evolution and development

Physical disturbance induces heart stop in mangrove killifish, Kryptolebias marmoratus embryos

Rosalie Herbert, Alexander David Corbett, Tetsuhiro Kudoh

Evolution of developmental bias explains divergent patterns of phenotypic evolution

Joao Picao-Osorio, Charlotte Bouleau, Pablo M. Gonzalez de la Rosa, Lewis Stevens, Nina Fekonja, Mark Blaxter, Christian Braendle, Marie-Anne Félix

Comparative genomics of sex determination related genes reveals shared evolutionary patterns between bivalves and mammals, but not Drosophila

Filippo Nicolini, Sergey Nuzhdin, Fabrizio Ghiselli, Andrea Luchetti, Liliana Milani

Genetic parallels in biomineralization of the calcareous sponge Sycon ciliatum and stony corals

Oliver Voigt, Magdalena V. Wilde, Thomas Fröhlich, Benedetta Fradusco, Sergio Vargas, Gert Wörheide

NSAID-mediated cyclooxygenase inhibition disrupts ectodermal derivative formation in axolotl embryos

Emma J. Marshall, Raneesh Ramarapu, Tess A. Leathers, Nikolas Morrison-Welch, Kathryn Sandberg, Maxim Kawashima, Crystal D. Rogers

Tooth development in frogs: Implications for the re-evolution of lost mandibular teeth and the origin of a morphological innovation

Daniel J Paluh, Madeline Brinkman, Kyliah Gilliam-Beale, Daniela Salcedo-Recio, Jacob Szafranski, James Hanken, Gareth J Fraser

Shaping of developmental gradients through selection on multiple loci in Antirrhinum

Desmond Bradley, Louis Boell, Daniel Richardson, Lucy Copsey, Annabel Whibley, Ting Xu, Yue Zhang, Yongbiao Xue, David Field, Enrico Coen

From Bradley et al. This image is made available under a CC-BY-NC 4.0 International license.

Antero-posterior patterning in the brittle star Amphipholis squamata and the evolution of body plans across echinoderms

L. Formery, P. Peluso, D. R. Rank, D. S. Rokhsar, C. J. Lowe

Parallel adaptation to geothermally-warmed habitats due to common structural variation and functional developmental pathways

Matthew K. Brachmann, Ana P. B. Costa, Shaun Robertson, Kate Donoghue, Natalie Pilakouta, Mark Whitehead, Xuan Liu, Bjarni Kristjansson, Skuli Skulason, Colin Selman, Kevin Parsons

Perinatal Nicotine Exposure Disrupts Hematopoietic Stem Cell Development and Elevates Influenza Susceptibility in Adulthood

T Cool, A Rodriguez y Baena, MGE Rommel, C Mattingly, E Bachinsky, S Saini, S Chattopadhyaya, BA Manso, S Rajendiran, AK Worthington, DM Poscablo, A Deguzman, T Berger-Cahn, DF Boyd, EC Forsberg

Enteric neural crest development in Astyanax mexicanus surface fish and cavefish

Pavani Ponnimbaduge Perera, Kaitlyn Webster, Misty R Riddle

Six million years of vole dental evolution driven by tooth development

Fabien Lafuma, Élodie Renvoisé, Julien Clavel, Ian J. Corfe, Gilles Escarguel

Cell Biology

Dysregulation of cell migration by matrix metalloproteinases in geleophysic dysplasia

Alejo A. Morales, Vladimir Camarena, LéShon Peart, Sarah Smithson, Lindsay Shaw, Lucy Webber, Jose M. Negron, Juan E. Sola, Ann-Christina Brady, Katherina Walz, Gaofeng Wang, Mustafa Tekin

Mitophagy at the oocyte-to-zygote transition promotes species immortality

Siddharthan Balachandar Thendral, Sasha Bacot, Katherine S. Morton, Qiuyi Chi, Isabel W. Kenny-Ganzert, Joel N. Meyer, David R. Sherwood

Treatment of human oocytes with extracellular vesicles from follicular fluid during rescue in vitro maturation enhances maturation rates and modulates oocyte proteome and ultrastructure

Sofia Makieva, Mara D. Saenz-de-Juano, Carmen Almiñana, Stefan Bauersachs, Sandra Bernal-Ulloa, Min Xie, Ana G. Velasco, Natalia Cervantes, Maike Sachs, Susanne E. Ulbrich, Brigitte Leeners

Polarity reversal of stable microtubules during neuronal development

Malina K. Iwanski, Albert K. Serweta, H. Noor Verwei, Bronte C. Donders, Lukas C. Kapitein

Super-resolution compatible DNA labeling technique reveals chromatin mobility and organization changes during differentiation

Maruthi K. Pabba, Miroslav Kuba, Tomáš Kraus, Kerem Celikay, Janis Meyer, Sunik Kumar Pradhan, Andreas Maiser, Hartmann Harz, Heinrich Leonhardt, Karl Rohr, Michal Hocek, M. Cristina Cardoso

Drosophila embryo cellularization is modulated by the viscoelastic dynamics of cortical-membrane interactions

Kyle Stark, Mayte Bonilla Quintana, Anna Marie Sokac, Padmini Rangamani

Drosophila larval gut transcriptome reveals a microbe-mediated intestinal tissue growth via Ecdysone during adaptive growth

Longwei Bai, Stéphanie Bellemin, Coralie Drelon, Pauline Joncour, Elodie Guillemot, Maura Strigini, Benjamin Gillet, François Leulier, Cathy Isaura Ramos

Remodeling of extracellular matrix collagen IV by MIG-6/papilin regulates neuronal architecture

Malika Nadour, Robert I. Valette Reveno Leatis, Marie Biard, Noémie Frébault, Lise Rivollet, Philippe St-Louis, Cassandra R. Blanchette, Andrea Thackeray, Paola Perrat, Carlo Bevilacqua, Robert Prevedel, Laurent Cappadocia, Georgia Rapti, Maria Doitsidou, Claire Y. Bénard

Prolonged metaphase II arrest weakens Aurora B/C- dependent error correction in mouse oocytes

Antoine Langeoire, Alison Kem-Seng, Damien Cladière, Katja Wassmann, Eulalie Buffin

Mammalian oocytes receive maternal-effect RNAs from granulosa cells

Caroline A. Doherty, Abdulfatai Tijjani, Steven C. Munger, Diana J. Laird

Molecular organization of the distal tip of vertebrate motile cilia

Juyeon Hong, Chanjae Lee, Ophelia Papoulas, Jiehong Pan, Maki Takagishi, Nadia Manzi, Daniel Dickinson, Amjad Horani, Steven Brody, Edward Marcotte, Tae Joo Park, John B Wallingford

From Hong et al. This image is made available under a CC-BY 4.0 International license.

Cell-penetrating peptide-mediated mouse oocyte activation

Toru Suzuki

Rapid pronucleus assembly using cytoplasmic RNAs in fertilized eggs of Xenopus laevis

Mizuki Ikeda, Yuto Tanaka, Tatsuya Shohoji, Yuki Hara

A Critical Role for the Fascin Family of Actin Bundling Proteins in Axon Development, Brain Wiring and Function

Katherine R. Hardin, Arjolyn B. Penas, Shuristeen Joubert, Changtian Ye, Kenneth R. Myers, James Q. Zheng

Dysregulation of the actin cytoskeleton and FMRP causes polar body protrusion defects in human fragile X premutation and aged oocytes

Kelly McCarter, Madhura Deshpande, Phillip Romanski, Christina Anna Stratopoulou, Nikica Zaninovic, Momina Tareen, Razan Al-Mousawi, Daylon James, Advaitha Madireddy, Zev Rosenwaks, Jeannine Gerhardt

NOR1 and Mitophagy: An Insight into Sertoli Cell Function Regulating Spermatogenesis

Bhola Shankar Pradhan, Deepyaman Das, Hironmoy Sarkar, Indrashis Bhattacharya, Subeer S Majumdar

In toto imaging of germ plasm dynamics reveals an essential role for early distribution of germ granules in germline development

Andreas Zaucker, Maria Papafoti, David Corcoran, DaeNia La Shawn La Rodé, Rebecca Leech, Pavle Vrliczak, Pooja Kumari, Karuna Sampath

Modelling

Predicting organoid morphology through a phase field model: insights into cell division and lumenal pressure

Sakurako Tanida, Kana Fuji, Linjie Lu, Tristan Guyomar, Byung Ho Lee, Alf Honigmann, Anne Grapin-Botton, Daniel Riveline, Tetsuya Hiraiwa, Makiko Nonomura, Masaki Sano

Modeling Epithelial Morphogenesis and Cell Rearrangement during Zebrafish Epiboly: Tissue Deformation, Cell-Cell Coupling, and the Mechanical Response to Stress

Sharon B. Minsuk, T. J. Sego, David M. Umulis, Mary C. Mullins, James A. Glazier

Generative model for the first cell fate bifurcation in mammalian development

Maria Avdeeva, Madeleine Chalifoux, Bradley Joyce, Stanislav Y. Shvartsman, Eszter Posfai

Mathematical modelling predicts novel mechanisms of stream confinement from Trail/Colec12/Dan in the collective migration of cranial neural crest cells

Samuel W.S. Johnson, Paul M. Kulesa, Ruth E. Baker, Philip K. Maini

Learning a mechanical growth model of flower morphogenesis

Argyris Zardilis, Alexandra Budnikova, Henrik Jönsson

Tools & Resources

CellFateExplorer: An integrated platform for exploring cell fate

Zhaoyang Huang, Haonan Ma, Yuchuan Peng, Chenguang Zhao, Liang Yu

Deep learning predicts tissue outcomes in retinal organoids

Cassian Afting, Norin Bhatti, Christina Schlagheck, Encarnación Sánchez Salvador, Laura Herrera-Astorga, Rashi Agarwal, Risa Suzuki, Nicolaj Hackert, Hanns-Martin Lorenz, Lucie Zilova, Joachim Wittbrodt, Tarik Exner

Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells

Robert N. Rainey, Sam D. Houman, Louise Menendez, Ryan Chang, Litao Tao, Helena Bugacov, Andrew P. McMahon, Radha Kalluri, John S. Oghalai, Andrew K. Groves, Neil Segil

pholidosis: an R package to compare biological surface patterns

Isaac W Krone

Temperature-dependence of Early Development of Zebrafish and the Consequences for Laboratory Use and Animal Welfare

Angelina Miller, Katja Lisa Schröder, Karsten Eike Braun, Caitlin Steindorf, Richard Ottermanns, Martina Roß-Nickoll, Henner Hollert, Thomas Backhaus

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#DanioDigest (November 2024 thru January 2025)

Posted by , on 3 March 2025


An easily-consumable recap of the latest happenings in the #zebrafish community!

Use these links below to get to the section you want:

Community news

Zebrafish careers

Publications

Preprints

Reviews

Protocols and tools

Popular science news

Community News:

Zebrafish Rock! celebrates its 7th anniversary since its relaunch!

Dr. Sonya Neal receives US Presidential Early Career Award for Scientists and Engineers.

Prof. Jochen Guck awarded The Greve Prize from the German National Academy of Sciences Leopoldina.

Prof. Caren Norden awarded Pfizer Premio Award for Basic Research.

Prof. Iain Couzin awarded the 2024 Fyssen International Prize.

Dr. Itamar Harel promoted to Associate Professor at the The Hebrew University of Jerusalem.

Dr. Patrick Murphy to move to the Department of Molecular Biology and Genetics at Cornell University.

Dr. Philip D. Campbell started as an Assistant Professor at University of Pennsylvania.

Dr. Jason (Chang) Marvin awarded the 2024 MGH Center for Faculty Development (CFD) Outstanding Research Fellow Award.

Dr. Vincenzo Torraca receives the King’s College London Innovative Teaching Award.

Phoebe Reynolds wins the British Neuroscience Association (BNA) award for Public Engagement 2024.


PhDs awarded to:
Dr. Caroline Zandecki of Eve Seuntjens Lab KU Leuven.
Dr. Aaron Hickey of Emília Santos Lab University of Cambridge.
Drs. Tuo Shi. & Chun-Che (Ted) Tseng of Gage Crump Lab at University of Southern California.
Drs. Maya Wilde & Leandro Aluisio Scholz of Ethan Scott Lab at University of Melbourne.


#ZebrafishCareers posted by: 

@sdeoliveira.bsky.social‬ USA (Professorship) 

https://www.linkedin.com/jobs/view/4132535919

‬@ehoffmanlab.bsky.social‬ USA (Postdoc)- Contact directly
https://www.hoffmanlab.net/contact

@o-andersson-lab.bsky.social‬ Sweden (Postdoc) – Contact Directly

https://ki.se/en/people/olov-andersson

‪@cao-lab.bsky.social‬ USA (Postdoc)

https://www.caolab.net

@c-henriques-tria.bsky.social UK (Postdoc)

https://www.jobs.ac.uk/job/DLD924/research-associate

@rmarinjuez.bsky.social‬ Canada (Postdoc)

@robparton.bsky.social Australia (PhD)- Submit a brief CV and an outline of research interests to thomas.hall@imb.uq.edu.au

@zebrafish007.bsky.social‬ USA (Lab Manager)

https://careers.criver.com/job/Bethesda-Research-Specialist-IV-Lab-Manager-MD-20892/1232548900

@pdcampbell.bsky.social USA (All levels) 

https://www.pdcampbelllab.com/join-the-labcontact

@aburger2009.bsky.social‬ USA (All levels)

https://medschool.cuanschutz.edu/orthopedics/research/labs/burger-lab/lab-members

Publications:

Developmental Biology & Morphogenesis

‪@yanivelkouby.bsky.social‬ (Oocyte polarity/ Balbiani body/ Bimolecular condensation)

https://www.cell.com/current-biology/fulltext/S0960-9822(24)01623-3

@akankshi.bsky.social (Morphogenesis/ Inner ear semicircular canals/ Versican)

https://journals.biologists.com/dev/article/152/1/dev203003/364931/Versican-controlled-by-Lmx1b-regulates-hyaluronate

‪@chazhong.bsky.social (Acid homeostasis/ Myotome/ T-tubules)

https://anatomypubs.onlinelibrary.wiley.com/doi/epdf/10.1002/dvdy.770

@cristinapujades.bsky.social (Hindbrain boundaries/ Neural progenitors/ Her9)

https://journals.biologists.com/dev/article/152/1/dev203164/364841/Her9-controls-the-stemness-properties-of-hindbrain

@Schierlab.bsky.social (5’ UTR/ Translation initiation control/ Embryogenesis)

https://www.sciencedirect.com/science/article/pii/S1534580724007779

@rentmeisterlab.bsky.social‬ (Development/ mRNA/ FlashCaps)

https://www.nature.com/articles/s42004-025-01411-7?s=09

@nathaliejuya.bsky.social‬ (Motile cilia/ Neuronal activity/ Astroglia) 

https://www.sciencedirect.com/science/article/pii/S2211124724015468?via%3Dihub

#LindseyBarske (Sox10, Bone mineralization, Neural crest) 

https://journals.biologists.com/dev/article/152/2/dev204357/365396/Sox10-is-required-for-systemic-initiation-of-bone

Neuroscience & Behavior

@schoppik.com (Vestibulo-ocular reflex)

https://www.science.org/doi/10.1126/science.adr9982

@gabrielbosse.bsky.social‬ (Sensorimotor behavior/ Stimuli assay) 

https://www.sciencedirect.com/science/article/pii/S0166432824005680?via%3Dihub

#DouglassLab #UniversityofUtah (Oxytocin/ Social behavior/ Danionella cerebrum) 

https://www.cell.com/current-biology/fulltext/S0960-9822(24)01578-1

‪@mydennis.bsky.social‬ (Autism/ Megalencephaly/ YTHDF2)

https://onlinelibrary.wiley.com/doi/10.1002/aur.3314

Stem Cells & Regeneration

@bakkerslab.bsky.social‬ (Cardiomyocytes / Hmga1/ Heart regeneration)

https://www.nature.com/articles/s44161-024-00588-9.epdf?sharing_token=FecKlfbRHf_lEvRZWO9fstRgN0jAjWel9jnR3ZoTv0NiESnQBUOPp1uXhMb9TUBwWdpuezxpoqExC1aanHrWL2hkwTCqFSx21-IDnmzjw-O6HeKsOG_e7uirDOxSXeLtT5XuKsqR0rKdRzx83SdKMS1iHe9Rn3b5nI7BgR-kteo%3D

#LiLiLab #ChineseAcademyofSciences (Tango6/ HSPC proliferation/ Haematopoiesis) 

https://journals.biologists.com/dev/article/152/1/dev202903/364840/Tango6-regulates-HSPC-proliferation-and-definitive

#BushraRajLab #UPenn (Notch signaling/ scRNA-seq/ Neurogenesis)

https://journals.biologists.com/dev/article/151/24/dev203102/364828/Barcoding-Notch-signaling-in-the-developing-brain

Molecular & Cellular Biology

@singhlab.bsky.social (Pancreas/ Beta-cell proliferation/ Cell death) 

https://www.embopress.org/doi/full/10.1038/s44318-024-00332-w

#ChengtianZhaoLab #OceanUniversityofChina (Cilia/ Intraflagellar transport)

https://elifesciences.org/articles/93168?utm_source=bluesky&utm_medium=social&utm_campaign=organic

@mariebreau.bsky.social‬ (ECM/ Basement membrane/ Olfactory system development) 

https://elifesciences.org/articles/92004

@profmariya.bsky.social‬ (Coloboma/ Microphthalmia/ Netrin-1)

https://onlinelibrary.wiley.com/doi/epdf/10.1111/cge.14651

Genetics & Evolution

@migueldvalmeida.bsky.social‬ (Phenotypic diversity/ Transposable elements/ Cichlids)

https://genomebiology.biomedcentral.com/articles/10.1186/s13059-025-03475-z

#ChristophEnglertLab #FritzLipmannInstitute (Sex determination/ TGF-β/ Zebrafish/ Medaka)

https://www.nature.com/articles/s41467-025-55899-7

@yanivelkouby.bsky.social‬ (Germline development/ Asz1/ piRNA)

https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010868&?utm_id=plos111&utm_source=internal&utm_medium=email&utm_campaign=author#ack

Physiology & Environmental Biology

@jaydebon.bsky.social (Climate change/ Thermal tolerance/ Plasticity)

https://www.sciencedirect.com/science/article/pii/S0306456524002420

@cosimaporteus.bsky.social‬ (Hypoxia/ Olfaction/ Sensory physiology) 

https://journals.biologists.com/jeb/article/228/1/jeb249771/364956

@ccioannou.bsky.social‬ (Dynamic color change/ Background matching/ Signalling) 

https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.241073

Microbiology & Host-Pathogen Interactions

‪@sergemostowylab.bsky.social‬ (Bacterial communities/ Microbiota/ Bacterial competition

https://www.sciencedirect.com/science/article/pii/S0966842X24003251#ks0005

@effiebastounis.bsky.social, @sergemostowylab.bsky.social (Cell competition/ ERK activation waves/ Bacterial infection)

https://www.sciencedirect.com/science/article/pii/S2211124724015444?via%3Dihub

Biomechanics & Biophysics

@vermotlab.bsky.social‬ (Mechanical stimulus/ Calcium influx/ Endocardial cells) https://app.jove.com/t/67604/manipulating-mechanical-forces-developing-zebrafish-heart-using 

#Preprints:

Neuroscience & Behavior

@shivangiv10.bsky.social‬ (Synaptic pruning/ Olivocerebellar system)

https://www.biorxiv.org/content/10.1101/2025.01.01.630979v1

@lyons-lab.bsky.social‬ (Myelination/ Schwann cells/ Olig2)

https://www.biorxiv.org/content/10.1101/2025.01.10.632348v1

#WolfgangDrieverLab @uni-freiburg.de (Amygdala/ Behavior/ Tyrosine hydroxylase)

https://www.biorxiv.org/content/10.1101/2025.01.27.635026v1

Developmental Biology & Morphogenesis

#MartikLab #UCBerkeley (Heart regeneration/ Cardiac neural crest/ Transcriptional program) 

https://www.biorxiv.org/content/10.1101/2025.01.16.633462v1

@bryjalab.bsky.social‬ (Wnt/ PCP complex/ Proximity interactomics) 

https://www.biorxiv.org/content/10.1101/2025.01.15.633117v1

@juliaeckert.bsky.social‬ (Tissue morphogenesis/ Image analysis methods/ Nematic order) 

https://www.biorxiv.org/content/10.1101/2025.01.28.635015v1

#JamesJontesLab #OhioStateUniversity (Circuit assembly/  δ-protocadherin/ Optic tectum)

https://www.biorxiv.org/content/10.1101/2025.01.29.635523v1

Stem Cells, Regeneration & Healing

@ditalialab.bsky.social (Regeneration/ Erk signaling/ Osteoblasts)

https://www.biorxiv.org/content/10.1101/2025.01.23.634576v1

#Leach & #Gross Labs (Retinal pigment epithelium/ Photoreceptors/ Regeneration)

https://www.biorxiv.org/content/10.1101/2025.01.10.632236v1

@singhlab.bsky.social‬ (Hepatocyte regeneration/ Cholangiocytes/ Plasticity)

https://www.biorxiv.org/content/10.1101/2025.01.09.629100v1

‪@o-andersson-lab.bsky.social‬ (Hepatic ductal cells/ HER family genes Regeneration) 

https://www.biorxiv.org/content/10.1101/2025.01.09.631719v1

Genetics, Evolution & Molecular Biology

@crumplab.bsky.social‬ (Outer ear evolution/ Single-cell Multiomics) 

https://www.nature.com/articles/s41586-024-08577-5

@varshneylab.social (CRISPR Base editors/ Genome manipulation)

https://www.biorxiv.org/content/10.1101/2025.01.28.635338v1

Metabolism & Disease

@sgraingerphd.bsky.social (Congenital NAD deficiency disorders/ Teratogens) 

https://www.biorxiv.org/content/10.1101/2025.01.10.632366v1

@dagansegal.bsky.social‬ (Cellular plasticity/ Caveolin-1/ Ewing sarcoma)

https://www.biorxiv.org/content/10.1101/2024.09.23.614468v2

Endocrinology & Cellular Signaling

@jfrawls.bsky.social (Enteroendocrine cells/ Peptide hormones/ Neurogenin3)

https://www.biorxiv.org/content/10.1101/2025.01.17.633579v1

#Reviews:

‪@erezraz.bsky.social‬ (Cell migration/ Primordial germ cells) 

https://www.sciencedirect.com/science/article/pii/S0070215325000134?via%3Dihub

@o-andersson-lab.bsky.social‬ (Diabetes/ Beta-cell regeneration) 

https://www.nature.com/articles/s41589-024-01822-y

#Protocols and Tools:

‪@lynneusneddon.bsky.social‬ (Euthanasia/ Electric current/ Animal welfare)

https://www.nature.com/articles/s41598-025-87540-4

@miherbert.bsky.social (Eosinophils/ Immune response)

https://academic.oup.com/jimmunol/article/213/12/1893/7960519?login=true

 ‪@sethblackshaw.bsky.social‬ (MetaLigand database/ Non-peptide ligands interactions) 

https://www.biorxiv.org/content/10.1101/2025.01.14.633094v1

@immler.bsky.social (FishPi/ PiRNA/ Transposons) 

https://link.springer.com/epdf/10.1186/s13100-025-00342-3?sharing_token=OubaNl1l3qdle0gSoTBIAG_BpE1tBhCbnbw3BuzI2RN98Eje-HeUpNfwhGB5Lwy7A5uX4zjeTrz27MmW4lS0cENKo78CSO4ZcQYcYyyKdbLUPHGFz_HqutxeeRk3G01_lOcDoQ12KpqxNzgjfw0qb7mdVXjB32W83RjMXMUHCOM%3D

Link to app: https://github.com/alicegodden/fishpi

@gbdownes.bsky.social‬ (Marigold/ Pose tracking/ Behavior) 

https://bmcbioinformatics.biomedcentral.com/articles/10.1186/s12859-025-06042-2

@noelresearchlab.bsky.social (morphoHeart/ Morphometric analysis) 

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002995

Popular Science News: 

Clinical trial using zebrafish xenografts (Dr. Rita Fior Lab) https://www.science.org/content/article/fish-implanted-tumor-cells-could-help-oncologists-quickly-personalize-cancer-treatments 

Link to LinkedIn post: https://www.linkedin.com/posts/zebrafishrock_daniodigest-zebrafish-phds-activity-7299055638905503744-tuoA?utm_source=share&utm_medium=member_desktop&rcm=ACoAAFBIZScB1XZ47vLDomfVottzYLyczPZx56k
Link to Bluesky post: https://bsky.app/profile/zebrafishrock.bsky.social/post/3liqvlrsdvq25

Special thanks to Maddie Ryan, Charli Corcoran & Michaela Noskova Fairley for putting this digest together! If you would like to thank the Zebrafish Rock! team for their time & effort, you can buy us a strong cuppa at the link below. Every little bit keeps us caffeinated and motivated! We appreciate your support 🙂
🙏 https://buymeacoffee.com/zebrafishrock 
Fin!

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ISSCR 2025 Annual Meeting: Where Scientific Discoveries, Biotech Innovations, and Clinical Breakthroughs Converge

Posted by , on 2 March 2025

The ISSCR Annual Meeting, taking place in Hong Kong on 11-14 June, is a gathering of the brightest minds in stem cell research and regenerative medicine across geographies and disciplines. Nearly 4,000 scientists from around the globe will convene at ISSCR 2025 to take part in a 4-day program comprising the year’s most significant new advances in the fields of stem cell research and regenerative medicine. 

Visit https://www.isscr2025.org/ to learn more about registration, abstract submission, and to view the full scientific program.  Do not miss the final opportunity to present your work at ISSCR 2025 – late-breaking abstracts are due 19 March, and there will be no deadline extensions.

The scientific program is organized around 6 tracks:  

  • Clinical Applications 
  • Disease Modeling and Drug Discovery 
  • Global Stakeholder Initiatives 
  • Organ Generation and Regeneration 
  • Pluripotency and Development 
  • Somatic Stem Cells and Cancer 

The ISSCR 2025 Annual Meeting is the place to meet potential collaborators and network with stem cell and regenerative medicine researchers from around the world. One-on-One Partnering and ample networking opportunities help attendees make vital connections that drive new discoveries and accelerate progress. More than 250 scientific talks will be presented across the 4-day program, as well as 1,400+ scientific poster presentations.  

Meeting Co-Chairs:  

  • Kathryn Cheah, PhD, The University of Hong Kong, Hong Kong 
  • Eugenia Piddini, PhD, University of Bristol, UK 

Meeting Organizing Committee: 

  • Alessandro Aiuti, MD, PhD, San Raffaele Telethon Institute for Gene Therapy, Italy 
  • Vivian Gama, PhD, Vanderbilt University, USA 
  • Richard J. Gilbertson, MD PhD, CRUK Cambridge Institute, UK 
  • Valentina Greco, PhD, Yale School of Medicine, Genetics Department & Yale Stem Cell Center, USA 
  • Lijian Hui, PhD, Shanghai Institute of Biochemistry and Cell Biology (SIBCB), China 
  • Tina Mukherjee, PhD, Institute for Stem Cell Science and Regenerative Medicine (inStem), India 
  • Lygia da Veiga Pereira, PhD, Universidade de São Paulo, Brazil 
  • Kirstin Sadler Edepli, PhD, NYU Abu Dhabi, United Arab Emirates 
  • Takanori Takebe, MD, PhD, Cincinnati Children’s Hospital Medical Center, USA and Osaka University and Tokyo Medical and Dental University, Japan  
  • Angela R. Wu, PhD, Hong Kong University of Science and Technology, Hong Kong 
  • Joseph C. Wu, MD PhD, Stanford University, USA 
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Categories: Events, Societies, Uncategorized

The Node Time Machine – February 2011

Posted by , on 27 February 2025

At the end of each month, I pick a random year from the past 15 years of the Node, and take a look at what people were talking about back then.

Since this is the first time I’m travelling via the Time Machine, I’ve picked the first ever February that the Node experienced, back in 2011. Let’s step into the machine, and turn the dial to February 2011…

Definitions

If you scroll down to the comments section, you might find a few familiar names discussing the definitions of stem cells vs progenitors. 14 years on, what are people’s views on this?

Careers

Here, Sarah Gibb told the story of how she took the leap and applied for a job at the Glasgow Science Centre after her PhD. Since that blog post, we have featured many interesting career stories on the Node. Browse through the collection.

Science and fashion

How amazing is this? Dresses that represent different human embryonic developmental stages. Head over to the website about the exhibit to find out more!

Featured resource

Emma Kemp from EuroStemCell was very active on the Node from 2011-2012. In 2020, EuroStemCell was superseded by EuroGCT, but people can still find useful resources around stem cell research on their website.
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Categories: Highlights

Are you the recipient of a Travelling Fellowship? Tell us your story

Posted by , on 27 February 2025

Did you know that The Company of Biologists’ journals –  DevelopmentJournal of Cell ScienceJournal of Experimental Biology and Disease Models & Mechanisms – offer Travelling Fellowships to early-career researchers (graduate students and postdocs) so that they can make collaborative visits to other research laboratories across the world? The first cohort of Travelling Fellowships was launched for Development in 1990, which was later extended to Journal of Cell Science (JCS) in 1992 and Journal of Experimental Biology (JEB) in 1996. Disease Models & Mechanisms (DMM), being a relatively younger journal (you can read about DMM’s origin in this Editorial), offered Travelling Fellowships to ECRs since it was launched in 2008.

As we celebrate the Company’s 100th birthday in 2025 (you can find out more about us in this recent Editorial), we would love to hear stories from you – our community – about how the Company has helped you in your scientific journey. If you ever received a Travelling Fellowship that enabled you to travel to other research labs, particularly in the period from 1990 to early 2000s, do get in touch and let us know about your experience and how this has impacted your career.

You can tell us your story by sending your own digital ‘message in a bottle’ in honour of the founder of the Company, George Parker Bidder III.

You can also share your story by replying to this post or to any of our social media posts with #biologists100 hashtag on Bluesky and X.

I am a Cross-title Features Editor at The Company of Biologists. So, you can also directly send your stories to me at saanjbati.adhikari@biologists.com or to our Science Communications Officer at scicomms@biologists.com.

Following your response, I might contact you to learn a bit more about your experience and career trajectory.

We look forward to hearing back from you.

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Categories: News, Outreach

Join us as an intern working across the Node, preLights & FocalPlane

Posted by , on 26 February 2025

The Company of Biologists is looking for one or more interns, through the BBSRC DTP/PIPS or equivalent schemes, to work on our community sites – the Node, preLights and FocalPlane. This is a great opportunity to gain experience in the rapidly growing online science communication environment, to develop writing skills, and to learn about academic publishing.

Together, the Company’s three community sites provide platforms for the research community to share news, discuss issues relevant to the field, and read about the latest research and events.

The Node is a field-specific site for developmental biologists, FocalPlane aims to bring together the microscopy and biology communities, and preLights is focussed on highlighting the preprint literature and exploring the journey from preprint to publication. The intern will be involved in the day-to-day running of one or more of the sites and will be mentored by the relevant Community Manager(s). The internship will be based in our office in Cambridge, though hybrid working opportunities may be available.

Core responsibilities of the position include:

  • Creating and commissioning content, including writing posts and soliciting content from the academic community, societies and other organisations
  • Providing user support
  • Helping to run the community site social media accounts.

The successful intern will have:

  • Relevant scientific expertise (ideally in the developmental or cell biology field, though we are open to applications from individuals working in other areas of biology)
  • Strong writing and communication skills
  • Keen interest in science communication, ideally including experience in blogging and/or social media. Familiarity with WordPress would be a bonus.

We are looking for an intern to start in early summer 2025 and encourage interested candidates to submit their application as soon as possible.

To apply, please send a CV and cover letter, stating why you are interested in this opportunity, to recruitment@biologists.com and Katherine Brown (Development’s Executive Editor) at katherine.brown@biologists.com. Please also direct informal enquiries to the same addresses.

We also offer internship opportunities for students more interested in data-type projects. Details of these can be found at https://www.biologists.com/wp-content/uploads/DataInt.pdf

More information: https://www.biologists.com/about-us/work-for-us/

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Developmental timing across species | EMBO Workshop | 6-9 May

Posted by , on 25 February 2025

Join us at the EMBO Workshop “EvoDevoTempo – Developmental Timing Across Species: From Mechanisms to Evolutionary Insights”.

Topics will include theoretical modelling, metabolism, and evolutionary biology, thus bringing a uniquely interdisciplinary perspective to the meeting.

Sessions:

  • Developmental timing in vivo
  • in vivo & in vitro models for timing
  • Metabolic rates and timing
  • in vitro & in silico models for timing
  • Cell dynamics and timing
  • Timing in homeostasis
  • New molecular mechanisms of timing

Where: Paris Brain Institute, France

When: May 6-9 2025

Abstract submission and registration deadline: 1 April 2025

Register: https://meetings.embo.org/event/25-dev-timing

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Categories: Events

3-year PhD position on environmental impact on animal development

Posted by , on 25 February 2025

Closing Date: 20 June 2025

Brief description of the project: The marine environment is under increasing thermal stress due to climate change. This is a major issue for development in poikilothermic animals that have thermal limits for correct development at the egg stage. Degradation in eggs quality has been a recent major issue in additionally for agriculture and human health. Prof Sato’s research group has been investigating the molecular basis of developmental robustness under thermal stress (https://www-p.sci.ocha.ac.jp/bio-atsuko-en/) and how environmental stress could have altered developmental pathways in the evolutionary process with a special focus on maternal factors. The goal of this project is to predict development and body patterning from initial maternal input by mathematical modelling. We also aim to identify heritable phenotypes by maternal environment, but not by the genome, using surrogate fish technology.

The student will be engaged in computer programing to create a mathematical model and molecular work involving collecting tissue and RNA samples from fish and/or tunicates. Molecular work will involve collecting tissue and RNA samples and the student will have opportunity to learn RNA extraction, PCR, immunohistochemistry, HR and imaging analysis, under the guidance of Dr. Sato. In the computational work, the student will learn programming and simulation, but this requires experience and basic skills in programming using python and R.

Applicant eligibility: A female student who has Master’s degree or going to obtain Master’s degree in a relevant field of study, either in mathematical or computer science or biological sciences with a strong computational or bioinformatics component by the starting date of PhD. We are looking for motivated student interested in animal biology, developmental biology, programming with problem solving abilities as well as resilience to solve daily problems. Research experience in molecular biology and basic programming would be advantageous. This position is open to applications from all nationalities.

Application deadline: 1 June 2025 midnight JST, open until filled.

The studentship will start 01 October 2025 the earliest. Full time only.

For more details, please visit:

https://www-p.sci.ocha.ac.jp/bio-atsuko-en/Joiningus.html
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Categories: Jobs

New correspondents for the Node – welcome!

Posted by , on 24 February 2025

Let’s welcome the three new Node correspondents – Dosh Whye, Mariia Golden and Shefali! We look forward to working with them to bring you a wide range of content and perspectives for the Node. Stay tuned for their posts over the coming year.

Image credit: Fritz et al. 2013

Dosh Whye serves as the assistant director of the Human Neuron Core, where he leads the cell development and differentiation efforts to build complex 3D neural organoid models using induced pluripotent stem cells (iPSCs) from pediatric patients with rare genetic neurodevelopmental disorders. Dosh has close to 20 years in the stem cell field, and he continues to be fascinated by the power of pluripotent cells and the technological advancements of stem cell applications in the fields of science & medicine. He plans to serve as a correspondent for several international stem cell research conferences, and he’s also inspired to write a Q&A blog series profiling many brilliant scientists in the stem cell field.

Mariia Golden is a third-year PhD student moving from Goethe University Frankfurt to Marburg University, Germany. She investigates dynamical morphogenetic events in insect development. She is passionate about live imaging and working with non-model organisms. As a Node correspondent, Mariia wants to promote diversity among the organisms we choose for our research questions through a series of interviews with established scientists who are enthusiastic about the topic. She also would like to highlight the topic of motherhood and scientific career, because she truly believes that the status quo should change in order to put a stop to the “brain drain” through female scientists. 

Shefali is a fifth-year PhD student in the Tennessen Lab at Indiana University, Bloomington. She is broadly interested in inter-organ metabolic signaling, and her current research focuses on how glucose metabolism coordinates the brain-body growth signaling axis during Drosophila melanogaster brain development. Shefali also serves as the elected graduate student representative on the FlyBoard, where she has been working towards creating more mentoring opportunities for early career scientists. Beyond work, she enjoys learning various Latin-style dances and singing classic Hindi songs (which is her mother tongue). As a Node correspondent, she is eager to combine her scientific interests with her commitment towards building a strong and empowered scientific community. She looks forward to writing not only about the emerging field of inter-organ metabolic signaling, but also about unconventional scientific journeys, community resources, importance of mentoring, and bring in her perspective as a trainee to support incoming graduate students.

Our sister community site FocalPlane also announced their three new correspondents. Meet the new FocalPlane correspondents.

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